Histiocyte Society Annual Meeting to be Held in Boston

组织细胞学会年会将于波士顿举行

• 批准号: 8062830
• 负责人: Alexandra H Filipovich
• 金额: $ 1万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-02-01 至 2012-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8062830
• 关键词: Adult; Basic Science; Biology; Boston; Businesses; Child; Clinical; Clinical Research; Clinical Trials; Clinical Trials Data Monitoring Committees; Dendritic Cells; Development; Disease; Education; Family; Functional disorder; Healthcare Systems; Hematology; Histiocytosis; Homeostasis; Human; Immune; Immunology; Interest Group; International; Internet; Knowledge; Medical; Mentors; Mononuclear; Non-Malignant; Orphan Disease; Patient Representative; Patients; Persons; Publications; Research; Scientist; Societies; Solutions; System; Treatment outcome; Work; abstracting; clinical care; cost; follow-up; histiocyte; improved; macrophage; meetings; member; older patient; posters; programs

DESCRIPTION (provided by applicant): The Histiocytoses are rare non-malignant disorders of the mononuclear phagocytic system. The pathophysiology of many of these diseases is unknown and, in the case of the widely- disseminated and potentially fatal forms, treatments to date have been variably effective and sometimes highly toxic. Histiocytoses meet criteria for designation as orphan diseases. The Histiocyte Society, founded 26 years ago, is the unique international organization of clinicians and scientists focused on expanding knowledge about these diseases and improving treatment outcomes. A major focus of activities is the annual meeting which changes venues around the world. The scientific agenda includes presentations by invited speakers regarding the most recent developments in the biology of histiocytic disorders, as well as topics in more basic hematology and immunology related to the development of macrophages and dendritic cells, and mechanisms of immune homeostasis. The program also has several platform sessions and a moderated poster presentation of selected abstracts which have been scored by the Educational Committee of the society. Additionally, the meeting allows for face to face meetings of the Executive Board of the society, the Educational and Scientific committees, LCH and HLH Disease Interest Groups, and clinical study groups that manage the society-sponsored clinical trials, and the Data Safety Monitoring Board. PUBLIC HEALTH RELEVANCE: The Histiocytic Disorders, while individually rare, as a group represent a significant burden to the health care system due to the complexity and cost of managing children with such disorders. Adult patients with histiocytosis are particularly underserved. Treatments which are effective in children are often too toxic for older patients. The Histiocyte Society annual meetings are the only opportunity to gather medical practitioners from around the world working together to advance knowledge which leads to improved treatment outcomes in these patients.

描述（申请人提供）：组织细胞病是罕见的单核吞噬系统的非恶性疾病。其中许多疾病的病理生理学尚不清楚，对于广泛传播和可能致命的形式，迄今为止的治疗方法效果不一，有时毒性很大。组织细胞增多症符合孤儿病的标准。组织细胞学会成立于26年前，是一个由临床医生和科学家组成的独特的国际组织，致力于扩大对这些疾病的认识并改善治疗结果。活动的一个主要焦点是在世界各地改变地点的年度会议。科学议程包括由特邀演讲者介绍组织细胞疾病生物学的最新进展，以及与巨噬细胞和树突状细胞发展有关的更基本的血液学和免疫学主题，以及免疫稳态机制。该计划还包括几个平台会议和由社会教育委员会评分的精选摘要的主持海报展示。此外，会议还允许协会执行委员会、教育和科学委员会、LCH和HLH疾病兴趣小组、管理协会赞助的临床试验的临床研究小组和数据安全监测委员会的面对面会议。