PENN STATE CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE

宾夕法尼亚州立大学临床与转化科学研究所

• 批准号: 8365251
• 负责人: Lawrence I Sinoway
• 金额: $ 305.12万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365251
• 关键词: Clinical Sciences; Institutes; Translational Research

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. This is the second resubmission application for a Clinical and Translational Science Award. We describe Penn State University's plan to transform our health research and education enterprise through the work of the Penn State Clinical and Translational Science Institute (CTSI). Throughout the University, the CTSI initiative has been greeted with great enthusiasm, broad support across colleges and campuses, and reaffirmation of our responsibility as a land grant University. The overarching goal of the Penn State CTSI is an engaged and responsive health science research and education enterprise that delivers on the promise of improved health. Starting with unique strengths in relevant biological, social and physical sciences, a culture and organizational structure that encourages collaboration across units, a tradition of engaging in problem-driven research, and strong connections to communities throughout Pennsylvania, we plan to achieve this by: 1) bolstering community alliances to strengthen trust, enhance awareness of disparities and ascertain needs; 2) cultivating new problem-driven interdisciplinary collaborations that go well beyond the traditional boundaries of biomedicine to address these needs, including partnering with industry; 3) sharing resources and promoting their most proficient use; 4) capitalizing on novel tools in information technology to collect, share and mine data, anci disseminate new knowledge; and 5) educating a new generation of investigators, health professionals and community leaders who are fluent across disciplines, aware of ethical principles, sensitive to the community's needs, and able to apply their skills in partnership with others. Penn State has a rich track record of breaking down barriers and of strong support for interdisciplinary collaboration, and has committed major resources to the CTSI. In this amended application, a new leadership team in biomedical informatics has been empowered to expand infrastructure and develop new software solutions to study genetics, epigenetics and systems biology. The University has increased its already substantial health science investment in transformational technologies, innovative educational programs, and major interdisciplinary pilot project programs. Jointly with our community partners, and through the CTSA consortium, the Penn State CTSI will serve as a collaborative engine that will drive research initiatives geared to enhance wellness and better predict, preempt and treat disease in the people we serve.RELEVANCE (See instructions); This proposal describes the newly created Penn State Clinical and Translational Science Institute (CTSI). The overarching goal of our CTSI initiative is to revitalize the health science research and education enterprise at our University to better enable it to deliver on the promise of improved health.

该子项目是对CTSA供资的百分比的估计， 用于广泛的研究领域（艾滋病研究，儿科研究，或 临床试验）。 列出的总成本仅为CTSA金额的估算 基础设施走向这一领域的研究，而不是直接提供资金， 向子项目或子项目工作人员提供NCRR补助金。 这是临床和转化科学奖的第二次重新提交申请。我们描述了宾夕法尼亚州立大学的计划，通过宾夕法尼亚州立大学临床和转化科学研究所（CTSI）的工作，改变我们的健康研究和教育企业。在整个大学，CTSI倡议已与极大的热情，在学院和校园的广泛支持，并重申我们作为一个赠地大学的责任迎接。宾州州立大学CTSI的总体目标是一个参与和响应健康科学研究和教育企业，提供改善健康的承诺。从相关生物，社会和物理科学的独特优势开始，鼓励跨单位合作的文化和组织结构，参与问题驱动研究的传统，以及与整个宾夕法尼亚州社区的紧密联系，我们计划通过以下方式实现这一目标：1）支持社区联盟，以加强信任，提高对差异的认识并确定需求; 2）培养新的问题驱动的跨学科合作，远远超出了传统的生物医学的界限，以满足这些需求，包括与工业界合作; 3）共享资源，并促进其最熟练的使用; 4）利用信息技术中的新工具来收集，共享和挖掘数据，并传播新知识;以及5）教育新一代的调查人员、卫生专业人员和社区领袖，他们精通各个学科，了解道德原则，对社区的需要敏感，并能够与他人合作运用他们的技能。宾州州立大学在打破障碍和大力支持跨学科合作方面有着丰富的记录，并为CTSI投入了大量资源。在此修订的应用程序中，生物医学信息学的新领导团队已被授权扩展基础设施并开发新的软件解决方案，以研究遗传学，表观遗传学和系统生物学。该大学已经增加了在转型技术，创新教育计划和重大跨学科试点项目计划方面的大量健康科学投资。与我们的社区合作伙伴一起，并通过CTSA联盟，宾州州立大学CTSI将作为一个合作引擎，将推动研究计划，以提高健康和更好地预测，先发制人，并在我们所服务的人治疗疾病。相关性（见说明）;本提案介绍了新成立的宾州州立大学临床和转化科学研究所（CTSI）。我们的CTSI计划的总体目标是振兴我们大学的健康科学研究和教育事业，以更好地使其能够实现改善健康的承诺。