ADMINISTRATIVE CORE AND ENRICHMENT PROGRAM

行政核心和强化计划

• 批准号: 7767531
• 负责人: Nicholas O. Davidson
• 金额: $ 35.57万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2014-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7767531
• 关键词: Center for Translational Science Activities; Clinical; Clinical and Translational Science Awards; Collection; Core Facility; Data; Databases; Digestive System Disorders; Discipline; Disease; Extramural Activities; Faculty; Functional disorder; Funding; Gastrointestinal Diseases; Gastrointestinal tract structure; Individual; Inflammatory Bowel Diseases; Inflammatory disease of the intestine; Institutes; Institution; Intestines; Investigation; Link; Liver; Maintenance; Medical; Mission; Output; Patients; Phenotype; Physicians; Postdoctoral Fellow; Process; Proteomics; Research; Research Personnel; Research Support; Resources; Sampling; Science; Services; System; Tissue Procurements; Tissues; Training; Translational Research; Universities; Washington; biomedical informatics; cost; functional genomics; graduate student; innovation; interest; member; profession allied to medicine; programs; success

The Washington University DDRCC is integrated with the NIH's Clinical Translational Science Award (CTSA) sponsored Washington University Institute of Clinical Translational Sciences (ICTS), primarily through the Clinical Component ofthe DDRCC and the ICTS Centerfor Biomedical Informatics. The DDRCC Clinical Component is primarily focused on providing investigators with access to clinical samples for digestive diseases related research. The collection and maintenance of clinical samples linked to longitudinal clinical information in a manner that is responsive to our DDRCC investigators, requires a high level of clinical expertise in accurately phenotyping the patient subjects and a high level of stringent oversight in collecting clinical samples. For this reason, organization of tissue procurement at this institution has moved away from a single monolithic institutional unit attempting to collect a broad array of clinical samples from patients with many different diseases. Instead, tissue procurement is being conducted by smaller disease focused units, such as the DDRCC sponsored facility, that are linked to each other by a common biomedical informatics platforms (Tissue Suite and ClinPortal) developed and maintained by the CTSA-sponsored Center for Biomedical Informatics. Furthermore, the data output from two of the Research Core Facilities, the Functional Genomics Core and the Proteomics Core are in the process of being uploaded to databases (Profile DB) maintained by the ICTS Center for Biomedical Informatics.

华盛顿大学DDRCC与美国国立卫生研究院的临床转化科学奖相结合