INGTEGRATING BIOMATERIALS & BIOPHOTONICS TO ASSESS ECM MECHANICS

整合生物材料

• 批准号: 8170961
• 负责人: Elliot Lawrence Botvinick
• 金额: $ 1.49万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8170961
• 关键词: Biocompatible Materials; Biophotonics; Cells; Computer Retrieval of Information on Scientific Projects Database; Computer software; Engineering; Environment; Extracellular Matrix; Fiber; Funding; Goals; Grant; Institution; Mechanics; Research; Research Personnel; Resources; Source; Time; Tissues; United States National Institutes of Health

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The major goals of this project are to correlate bulk tissue mechanics with local micro-environment mechanics in engineered ECM tissues. specific use at LFD - Use of reflection confocal and SIM-FCS software to look at correlations along and between fibers, as well as matrix deformation by cells over time.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 该项目的主要目标是将工程化ECM组织中的局部微环境力学与大块组织力学相关联。 LFD的具体用途-使用反射共焦和SIM-FCS软件来观察沿着纤维和纤维之间的相关性，以及细胞随时间的基质变形。