Penn State Clinical and Translational Science Institute

宾夕法尼亚州立大学临床与转化科学研究所

• 批准号: 8490522
• 负责人: Lawrence I Sinoway
• 金额: $ 410.83万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2016-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8490522
• 关键词: Address; Applied Research; Award; Awareness; Basic Science; Biological Sciences; Biomedical Research; Clinical; Clinical Research; Clinical Sciences; Collaborations; Commit; Communication; Communication Methods; Communities; Community Health; Computer software; Coupled; Data; Data Set; Development; Discipline; Disease; Economically Deprived Population; Economics; Education; Elderly; Epigenetic Process; Ethical Issues; Ethics; Expenditure; Generations; Genes; Genetic; Goals; Grant; Health; Health Professional; Health Sciences; Health Services Research; Healthcare; Industry; Informatics; Information Technology; Institutes; Institution; Instruction; Investments; Knowledge; Leadership; Link; Measures; Medicine; Methods; Minority; Modeling; Monitor; Nafion; Outcome; Pennsylvania; Performance; Pilot Projects; Population; Process; Proteins; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Resource Sharing; Resources; Role; Rural; Science; Scientist; Services; Social Sciences; Societies; Solutions; Students; Support Groups; Systems Biology; Training; Translational Research; Translations; Trust; Universities; Vision; Work; biomedical informatics; career development; college; data mining; demographics; empowered; health science research; human disease; improved; industry partner; innovation; innovative technologies; interdisciplinary collaboration; interest; meetings; novel; novel strategies; organizational structure; outreach; physical science; preempt; prevent; programs; protocol development; racial and ethnic; skills; suburb; success; tool; trend; virtual

This is the second resubmission application for a Clinical and Translational Science Award. We describe Penn State University's plan to transform our health research and education enterprise through the work of the Penn State Clinical and Translational Science Institute (CTSI). Throughout the University, the CTSI initiative has been greeted with great enthusiasm, broad support across colleges and campuses, and reaffirmation of our responsibility as a land grant University. The overarching goal of the Penn State CTSI is an engaged and responsive health science research and education enterprise that delivers on the promise of improved health. Starting with unique strengths in relevant biological, social and physical sciences, a culture and organizational structure that encourages collaboration across units, a tradition of engaging in problem-driven research, and strong connections to communities throughout Pennsylvania, we plan to achieve this by: 1) bolstering community alliances to strengthen trust, enhance awareness of disparities and ascertain needs; 2) cultivating new problem-driven interdisciplinary collaborations that go well beyond the traditional boundaries of biomedicine to address these needs, including partnering with industry; 3) sharing resources and promoting their most proficient use; 4) capitalizing on novel tools in information technology to collect, share and mine data, anci disseminate new knowledge; and 5) educating a new generation of investigators, health professionals and community leaders who are fluent across disciplines, aware of ethical principles, sensitive to the community's needs, and able to apply their skills in partnership with others. Penn State has a rich track record of breaking down barriers and of strong support for interdisciplinary collaboration, and has committed major resources to the CTSI. In this amended application, a new leadership team in biomedical informatics has been empowered to expand infrastructure and develop new software solutions to study genetics, epigenetics and systems biology. The University has increased its already substantial health science investment in transformational technologies, innovative educational programs, and major interdisciplinary pilot project programs. Jointly with our community partners, and through the CTSA consortium, the Penn State CTSI will serve as a collaborative engine that will drive research initiatives geared to enhance wellness and better predict, preempt and treat disease in the people we serve.

这是临床和转化科学奖的第二次重新提交申请。我们描述 宾夕法尼亚州立大学计划通过以下工作来改变我们的健康研究和教育事业： 宾夕法尼亚州立大学临床和转化科学研究所（CTSI）。在整个大学，CTSI 倡议受到了极大的热情，在学院和校园的广泛支持， 重申我们作为一所赠地大学的责任。宾州州立大学CTSI的首要目标是 是一个积极参与和响应健康科学研究和教育企业，提供 改善健康的承诺。从相关的生物、社会和身体方面的独特优势开始 科学，鼓励跨单位合作的文化和组织结构， 从事问题驱动的研究，并与整个宾夕法尼亚州的社区建立了密切的联系，我们 计划通过以下方式实现这一目标：1）支持社区联盟，以加强信任，提高对 差异和确定需求; 2）培养新的问题驱动的跨学科合作， 远远超出了生物医学的传统界限，以满足这些需求，包括与 3）共享资源并促进其最熟练的使用; 4）利用新的工具， 利用信息技术收集、分享和挖掘数据，传播新知识; 5）教育 新一代的调查人员，卫生专业人员和社区领导人，他们精通 纪律，意识到道德原则，对社区的需求敏感，并能够运用他们的技能， 与他人的伙伴关系。宾州州立大学在打破障碍和强有力的支持方面有着丰富的记录 为跨学科合作，并已承诺的CTSI的主要资源。在此修正 应用程序，生物医学信息学的新领导团队已被授权扩展基础设施 并开发新的软件解决方案来研究遗传学、表观遗传学和系统生物学。该大学 增加了对转型技术、创新技术和创新技术的大量健康科学投资， 教育项目和重大跨学科试点项目。与我们的社区一起 合作伙伴，并通过CTSA财团，宾州州立大学CTSI将作为一个合作引擎， 将推动研究计划，以提高健康和更好地预测，先发制人和治疗疾病， 我们所服务的人民。