CLINICAL RAMAN INSTRUMENT

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 我们研究了拉曼光谱技术在动脉粥样硬化和乳腺癌诊断中的应用。多年来，我们成功地进行了多项体内和体外临床研究。我们能够利用拉曼光纤探头将我们基于显微镜的实验室系统最小化为临床拉曼系统。目前，我们正在开发一种迷你拉曼临床仪器，将向LBRC以外的用户提供。这个项目的目的是促进光学光谱学的临床转化研究；并使年轻/新的研究人员熟悉诊断光谱学的方法。LBRC将提供拉曼光谱仪器，能够在指纹范围(600-1800厘米-1)内收集生物组织的拉曼光谱。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have investigated the usage of Raman spectroscopy to diagnose atherosclerosis and breast cancer. Over the years, we have successfully conducted several in vivo and ex vivo clinical studies. We were able to minimize our microscopy-based laboratory system into a clinical Raman system utilizing a Raman fiber optical probe. Currently, we are developing a mini-Raman clinical instrument that will be available for users outside of the LBRC. The purposes of this project are to foster clinical translational research in optical spectroscopy; and to familiarize young/new investigators with the methods of diagnostic spectroscopy. The LBRC will provide Raman spectroscopy instrument capable of collecting Raman spectra from biological tissues over the fingerprint range (600-1800cm-1).