AR CAREER DEVELOPMENT COBRE: PAIN: EARLY EXPERIENCE AND PRE-ATTENTION MECHANISMS

AR 职业发展 COBRE：痛苦：早期经验和预先注意机制

• 批准号: 7171352
• 负责人: WHIT HALL
• 金额: $ 26.56万
• 依托单位: UNIV OF ARKANSAS FOR MED SCIS
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7171352
• 关键词: career; central nervous system; clinical research; educational resource design /development; health science profession; neuropathology

DESCRIPTION (provided by applicant): We will implement a Career Development Program for five Project Principal Investigators (PIs) who are close to nationally competitive levels using grant support and mentoring activities undertaken by established investigators. Each Project involves unique, innovative state-of-the-art research. The goal is to help these PIs secure mentored grants or R01 funding within 1-3 years, replacing them with other investigators close to nationally competitive levels, and helping those investigators secure extramural support. By the end of the award period, our goals are 1) to generate mentored grants and R01 funding for at least seven new investigators, and 2) to secure two additional multi-investigator awards. The Projects chosen have significant synergy, which will facilitate the third goal, 3) the submission of a Program Project application (P01) linking at least three of the new R01 awardees with other established investigators. We will also establish a multi-disciplinary Center for Translational Neuroscience (CTN) that will take advantage of the existing faculty strengths and expand the neuroscience research infrastructure, becoming a hub for campuswide collaborations. The CTN will also benefit from the recruitment of two tenure-track, mid- to senior-level, funded investigators who will also become mentors to Project PIs. In addition, three other faculty of junior rank will be recruited during the life of the award, adding to the critical mass of investigators. Additional potential future PIs will be recruited through a Pilot Study award program. The significant institutional commitment for this effort, will be parlayed into independent extramural support for the Center (P50 award) by the end of the award period. The Director of the CTN has experience with large-scale development programs, Program Project grants and has been Federally funded for over 20 years. We will establish a Core Facility and an Experimental Core, to provide an efficient means of ensuring that sophisticated and expensive instrumentation is fully utilized, maintained and operated by trained professionals. We will ensure that Project PIs have access to state-of-the-art services and facilities (through yearly purchases of new equipment), providing the basic underpinnings of the translational neuroscience research efforts at UAMS.

描述（由申请人提供）： 我们将为五名项目首席研究人员（PI）实施职业发展计划，他们使用批准调查人员开展的赠款支持和指导活动接近国家竞争水平。每个项目都涉及独特，创新的最先进的研究。目的是在1 - 3年内帮助这些PIS安全的指导赠款或R01资金，以接近全国竞争水平的其他调查员取代他们，并帮助这些调查人员获得壁外支持。到奖励期结束时，我们的目标是1）为至少七名新调查人员创造有指导的赠款和R01资金，以及2）获得另外两个多投资奖奖。所选项目具有重要的协同作用，这将促进第三个目标，3）提交计划项目申请（P01），将新的R01获奖者中的至少三个与其他既定调查人员联系起来。我们还将建立一个多学科的转化神经科学中心（CTN），该中心将利用现有的教师优势并扩大神经科学研究基础设施，成为校园范围内合作的枢纽。 CTN还将受益于招募两名终身制轨道，中高级资助的调查人员，他们也将成为PIS项目的导师。此外，该奖项一生中还将招募其他三个初级职级教职员工，从而增加了大量的调查人员。将通过一项试点研究奖计划招募其他潜在的未来PI。在奖励期结束之前，对这项工作的重要机构承诺将成为对该中心的独立壁外支持（P50奖）。 CTN主任拥有大规模开发计划的经验，计划项目赠款，并获得了20多年的联邦资助。我们将建立一个核心设施和一个实验核心，以提供有效的手段，以确保由训练有素的专业人员充分利用，维护和运营精致且昂贵的仪器。我们将确保PIS项目可以访问最先进的服务和设施（通过每年购买新设备），从而为UAMS的转化神经科学研究工作提供了基本的基础。