IN VIVO CLINICAL RAMAN SPECTROSCOPY OF BREAST CANCER

乳腺癌体内临床拉曼光谱

• 批准号: 8170392
• 负责人: ZOYA VOLYNSKAYA
• 金额: $ 2.85万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8170392
• 关键词: Algorithms; Clinic; Clinical; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Data; Foundations; Freezing; Funding; Goals; Grant; Institution; Investigation; Mastectomy; Operative Surgical Procedures; Patients; Raman Spectrum Analysis; Research; Research Personnel; Resources; Source; Techniques; Tissues; United States National Institutes of Health; breast cancer diagnosis; breast lesion; in vivo; malignant breast neoplasm; time use

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Previous results from fresh-frozen tissue has demonstrated that Raman spectroscopy accurately classifies breast lesions and supports moving this technique to a clinical setting for further investigation of its efficacy in breast cancer diagnosis. As a result, we pursued clinical study. We collected Raman spectroscopic data in the operative room of the Cleveland Clinic Foundation from 9 patients undergoing partial mastectomy and mastectomy surgery. The main goal of this study is to detect status of margins in real-time using previously developed and prospectively validated chemico-morphological algorithm.

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