6th International Symposium on Collaterals to the Brain

第六届脑络国际研讨会

• 批准号: 9914738
• 负责人: DAVID SIGMUND LIEBESKIND
• 金额: $ 1.5万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-30 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9914738
• 关键词: Achievement; Acute; Address; Adult; Area; Automobile Driving; Award; Basic Science; Blood flow; Brain; Cerebral Ischemia; Clinical; Clinical Research; Collaborations; Collateral Circulation; Communication; Communities; Complement; Country; Data Analyses; Decision Making; Development; Devices; Diffusion; Disabled Persons; Educational workshop; Ensure; Evaluation; Exhibits; Faculty; Funding; Future; Goals; Hybrids; Image; Individual; International; Internet; Ischemia; Ischemic Stroke; Knowledge; Logistics; Measurable; Medical; Mentors; Methods; Mission; Modeling; National Institute of Neurological Disorders and Stroke; Nature; Outcome; Paper; Participant; Persons; Precision Medicine Initiative; Public Health; Publications; Publishing; Questionnaires; Recovery; Request for Proposals; Research; Research Personnel; Resources; Role; Science; Secure; Series; Site; Stream; Stroke; Stroke prevention; Structure; Surveys; Technology; Therapeutic; Time; TimeLine; Translating; Translational Research; Translations; Triage; Underrepresented Minority; United States National Institutes of Health; Vascular Cognitive Impairment; Woman; base; burden of illness; care systems; cerebral hemodynamics; clinical implementation; clinically relevant; data sharing; disability; education resources; ethnic minority population; experience; hemodynamics; improved; innovation; meetings; member; mobile computing; multidisciplinary; nervous system disorder; neurovascular; novel; outreach; parity; posters; precision medicine; programs; racial and ethnic; recruit; stroke education; stroke therapy; success; symposium; technological innovation; treatment strategy; virtual; web site; webinar

PROJECT SUMMARY/ABSTRACT The 6th International Symposium on Collaterals to the Brain is a multidisciplinary scientific conference focused on collateral circulation in ischemic stroke. This proposal requests partial support for a conference with broad, long-term objectives that will advance current research on collateral blood flow and identify gaps in current treatment strategies around the world. The collaterome, or individual capacity to offset ischemia in the brain, and determination of a favorable collateral profile have become pivotal factors in the consideration of cerebral ischemia and the precision medicine of stroke driving individualized medical decision-making. The conference directly addresses the most pressing issues and gaps in optimally defining collateral status that limit realization of stroke therapies around the world. Decisive challenges include generalizability of optimal triage and selection paradigms based on collateral status for definitive treatment of ischemic stroke, rapid dissemination of expert methods and transformative advances, and the urgent need to leverage networking opportunities for stroke education and science related to the hemodynamics of collaterals to the brain. The aims of this conference will convene faculty from around the world to connect on-site participants at the state-of-the-art facility with remote audiences in more than 50 countries and regions. Detailed presentation topics have been arranged around themes relating to the basic science, translational, clinical research, routine clinical aspects, imaging, endovascular therapy and systems of care issues of collaterals in the brain. The confirmed program of this 2½-day conference is structured into 40-minute sessions devoted to key issues in translating the collaterome in stroke therapy across the globe. Of particular importance is the interval progress on the use of hemodynamics in stroke that will be presented based on the country-based surveys developed in 2018. The moderated poster session, hands on neurovascular device workshop and interspersed networking opportunities will enhance collaborative initiatives in this burgeoning field. Rapid dissemination of electronic posters, proceedings and other publications, as in past meetings, will intensify the impact of this unique and esteemed annual Symposium. Dedicated efforts for appropriate representation have already been delineated to have parity in the numbers of women, recruit underrepresented minorities and persons with disabilities, culminating in an extremely diverse spectrum of participants. Trainee awards for underrepresented minorities from the local region will markedly enhance the educational impact of this meeting. Measurable outcomes will quantify the impact of this symposium on the NINDS mission to enhance knowledge of collaterals and reduce the burden of neurological disease due to stroke. This unique forum of expertise extending from a state-of-the- art venue across the world emphasizes the timely impact of collaterals on a monumental scale, encouraging maximal participation, rapid diffusion and added value of networking resource.

项目总结/摘要 第六届国际学术研讨会对大脑是一个多学科的科学会议，重点 对缺血性中风侧支循环的影响这一建议要求部分支持召开一次广泛的会议， 长期目标，这将推动目前的研究侧支血流，并确定目前的差距， 世界各地的治疗策略。collaterome，或个人能力，以抵消缺血的大脑， 和确定有利的侧支轮廓已经成为考虑脑血管疾病的关键因素。 缺血和中风的精准医疗推动个体化医疗决策。会议 直接解决了最紧迫的问题和差距，在最佳定义抵押品的地位，限制实现 中风治疗的例子。决定性的挑战包括最佳分诊的普遍性， 基于侧支状态的缺血性卒中确定性治疗的选择范例，快速传播 专家方法和变革性进展，迫切需要利用网络机会， 中风教育和科学有关的血流动力学的络脉到大脑。其目的是 会议将召集来自世界各地的教师，以最先进的方式连接现场参与者 与50多个国家和地区的远程观众合作。详细的介绍主题已经 围绕与基础科学、转化、临床研究、常规临床方面相关的主题进行安排， 成像、血管内治疗和脑中侧枝的护理问题的系统。确认的方案 本次为期两天半的会议分为40分钟的会议，专门讨论翻译中的关键问题。 在地球仪中风治疗中的应用。特别重要的是， 将基于2018年开展的国家调查报告卒中的血流动力学。的 主持海报会议，神经血管器械研讨会和穿插网络 机会将加强这一新兴领域的合作举措。快速传播电子 海报、会议记录和其他出版物，同以往会议一样，将加强这一独特和 年度研讨会。已经为适当的代表性作出了专门努力 实现妇女人数均等，招聘代表性不足的少数民族和残疾人， 最终导致了参与者的极端多样化。为任职人数不足的少数群体提供受训人员奖励 将显著增强本次会议的教育影响。可衡量的结果将 量化这次研讨会对NINDS使命的影响，以提高对抵押品的认识， 中风导致的神经系统疾病的负担。这个独特的专业论坛从一个国家的延伸- 世界各地的艺术场馆都强调宣传品的及时影响，令人鼓舞， 最大化参与、快速扩散和网络资源增值。