International Symposium on Collaterals to the Brain

大脑络脉国际研讨会

• 批准号: 8458827
• 负责人: DAVID SIGMUND LIEBESKIND
• 金额: $ 1万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-30 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8458827
• 关键词: Acute; Acute Disease; Address; Adult; Anatomy; Area; Attention; Blood Vessels; Blood flow; Books; Brain; Brain Diseases; Cerebrovascular Circulation; Chronic; Clinical; Clinical Trials; Clinical Trials Design; Collaborations; Collateral Circulation; Development; Diagnosis; Disabled Persons; Disease; Education; Ensure; Evaluation; Event; Fertilization; Functional disorder; Future; Genetic; Goals; Health; Hemorrhage; Image; Infarction; Influentials; International; Ischemia; Ischemic Stroke; Journals; Knowledge; Mainstreaming; Measurable; Mentors; Methodology; Minority; National Institute of Neurological Disorders and Stroke; Outcome; Participant; Perfusion; Plant Roots; Postdoctoral Fellow; Prevention; Progress Review Group; Public Health; Publications; Publishing; Questionnaires; Recording of previous events; Request for Proposals; Research; Research Personnel; Research Priority; Risk; Role; Stenosis; Stroke; Structure; Students; Therapeutic; Translational Research; United States National Institutes of Health; Woman; Work; acute stroke; base; brain tissue; career; clinical practice; design; disability; hemodynamics; improved; innovation; insight; interdisciplinary approach; lectures; meetings; multidisciplinary; next generation; novel; outcome forecast; parity; programs; stroke recovery; success; symposium

DESCRIPTION (provided by applicant): The International Symposium on Collaterals to the Brain is a multidisciplinary scientific conference focused on collateral perfusion in acute and chronic neurovascular disorders. This proposal requests partial support for a conference with broad, long-term objectives that will detail current status of knowledge on collaterals, identify gaps, and develop a roadmap for the next 5 years of research in this field. Mentoring junior investigators in this endeavor is a major emphasis of this first meeting devoted to collaterals to the brain. Collaterals have recently become a mainstream focus of stroke research, yet a forum has never been established to dedicate attention to this top research priority of NINDS. The aims of this conference will convene over 30 leading experts to cover critical aspects of this burgeoning field, with a total of 200 participants for a 2-day conference in an academic setting. The confirmed program is structured into 5 sessions covering the history and translational research on collaterals, chronic role of collaterals, imaging features, acute stroke aspects, and considerations of clinical trial design for collateral therapeutics. A seminar and panel discussion is devoted to issues germane to mentoring the next generation of investigators in collateral perfusion. Publication plans include a detailed roadmap on next steps in research on collaterals. Every effort will be made to encourage participation by postgraduate students and postdocs, to have parity in the numbers of women, and to include minorities and persons with disabilities. Measurable outcomes of conference goals will be assessed, evaluating the impact of this symposium on the NIH commitment to new investigators, translational stroke research and the NINDS PRG priority for studies on collateral perfusion. The significance of this proposal is underscored by the establishment of a framework for novel research collaborations, cultivation of new investigators and improved clinical practice in this area, through a unique event, associated interactions and subsequent roadmap publication. The health relatedness of this proposal is rooted in the discussions and research initiatives that will help address key prioritie on the influential role of collaterals in the devastating disorder of stroke. PUBLIC HEALTH RELEVANCE: The International Symposium on Collaterals to the Brain is a 2-day multidisciplinary scientific conference focused on collateral perfusion in acute and chronic neurovascular disorders. Leading experts will evaluate current knowledge on the role of collaterals, identify gaps, address mentoring issues of future innovators in this area, and publish a detailed roadmap for the next 5 years of research on collateral perfusion. Understanding the beneficial effects of collaterals in acute stroke and intracranial stenoses may accelerate the development of collateral therapeutics to restore blood flow in stroke, the leading cause of adult disability in the US and a key priority for improving public health.

描述(由申请人提供)：脑络脉国际研讨会是一个多学科的科学会议，重点是急慢性神经血管疾病的侧支血流灌注。这项提议要求部分支持一次具有广泛、长期目标的会议，该会议将详细说明络脉知识的现状，找出差距，并为该领域未来5年的研究制定路线图。在这一努力中指导初级研究人员是这次致力于大脑络脉的第一次会议的主要重点。近年来，络脉已成为中风研究的主流焦点，然而，从来没有建立一个论坛来关注NINDS的这一首要研究重点。本次会议的目标是召集30多名顶尖专家，讨论这一新兴领域的关键问题，共有200人参加，为期两天的学术会议。已确认的计划分为5个会议，涵盖络脉的历史和转译研究、络脉的慢性作用、影像特征、急性中风方面，以及络脉疗法临床试验设计的考虑。研讨会和小组讨论 致力于指导下一代研究人员在侧支灌流方面的相关问题。出版计划包括关于络脉研究下一步的详细路线图。将尽一切努力鼓励研究生和博士后参与，使妇女人数均等，并将少数群体和残疾人包括在内。将评估会议目标的可衡量结果，评估这次研讨会对NIH对新研究人员的承诺、转化性卒中研究以及NINDS PRG侧支灌流研究的优先顺序的影响。通过一次独特的活动、相关的互动和随后的路线图出版，为新的研究合作、培养新的研究人员和改善这一领域的临床实践建立了一个框架，突显了这一建议的重要性。这项建议的健康相关性植根于讨论和研究倡议，这些讨论和研究倡议将有助于解决侧支在破坏性中风障碍中的重要作用这一关键优先事项。 公共卫生相关性：脑络脉国际研讨会是一个为期两天的多学科科学会议，重点是急性和慢性神经血管疾病的侧支灌流。领先的专家将评估目前关于经络作用的知识，找出差距，解决这一领域未来创新者的指导问题，并发表 未来5年侧支血流灌注研究的详细路线图。了解络脉在急性中风和颅内狭窄中的有益作用可能会加速侧支疗法的发展，以恢复中风的血液流动，中风是美国成年人残疾的主要原因，也是改善公共健康的关键优先事项。