PENN STATE CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE

宾夕法尼亚州立大学临床与转化科学研究所

• 批准号: 8365251
• 负责人: Lawrence I Sinoway
• 金额: $ 305.12万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365251
• 关键词: Clinical Sciences; Institutes; Translational Research

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. This is the second resubmission application for a Clinical and Translational Science Award. We describe Penn State University's plan to transform our health research and education enterprise through the work of the Penn State Clinical and Translational Science Institute (CTSI). Throughout the University, the CTSI initiative has been greeted with great enthusiasm, broad support across colleges and campuses, and reaffirmation of our responsibility as a land grant University. The overarching goal of the Penn State CTSI is an engaged and responsive health science research and education enterprise that delivers on the promise of improved health. Starting with unique strengths in relevant biological, social and physical sciences, a culture and organizational structure that encourages collaboration across units, a tradition of engaging in problem-driven research, and strong connections to communities throughout Pennsylvania, we plan to achieve this by: 1) bolstering community alliances to strengthen trust, enhance awareness of disparities and ascertain needs; 2) cultivating new problem-driven interdisciplinary collaborations that go well beyond the traditional boundaries of biomedicine to address these needs, including partnering with industry; 3) sharing resources and promoting their most proficient use; 4) capitalizing on novel tools in information technology to collect, share and mine data, anci disseminate new knowledge; and 5) educating a new generation of investigators, health professionals and community leaders who are fluent across disciplines, aware of ethical principles, sensitive to the community's needs, and able to apply their skills in partnership with others. Penn State has a rich track record of breaking down barriers and of strong support for interdisciplinary collaboration, and has committed major resources to the CTSI. In this amended application, a new leadership team in biomedical informatics has been empowered to expand infrastructure and develop new software solutions to study genetics, epigenetics and systems biology. The University has increased its already substantial health science investment in transformational technologies, innovative educational programs, and major interdisciplinary pilot project programs. Jointly with our community partners, and through the CTSA consortium, the Penn State CTSI will serve as a collaborative engine that will drive research initiatives geared to enhance wellness and better predict, preempt and treat disease in the people we serve.RELEVANCE (See instructions); This proposal describes the newly created Penn State Clinical and Translational Science Institute (CTSI). The overarching goal of our CTSI initiative is to revitalize the health science research and education enterprise at our University to better enable it to deliver on the promise of improved health.

该子项目代表CTSA资金百分比的估计值 被用于广泛的研究领域（艾滋病研究，儿科研究或 临床试验）。 列出的总成本只是CTSA数量的估计值 基础设施朝向这一研究领域，而不是直接提供的资金 NCRR授予subproject或subproject人员。 这是临床和转化科学奖的第二次重新提交申请。我们描述了宾夕法尼亚州立大学通过宾夕法尼亚州立大学临床和转化科学研究所（CTSI）的工作来改变我们的健康研究和教育企业的计划。在整个大学中，CTSI倡议都充满热情，整个大学和校园的广泛支持，并重申我们作为土地赠款大学的责任。宾夕法尼亚州立大学CTSI的总体目标是一种参与且响应迅速的健康科学研究和教育企业，可实现改善健康的希望。从相关的生物学，社会和身体科学的独特优势开始，这种文化和组织结构鼓励跨单位合作，参与问题驱动的研究的传统以及与宾夕法尼亚州的整个社区的牢固联系，我们计划通过：1）实现这一目标：1）支持社区联盟以增强信任，增强对差异和确定性和确定性和确定性的认真性； 2）培养新的问题驱动的跨学科合作，远远超出了生物医学的传统界限，以满足这些需求，包括与行业合作； 3）共享资源并促进其最熟练的使用； 4）利用信息技术中的新工具来收集，共享和挖掘数据，ANCI传播新知识； 5）教育新一代的调查人员，卫生专业人员和社区领导者，他们能说出跨学科的流利，了解道德原则，对社区需求敏感，并能够与他人合作运用他们的技能。宾夕法尼亚州立大学（Penn State）拥有巨大的记录，即打破障碍和对跨学科合作的强烈支持，并为CTSI提供了主要资源。在此修订后的应用中，一支新的生物医学信息学领导团队已授权扩大基础设施并开发新的软件解决方案来研究遗传学，表观遗传学和系统生物学。该大学增加了已经在变革技术，创新的教育计划和主要跨学科的试点项目计划上的健康科学投资。宾夕法尼亚州立大学CTSI与我们的社区合作伙伴以及通过CTSA财团共同加入协作引擎，该引擎将推动旨在提高健康和更好地预测，在我们服务的人们中更好地预测，抢先和治疗疾病的研究举措（请参阅说明）；该建议描述了新创建的宾夕法尼亚州立大学临床和转化科学研究所（CTSI）。我们的CTSI计划的总体目标是振兴大学的健康科学研究和教育企业，以使其能够实现改善健康的希望。