Alcohol and Depression among Middle-Aged and Older Adults

中老年人的酒精与抑郁症

• 批准号: 8191808
• 负责人: MICHAEL T WINDLE
• 金额: $ 22.28万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-10 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8191808
• 关键词: Address; Adolescent; Adolescent Risk Behavior; Adult; Alcohol consumption; Alcohol dependence; Alcoholism; Alcohols; Characteristics; Child; Conflict (Psychology); Couples; Data; Data Analyses; Disease; Elderly; Emotions; Family; Family history of; Fathers; Female; Grant; Growth; Health; Husband; Income; Influentials; Interview; Joints; Linear Models; Longevity; Mails; Major Depressive Disorder; Measurement; Medical; Mental Depression; Mental Health; Modeling; Mothers; Outcome; Outcome Measure; Parents; Pattern; Phase; Population; Problem Solving; Prospective Studies; Public Health; Research; Risk; Risk Factors; Role; Sampling; Sex Characteristics; Statistical Models; Stressful Event; Surveys; Time; Time Study; Twin Multiple Birth; Wife; Withdrawal; Woman; aged; alcohol epidemiology; chronic alcohol ingestion; conflict resolution; coping; cost effective; depressive symptoms; drinking; follow-up; interpersonal conflict; male; men; middle age; offspring; parental alcoholism; parental role; prospective; response; satisfaction; skills; trend; young adult

DESCRIPTION (provided by applicant): This revised application seeks to prospectively study alcohol and depression among middle- aged and older adults. Secondary data analyses of extant three-wave, 10-year prospective data (baseline and two successive five-year follow-up points) from the Lives across Time (LAT) Study are proposed using the parent data from the LAT. A total of 1,532 parents participated at least once across the three-waves, with 80% participating at 2-3 waves. Among these parents are 400 marital couples. The focus of the application is threefold. First, the stability and change of alcohol and depression will be studied across time via different statistical models (e.g., latent growth models) to evaluate how both may change and if change in one (e.g., alcohol use) is significantly related to change in the other (e.g., depression). Second, several important factors will be investigated with regard to their prediction of initial levels and changes in alcohol and depression across time. These will include general coping styles (problem-focused coping; emotion-focused coping), coping drinking motives, and family history of alcoholism and depression. Third, interpersonal factors (support and conflict) and conflict resolution styles (positive problem solving, conflict engagement) will be investigated in relation to alcohol use and depressive symptom trajectories and alcohol and major depressive disorders. Couples analyses will be conducted to address similar issues for the martial dyads, as well as to evaluate how alcohol and depression among marital partners may influence changes in marital satisfaction. A range of longitudinal models (e.g., dual latent growth models, dual latent class group trajectory models) will be used to analyze the data and evaluate sex differences in trajectories, antecedents, and outcomes. PUBLIC HEALTH RELEVANCE: Demographic trends in the U.S. indicate that the proportion of middle-aged and older adults is increasing, with the population aged >65 years projected to increase from 12.4% in 2000 to 19.6% in 2030. Associated with the expansion of this segment of the population are increased demands on the medical and public health sectors to address health conditions, including alcohol use and depression. This application proposes to use three-wave, 10-year prospective data of 1,532 adults, including 400 marital couples, to evaluate potentially important modifiable characteristics (e.g., coping styles, conflict resolution skills) that prospectively predict alcohol, depression, and their co-occurrence.

描述（由申请人提供）：这份修订后的申请旨在前瞻性地研究中老年人的酒精和抑郁症。建议使用LAT的母数据对来自不同时间段生命（LAT）研究的现有三波、10年前瞻性数据（基线和两个连续的5年随访点）进行次要数据分析。共有1，532名家长在三波中至少参加了一次，其中80%参加了2-3波。在这些父母中有400对已婚夫妇。应用程序的重点是三方面的。首先，将通过不同的统计模型（例如，潜在增长模型）来评估两者如何改变以及是否在一个中改变（例如，酒精使用）与另一种变化显着相关（例如，抑郁症）。其次，将研究几个重要因素，以预测酒精和抑郁症的初始水平和变化。这些将包括一般应对方式（以问题为中心的应对;以情绪为中心的应对），应对饮酒动机，以及酗酒和抑郁的家族史。第三，人际因素（支持和冲突）和冲突解决方式（积极解决问题，冲突参与）将调查有关酒精使用和抑郁症状轨迹和酒精和重度抑郁症。夫妻分析将进行，以解决类似的问题，为军事二人组，以及评估如何酒精和抑郁症的婚姻伴侣可能会影响婚姻满意度的变化。一系列纵向模型（例如，双潜在增长模型，双潜在类组轨迹模型）将用于分析数据，并评估轨迹，前因和结果的性别差异。 公共卫生关系：美国的人口趋势表明，中年和老年人的比例正在增加，预计65岁以上的人口将从2000年的12.4%增加到2030年的19.6%。随着这部分人口的扩大，对医疗和公共卫生部门的需求也在增加，以解决健康问题，包括酗酒和抑郁症。本申请建议使用1，532名成年人（包括400对夫妻）的三波10年前瞻性数据，以评估潜在的重要可修改特征（例如，应对方式，解决冲突的技能），前瞻性地预测酒精，抑郁症，以及它们的共同发生。