Comparison of kidney function measurement methods in the community

社区肾功能测量方法比较

基本信息

  • 批准号:
    8139916
  • 负责人:
  • 金额:
    $ 13.77万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2007
  • 资助国家:
    美国
  • 起止时间:
    2007-09-01 至 2012-12-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): Project Summary: The candidate is a nephrologist starting a staff position at the Mayo Clinic on July 1st, 2006. During the past 4 years as a nephrology trainee, the candidate obtained a Master's degree in Clinical Research, first-authored 10 peer-reviewed articles, and received institutional (T32) and individual (F32) National Research Awards. His expertise in the epidemiology of chronic kidney disease and in kidney function methods has gained national attention. He was a grant reviewer for the Centers for Disease Control and Prevention and will moderate a symposium at the American Society of Nephrology Renal Week (2006). The environment will consist of Mayo Clinic - Rochester, where he will have a joint appointment in Nephrology and Epidemiology. His sponsor, Stephen Turner, M.D., Professor of Medicine, will provide him with access to data and train him to be an independent investigator. His mentorship team will also include two Professors of Epidemiology, an Associate Professor of Biostatistics, and the Co-director of the Renal Function Laboratory where 5500 'gold-standard' kidney function measurements are performed annually. The project will compare kidney function measurements between a gold standard method (iothalamate clearance) and more convenient, but potentially less accurate methods, used in clinical practice and in most studies (serum creatinine, cystatin C, estimating equations, and creatinine clearance). The unique feature of this project will be to compare these kidney function methods in community-based samples (mentor's cohort and candidate's cohort). The effect of the kidney function measurement method on coronary artery calcification and risk factor associations with chronic kidney disease will be determined. Relevence: In the United States, 8 million adults have moderate-to-severe reductions in kidney function and are at risk for costly morbid interventions (dialysis or transplantation) and cardiovascular disease. Validation of kidney function methods is needed to identify chronic kidney disease at an earlier stage, characterize its risk factors, and develop new treatment strategies.
描述(由申请人提供):

项目成果

期刊论文数量(12)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
The association between age and nephrosclerosis on renal biopsy among healthy adults.
  • DOI:
    10.7326/0003-4819-152-9-201005040-00006
  • 发表时间:
    2010-05-04
  • 期刊:
  • 影响因子:
    39.2
  • 作者:
    Rule AD;Amer H;Cornell LD;Taler SJ;Cosio FG;Kremers WK;Textor SC;Stegall MD
  • 通讯作者:
    Stegall MD
Can we do better than a single estimated GFR threshold when screening for chronic kidney disease?
在筛查慢性肾脏病时,我们能否比单一估计的 GFR 阈值做得更好?
  • DOI:
    10.1038/sj.ki.5002452
  • 发表时间:
    2007
  • 期刊:
  • 影响因子:
    19.6
  • 作者:
    Poggio,ED;Rule,AD
  • 通讯作者:
    Rule,AD
Eprodisate slows the progression of renal disease in patients with AA amyloidosis.
依普罗地酯可减缓 AA 淀粉样变性患者肾脏疾病的进展。
Prevalence of CKD in the United States: GFR-estimating equations matter.
美国 CKD 的患病率:GFR 估计方程很重要。
The estimated glomerular filtration rate as a test for chronic kidney disease: problems and solutions.
估计肾小球滤过率作为慢性肾脏疾病的测试:问题和解决方案。
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ANDREW David RULE其他文献

ANDREW David RULE的其他文献

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{{ truncateString('ANDREW David RULE', 18)}}的其他基金

A population-based study of deep learning derived organ and tissue measures for accelerated aging using repurposed abdominal CT images
使用重新调整用途的腹部 CT 图像对深度学习衍生的器官和组织加速衰老措施进行基于人群的研究
  • 批准号:
    10795414
  • 财政年份:
    2023
  • 资助金额:
    $ 13.77万
  • 项目类别:
The Aging Kidney Anatomy Study
衰老肾脏解剖学研究
  • 批准号:
    9243240
  • 财政年份:
    2011
  • 资助金额:
    $ 13.77万
  • 项目类别:
Automated detection of microstructural features that have unique protein markers and are prognostic for chronic kidney disease
自动检测具有独特蛋白质标记且可预测慢性肾脏病的微观结构特征
  • 批准号:
    10444797
  • 财政年份:
    2011
  • 资助金额:
    $ 13.77万
  • 项目类别:
The macro- and micro- anatomy and pathology of the aging kidney
衰老肾脏的宏观和微观解剖学及病理学
  • 批准号:
    8022523
  • 财政年份:
    2011
  • 资助金额:
    $ 13.77万
  • 项目类别:
The macro- and micro- anatomy and pathology of the aging kidney
衰老肾脏的宏观和微观解剖学及病理学
  • 批准号:
    8425058
  • 财政年份:
    2011
  • 资助金额:
    $ 13.77万
  • 项目类别:
The macro- and micro- anatomy and pathology of the aging kidney
衰老肾脏的宏观和微观解剖学及病理学
  • 批准号:
    8602520
  • 财政年份:
    2011
  • 资助金额:
    $ 13.77万
  • 项目类别:
The macro- and micro- anatomy and pathology of the aging kidney
衰老肾脏的宏观和微观解剖学及病理学
  • 批准号:
    8223232
  • 财政年份:
    2011
  • 资助金额:
    $ 13.77万
  • 项目类别:
Automated detection of microstructural features that have unique protein markers and are prognostic for chronic kidney disease
自动检测具有独特蛋白质标记且可预测慢性肾脏病的微观结构特征
  • 批准号:
    10600074
  • 财政年份:
    2011
  • 资助金额:
    $ 13.77万
  • 项目类别:
Comparison of kidney function measurement methods in the community
社区肾功能测量方法比较
  • 批准号:
    7928404
  • 财政年份:
    2009
  • 资助金额:
    $ 13.77万
  • 项目类别:
Comparison of kidney function measurement methods in the community
社区肾功能测量方法比较
  • 批准号:
    7484970
  • 财政年份:
    2007
  • 资助金额:
    $ 13.77万
  • 项目类别:

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