Social Reasoning in Psychopathy

精神病态的社会推理

• 批准号: 8059684
• 负责人: Elsa Ruth Ermer
• 金额: $ 5.44万
• 依托单位: UNIVERSITY OF NEW MEXICO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8059684
• 关键词: Address; Affect; Affective; Amygdaloid structure; Animals; Anterior; Area; Base of the Brain; Behavior; Behavioral; Bilateral; Brain; Brain imaging; Brain region; Chronic; Cognitive; Communities; Contracts; Data; Decision Making; Detection; Emotional; Event; Evolution; Female; Frequencies; Functional Magnetic Resonance Imaging; Functional disorder; General Population; Goals; Human; Image; Image Analysis; Impairment; Imprisonment; Incidence; Individual; Intelligence; Lead; Limbic System; Magnetic Resonance Imaging; Mental disorders; Mind; Nature; Neurocognitive; New Mexico; Output; Participant; Patients; Pattern; Performance; Personality Disorders; Population; Prisoner; Prisons; Process; Psychopath; Reaction Time; Recruitment Activity; Relative (related person); Research; Rest; Sampling; Social Conditions; Specificity; Substance abuse problem; System; Temporal Lobe; Woman; Work; base; cingulate cortex; cost; effective therapy; expectation; high risk; independent component analysis; male; men; psychopathic personality; relating to nervous system; social; theories; treatment strategy

DESCRIPTION (provided by candidate): Psychopathy is a serious personality disorder with interpersonal, affective, and behavioral components. One hallmark of psychopathy is the persistent violation of social contracts, i.e., cheating. In a cooperative species such as humans, the societal costs of this behavior are tremendous. Indeed, the frequency and extent of (normal) humans' cooperation is astounding compared to the rest of the animal kingdom. Evolutionary analyses have identified several cognitive abilities necessary for cooperation to evolve, including the ability to detect cheaters. A large body of data has demonstrated that normal individuals are adept at detecting cheaters when reasoning about social exchange, and evidence about which brain regions underlie this ability has begun to accrue. Both the behavioral and neural data indicate that social exchange reasoning is functionally distinct from other types of reasoning (e.g., precautionary reasoning). The goal of the proposed research is to investigate social exchange reasoning in psychopathy. Specifically, the aim is to address the following questions: Is reasoning about social exchange (i.e., cheater detection) impaired in psychopathy? Do psychopaths recruit the same brain regions to reason about social exchange that normal, healthy individuals do? Does social exchange reasoning show the same relationship with emotional intelligence in psychopaths as it does in normal individuals? The proposed studies employ event-related functional magnetic resonance imaging to investigate the behavioral performance and brain basis of incarcerated psychopaths' and control participants' reasoning about social exchange, precautionary, and social descriptive rules, using the Wason selection task. Including these two types of rules will allow us to investigate the specificity of the results to social exchange. Normal individuals perform equally well on social exchange and precautionary rules; psychopaths are high risk-takers,suggesting precautionary reasoning will be informative. Social descriptive rules are also social in nature, but fail to fit the input conditions for social exchange rules; normal individuals are very sensitive to this distinction. The Wason selections task is ideal for imaging studies in that the three types of reasoning problems differ only in their content-the task demands are identical across problem type.

描述（由考生提供）：精神病是一种严重的人格障碍与人际关系，情感和行为的组成部分。精神变态的一个标志是持续违反社会契约，即，作弊在人类这样的合作物种中，这种行为的社会成本是巨大的。事实上，与动物王国的其他部分相比，（正常）人类合作的频率和程度令人震惊。进化分析已经确定了合作进化所必需的几种认知能力，包括检测作弊者的能力。大量的数据表明，正常人在推理社会交换时擅长发现作弊者，关于这种能力的大脑区域的证据已经开始积累。行为和神经数据都表明，社会交换推理在功能上不同于其他类型的推理（例如，预防推理）。 本研究的目的是探讨精神病患者的社会交换推理。具体来说，目的是解决以下问题：推理是关于社会交换的（即，作弊者检测）在精神病中受损？精神病患者是否会像正常健康的人一样，使用相同的大脑区域来推理社会交换？在精神病患者中，社会交换推理与情绪智力的关系是否与正常人相同？ 拟议的研究采用事件相关功能磁共振成像调查的行为表现和大脑基础的监禁精神病患者和控制参与者的推理社会交换，预防和社会描述规则，使用Wason选择任务。包括这两种类型的规则将使我们能够研究结果的特殊性，以社会交换。正常人在社会交换和预防规则方面表现同样出色;精神病患者是高风险承担者，这表明预防推理将提供信息。社会描述性规则在本质上也是社会性的，但不符合社会交换规则的输入条件;正常的个体对这种区分非常敏感。Wason选择任务是理想的成像研究中，三种类型的推理问题的不同之处仅在于其内容的任务要求是相同的跨问题类型。

项目成果

Aberrant paralimbic gray matter in incarcerated male adolescents with psychopathic traits.

• DOI: 10.1016/j.jaac.2012.10.013
• 发表时间: 2013-01
• 期刊: Journal of the American Academy of Child and Adolescent Psychiatry
• 影响因子: 13.3
• 作者: Ermer E;Cope LM;Nyalakanti PK;Calhoun VD;Kiehl KA
• 通讯作者: Kiehl KA

Paralimbic gray matter reductions in incarcerated adolescent females with psychopathic traits.

• DOI: 10.1007/s10802-013-9810-4
• 发表时间: 2014-05
• 期刊: Journal of abnormal child psychology
• 影响因子: 3.6
• 作者: Cope LM;Ermer E;Nyalakanti PK;Calhoun VD;Kiehl KA
• 通讯作者: Kiehl KA

Impaired conditional reasoning in alcoholics: a negative impact on social interactions and risky behaviors?

酗酒者的条件推理受损：对社交互动和危险行为的负面影响？

• DOI: 10.1111/j.1360-0443.2010.03346.x
• 发表时间: 2011
• 期刊: Addiction (Abingdon, England)
• 作者: Kornreich,Charles;Delle-Vigne,Dyna;Knittel,Julian;Nerincx,Aurore;Campanella,Salvatore;Noel,Xavier;Hanak,Catherine;Verbanck,Paul;Ermer,Elsa
• 通讯作者: Ermer,Elsa