COMMUNITY BASED RESEARCH AND EDUCATION (COBRE) CORE FACILITY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 CTN将在翻译神经科学方面实施一个新的核心设施。转化型研究的一个定义是将基础科学成果应用到床边。然而，在这种情况下，我们将翻译神经科学定义为使用生物医学知识和研究来解决社区中的实际问题。在这个测试案例中，我们将解决儿童健康问题，以便核心设施将总部设在阿肯色州儿童医院(ACH)。 低出生体重(LBW)出生是导致婴儿死亡和残疾的主要原因，是父母压力的主要来源，也是私人和公共医疗保险计划的经济负担。在提供专门产前和围产期护理的医院分娩被认为在改善分娩结局方面有效，可能还会降低医疗成本。然而，居住在农村和服务不足地区的妇女通常无法进入这些中心，也找不到可以协助社区医生诊断和管理高危疾病的孕产妇和胎儿医学专家。 CTN将开始对核心设施进行为期一年的支持试验，该设施将在全州范围内使用由15个互动压缩视频网站组成的网络、一个集中的24小时呼叫中心，以及全州范围内的医生教育和指南制定倡议，以使妇女及其社区医生能够咨询学术专家，并促进基于证据的转介高危妇女到区域围产期中心分娩。除了这些教育活动外，科布雷核心设施还将开始收集关于出生结果的研究数据。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The CTN will implement a new Core Facility in translational neuroscience. One definition of translational research is the application of basic science findings to the bedside. However, in this context, we define translational neuroscience as using biomedical knowledge and research to solve real problems in the community. In this test case, we will address children's health issues so that the Core Facility will be based at Arkansas Children's Hospital (ACH). Low birth weight (LBW) births are a leading cause of death and disability in infants, major sources of stress for parents, and an economic burden for private and public health insurance programs. Delivery at hospitals offering specialized pre- and perinatal care is thought to be effective in improving birth outcomes and perhaps reducing medical costs. However, women residing in rural and underserved areas typically lack access to these centers and to maternal and fetal medicine subspecialists who can assist community physicians with diagnosis and management of high-risk conditions. The CTN will begin a one-year trial of support for a Core Facility that will employ a statewide network of 15 interactive compressed video sites, a centralized 24-hour call center, and a statewide physician education and guideline development initiative to enable women and their community physicians to consult with academic subspecialists and facilitate the evidence-based referral of high-risk women to regional perinatal centers for delivery. In addition to these educational activities, the COBRE Core Facility will begin to gather research data on birth outcomes.