PENN STATE CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE

宾夕法尼亚州立大学临床与转化科学研究所

• 批准号: 8365251
• 负责人: Lawrence I Sinoway
• 金额: $ 305.12万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365251
• 关键词: Clinical Sciences; Institutes; Translational Research

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. This is the second resubmission application for a Clinical and Translational Science Award. We describe Penn State University's plan to transform our health research and education enterprise through the work of the Penn State Clinical and Translational Science Institute (CTSI). Throughout the University, the CTSI initiative has been greeted with great enthusiasm, broad support across colleges and campuses, and reaffirmation of our responsibility as a land grant University. The overarching goal of the Penn State CTSI is an engaged and responsive health science research and education enterprise that delivers on the promise of improved health. Starting with unique strengths in relevant biological, social and physical sciences, a culture and organizational structure that encourages collaboration across units, a tradition of engaging in problem-driven research, and strong connections to communities throughout Pennsylvania, we plan to achieve this by: 1) bolstering community alliances to strengthen trust, enhance awareness of disparities and ascertain needs; 2) cultivating new problem-driven interdisciplinary collaborations that go well beyond the traditional boundaries of biomedicine to address these needs, including partnering with industry; 3) sharing resources and promoting their most proficient use; 4) capitalizing on novel tools in information technology to collect, share and mine data, anci disseminate new knowledge; and 5) educating a new generation of investigators, health professionals and community leaders who are fluent across disciplines, aware of ethical principles, sensitive to the community's needs, and able to apply their skills in partnership with others. Penn State has a rich track record of breaking down barriers and of strong support for interdisciplinary collaboration, and has committed major resources to the CTSI. In this amended application, a new leadership team in biomedical informatics has been empowered to expand infrastructure and develop new software solutions to study genetics, epigenetics and systems biology. The University has increased its already substantial health science investment in transformational technologies, innovative educational programs, and major interdisciplinary pilot project programs. Jointly with our community partners, and through the CTSA consortium, the Penn State CTSI will serve as a collaborative engine that will drive research initiatives geared to enhance wellness and better predict, preempt and treat disease in the people we serve.RELEVANCE (See instructions); This proposal describes the newly created Penn State Clinical and Translational Science Institute (CTSI). The overarching goal of our CTSI initiative is to revitalize the health science research and education enterprise at our University to better enable it to deliver on the promise of improved health.

该子项目代表了 CTSA 资金百分比的估计 被用于广泛的研究领域（艾滋病研究、儿科研究或 临床试验）。 列出的总成本只是 CTSA 金额的估计值 该研究领域的基础设施，而不是直接资助 NCRR 向子项目或子项目人员提供的补助金。 这是第二次重新提交临床和转化科学奖申请。我们描述了宾夕法尼亚州立大学通过宾夕法尼亚州立大学临床和转化科学研究所 (CTSI) 的工作来转变我们的健康研究和教育事业的计划。在整个大学，CTSI 倡议受到了学院和校园的极大热情和广泛支持，并重申了我们作为赠地大学的责任。宾夕法尼亚州立大学 CTSI 的总体目标是成为一家积极参与、反应迅速的健康科学研究和教育企业，兑现改善健康的承诺。从相关生物、社会和物理科学方面的独特优势、鼓励跨单位合作的文化和组织结构、参与问题驱动研究的传统以及与宾夕法尼亚州各地社区的牢固联系开始，我们计划通过以下方式实现这一目标：1）加强社区联盟，以加强信任，提高对差异的认识并确定需求； 2）培养新的问题驱动的跨学科合作，远远超出生物医学的传统界限，以满足这些需求，包括与工业界合作； 3）共享资源并促进其最有效的利用； 4）利用信息技术中的新工具来收集、共享和挖掘数据，传播新知识； 5) 教育新一代研究人员、卫生专业人员和社区领导者，他们精通跨学科、了解道德原则、对社区需求敏感，并能够与他人合作应用其技能。宾夕法尼亚州立大学在打破障碍和大力支持跨学科合作方面拥有丰富的记录，并向 CTSI 投入了大量资源。在这个修改后的申请中，生物医学信息学领域的新领导团队被授权扩展基础设施并开发新的软件解决方案来研究遗传学、表观遗传学和系统生物学。该大学增加了对转型技术、创新教育项目和重大跨学科试点项目的大量健康科学投资。宾夕法尼亚州立大学 CTSI 将与我们的社区合作伙伴一起，并通过 CTSA 联盟，充当协作引擎，推动旨在增强健康并更好地预测、预防和治疗我们所服务的人们的疾病的研究计划。该提案描述了新成立的宾夕法尼亚州立大学临床和转化科学研究所 (CTSI)。 CTSI 计划的总体目标是振兴我们大学的健康科学研究和教育事业，使其更好地兑现改善健康的承诺。