Penn State Clinical and Translational Science Institute

宾夕法尼亚州立大学临床与转化科学研究所

• 批准号: 8916921
• 负责人: Lawrence I Sinoway
• 金额: $ 12.02万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2016-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8916921
• 关键词: Address; Applied Research; Award; Awareness; Basic Science; Biological Sciences; Biomedical Research; Clinical; Clinical Research; Clinical Sciences; Collaborations; Commit; Communication; Communication Methods; Communities; Community Health; Computer software; Coupled; Data; Data Set; Development; Discipline; Disease; Economically Deprived Population; Economics; Education; Elderly; Epigenetic Process; Ethical Issues; Ethics; Expenditure; Generations; Genes; Genetic; Goals; Grant; Health; Health Professional; Health Sciences; Health Services Research; Healthcare; Industry; Informatics; Information Technology; Institutes; Institution; Instruction; Investments; Knowledge; Leadership; Link; Measures; Medicine; Methods; Minority; Modeling; Monitor; Nafion; Outcome; Pennsylvania; Performance; Pilot Projects; Population; Process; Proteins; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Resource Sharing; Resources; Role; Rural; Science; Scientist; Services; Social Sciences; Societies; Solutions; Students; Support Groups; Systems Biology; Training; Translational Research; Translations; Trust; Universities; Vision; Work; biomedical informatics; career development; college; data mining; demographics; empowered; health science research; human disease; improved; industry partner; innovation; innovative technologies; interdisciplinary collaboration; interest; meetings; novel; novel strategies; organizational structure; outreach; physical science; preempt; prevent; programs; protocol development; racial and ethnic; skills; suburb; success; tool; trend; virtual

This is the second resubmission application for a Clinical and Translational Science Award. We describe Penn State University's plan to transform our health research and education enterprise through the work of the Penn State Clinical and Translational Science Institute (CTSI). Throughout the University, the CTSI initiative has been greeted with great enthusiasm, broad support across colleges and campuses, and reaffirmation of our responsibility as a land grant University. The overarching goal of the Penn State CTSI is an engaged and responsive health science research and education enterprise that delivers on the promise of improved health. Starting with unique strengths in relevant biological, social and physical sciences, a culture and organizational structure that encourages collaboration across units, a tradition of engaging in problem-driven research, and strong connections to communities throughout Pennsylvania, we plan to achieve this by: 1) bolstering community alliances to strengthen trust, enhance awareness of disparities and ascertain needs; 2) cultivating new problem-driven interdisciplinary collaborations that go well beyond the traditional boundaries of biomedicine to address these needs, including partnering with industry; 3) sharing resources and promoting their most proficient use; 4) capitalizing on novel tools in information technology to collect, share and mine data, anci disseminate new knowledge; and 5) educating a new generation of investigators, health professionals and community leaders who are fluent across disciplines, aware of ethical principles, sensitive to the community's needs, and able to apply their skills in partnership with others. Penn State has a rich track record of breaking down barriers and of strong support for interdisciplinary collaboration, and has committed major resources to the CTSI. In this amended application, a new leadership team in biomedical informatics has been empowered to expand infrastructure and develop new software solutions to study genetics, epigenetics and systems biology. The University has increased its already substantial health science investment in transformational technologies, innovative educational programs, and major interdisciplinary pilot project programs. Jointly with our community partners, and through the CTSA consortium, the Penn State CTSI will serve as a collaborative engine that will drive research initiatives geared to enhance wellness and better predict, preempt and treat disease in the people we serve.

这是第二次重新提交临床和转化科学奖申请。我们描述 宾夕法尼亚州立大学计划通过以下工作来转变我们的健康研究和教育事业 宾夕法尼亚州立大学临床与转化科学研究所 (CTSI)。在整个大学中，CTSI 该倡议得到了各学院和校园的极大热情和广泛支持， 重申我们作为赠地大学的责任。宾夕法尼亚州立大学 CTSI 的总体目标 是一家积极参与、反应迅速的健康科学研究和教育企业，致力于提供 改善健康的承诺。从相关生物、社会和物理方面的独特优势开始 科学、鼓励跨单位协作的文化和组织结构、传统 参与以问题为导向的研究，并与宾夕法尼亚州各地的社区建立牢固的联系，我们 计划通过以下方式实现这一目标： 1) 加强社区联盟，以加强信任，提高意识 差异并确定需求； 2）培养新的问题驱动的跨学科合作 远远超出生物医学的传统界限来满足这些需求，包括与 行业; 3）共享资源并促进其最有效的利用； 4）利用新工具 信息技术收集、共享和挖掘数据，ANCI传播新知识； 5）教育 新一代的调查人员、卫生专业人员和社区领袖能够流利地了解 遵守纪律，了解道德原则，对社区的需求敏感，并能够将自己的技能应用于 与他人的伙伴关系。宾夕法尼亚州立大学在打破障碍和强有力的支持方面拥有丰富的记录 致力于跨学科合作，并向 CTSI 投入了大量资源。在本次修订中 应用程序，一个新的生物医学信息学领导团队已被授权扩大基础设施 开发新的软件解决方案来研究遗传学、表观遗传学和系统生物学。大学有 增加了对转型技术、创新技术的本已大量的健康科学投资 教育计划和重大跨学科试点项目计划。与我们的社区一起 合作伙伴，并通过 CTSA 联盟，宾夕法尼亚州立大学 CTSI 将作为一个协作引擎， 将推动旨在增强健康并更好地预测、预防和治疗疾病的研究举措 我们服务的人们。