Michigan Alzheimer's Disease Research Center-Supplement

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ABSTRACT Health disparities in ADRD continue to be a major social and health justice challenge that affect the most vulnerable population in the USA. The fact that Black / African Americans and Latinos are more likely to not receive a dementia diagnosis and experience discrimination when visiting a physician indicates that disparity in ADRDs may be greater than estimated. The Michigan Alzheimer’s Disease Research Center (Michigan ADRC) was refunded in September 2021 as a tri-university consortium that brings together the three major research universities in Michigan to create a novel statewide initiative: University of Michigan (U-M), Michigan State University (MSU) and Wayne State University (WSU). The scope of this proposal remains well within the Michigan ADRC’s goal to “Foster, Catalyze and Perform Research of the Highest Potential Impact in AD and Related Neurodegenerative Disorders” and specifically for the Michigan ADRC’s Clinical Core aim to “Enhance Diversity in Aging and Dementia Research.” Building on our success, we will establish a Latino Cohort remote enrollment site in Grand Rapids, Michigan. To achieve this goal, we propose to 1) leverage established community partnerships to address health disparities in ADRD through the training of community health workers and personnel at community healthcare clinics about early signs of cognitive impairment, 2) increase participation of community dwelling older Latino adults in ADRD research, 3) profile plasma biomarker of community dwelling older Latino adults with and without cognitive impairment. The ultimate goal is to establish a representative Latino Cohort that enhances the geographical representation of Latinos in ADRD research. Importantly, using a Health Equity Framework, we will establish a community dwelling older Latino cohort while enhancing resources and access to healthcare within underserved communities and create a critically important statewide dementia-focused resource that serves researchers, trainees, health care professionals and the public.