METAPHASE SPINDLE PROTEOME

中期纺锤体蛋白质组

• 批准号: 8171229
• 负责人: Ahna Renee Skop
• 金额: $ 0.24万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8171229
• 关键词: Cell Cycle Stage; Cell division; Cells; Computer Retrieval of Information on Scientific Projects Database; Cytokinesis; Funding; Goals; Grant; Institution; Lead; Metaphase; Proteins; Proteome; Proteomics; Research; Research Personnel; Resources; Source; Staging; Techniques; United States National Institutes of Health; comparative genomics

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Our goal is to understand the mechanisms of cytokinesis. We are using proteomic and comparative genomic techniques to identify proteins that are required during specific cell cycle stages. Analyzing protein composition of different cell stages may lead to better understanding of the mechanism of cell division by pinpointing proteins specific to particular cell cycle stage.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 我们的目标是了解细胞质分裂的机制。我们正在使用蛋白质组学和比较基因组学技术来确定特定细胞周期阶段所需的蛋白质。通过分析不同细胞周期阶段的蛋白质组成，可以通过精确定位特定细胞周期阶段的蛋白质来更好地理解细胞分裂的机制。