AIM 2012 Conference

描述(申请人提供)：共济失调，一种致残性和经常致命的神经疾病，由广泛的后天和遗传侮辱引起。第四届共济失调研究人员会议，AIM2012，将召集一个国际科学研究人员名册，以解决共济失调的多学科性质，更好地确定共济失调的致病基础，并探索治疗这种基本上无法治疗的疾病的方法。会议将集中讨论最新的科学进展和新出现的治疗转化方法，目的是实现以下五个目标：1)加强与共济失调研究有关的开放信息交流；2)促进世界各地研究人员之间的合作研究；3)提高我们对人类共济失调的了解；4)建立共同调查和存储与共济失调及其治疗有关的数据的国际协议；5)为初级研究人员提供一个机会，介绍他们的工作，与 更多该领域的知名科学家，并有机会与患者和支持团体互动，使他们能够看到他们工作的临床影响和重要性。AIM2012将是促进共济失调研究和治疗方法的合作和讨论的关键机制，由于该领域正在美国和欧洲进入有意义的多中心临床试验阶段，这一点尤其重要。AIM2012会议在德克萨斯州圣安东尼奥举行，与美国最大的共济失调基金会的年度会议相吻合，将最大限度地发挥这次会议对科学家和患者的影响。 与公共卫生相关：AIM2012第四届共济失调研究会议(AIM2012)将聚焦于共济失调研究和治疗方法的最新进展。共济失调被定义为运动控制的丧失，可影响人类运动步态、灵巧度、言语、吞咽和眼球运动的方方面面，全世界每2000人中约有1人患有共济失调。对共济失调的遗传学理解的不断涌现，最近促使研究人员设想了共同的致病机制和可能的共同治疗方法。疾病目标和治疗策略中的这些新概念要求科学家和临床医生之间加强沟通和合作，以便能够开发治疗方法，这是第四次共济失调调查会议的主要目标。这次会议还将提供一个论坛，为这一研究领域招募新的研究人员，这是取得迅速成功的关键因素，治疗这些疾病的可能性似乎越来越大。

DESCRIPTION (provided by applicant): Ataxia, a disabling and frequently fatal neurological disorder, is caused by a wide range of acquired and genetic insults. The Fourth Ataxia Investigators' Meeting, AIM2012, will assemble an international roster of scientific investigators to address the multi-disciplinary nature of ataxia, to define better the pathogenic basis of ataxia and to explore routes to therapy for what is largely an untreatable disease. The conference will focus on the most recent scientific advances and emerging translational approaches toward therapy, with the objective of achieving the following five goals: 1) Enhance the open exchange of information related to ataxia research; 2) Stimulate collaborative research between investigators worldwide; 3) Improve our understanding of human ataxic disorders; 4) Establish international protocols for the common investigation and storage of data related to ataxia and its treatment; 5) Provide junior investigators with an opportunity to present their work, interact with more established scientists in the field, and have an opportunity to interact with patients and support groups so that they can see the clinical impact and importance of their work. AIM2012 will represent a critical mechanism to facilitate collaboration and discussion on ataxia research and therapeutic approaches, which is of particularly great importance now that the field is entering the phase of meaningful, multi-center clinical trials both in the United States and Europe. The location of the AIM2012 meeting in San Antonio, Texas, dovetailing with the annual meeting of the largest ataxia foundation in the country, will maximize the impact of this meeting for both scientists and patients alike. PUBLIC HEALTH RELEVANCE: The AIM2012 Fourth Ataxia Investigators' Meeting (AIM2012) will focus on the most recent advances in ataxia research and therapeutic approaches for ataxic disorders. Ataxia, which is defined as the loss of motor control, can affect all aspects of human movement gait, dexterity, speech, swallowing, and eye movements, and afflicts approximately 1 in every 2,000 individuals worldwide. Emerging genetic understanding of ataxias has recently led investigators to envision common pathogenic mechanisms and possible shared therapeutic approaches. These new concepts in disease targets and therapeutic strategy demand increased communication and collaboration among scientists and clinicians so that therapies can be developed, which is a primary goal of the 4th Ataxia Investigators' Meeting. This meeting will also provide a forum for recruiting new investigators to this field of research, which is a critically important element for achieving the rapid success that appears increasingly possible for treating these diseases.