8th International Symposium on Collaterals to the Brain

第八届脑络国际研讨会

• 批准号: 10318759
• 负责人: DAVID SIGMUND LIEBESKIND
• 金额: $ 1.25万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-15 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10318759
• 关键词: Achievement; Acute; Address; Adult; Area; Automobile Driving; Award; Basic Science; Blood flow; Brain; Cerebral Ischemia; Clinical; Clinical Research; Collaborations; Collateral Circulation; Communication; Communities; Complement; Country; Data Analyses; Decision Making; Development; Devices; Diffusion; Disabled Persons; Educational workshop; Ensure; Evaluation; Exhibits; Faculty; Goals; Hybrids; Image; Individual; International; Internet; Ischemia; Ischemic Stroke; Knowledge; Logistics; Measurable; Medical; Mentors; Methods; Mission; Modeling; National Institute of Neurological Disorders and Stroke; Nature; Outcome; Participant; Persons; Public Health; Publications; Publishing; Questionnaires; Recovery; Request for Proposals; Research; Research Personnel; Resources; Role; Science; Secure; Series; Site; Stroke; Stroke prevention; Structure; Surveys; Technology; Therapeutic; Time; TimeLine; Translating; Translational Research; Translations; Triage; Underrepresented Minority; United States National Institutes of Health; Vascular Cognitive Impairment; Woman; base; burden of illness; care systems; career; cerebral hemodynamics; clinical implementation; clinically relevant; data sharing; disability; education resources; ethnic minority population; experience; hemodynamics; improved; innovation; live stream; meetings; member; mobile computing; multidisciplinary; nervous system disorder; neurovascular; novel; outreach; pandemic disease; parity; posters; precision medicine; programs; racial and ethnic; recruit; stroke education; stroke therapy; success; symposium; technological innovation; treatment strategy; virtual; virtual platform; web site; webinar

PROJECT SUMMARY/ABSTRACT The 8th International Symposium on Collaterals to the Brain is a multidisciplinary scientific conference focused on collateral circulation in ischemic stroke. This proposal requests partial support for a conference with broad, long-term objectives that will advance current research on collateral blood flow and identify gaps in current treatment strategies around the world. The collaterome, or individual capacity to offset ischemia in the brain, and determination of a favorable collateral profile have become pivotal factors in the consideration of cerebral ischemia and the precision medicine of stroke driving individualized medical decision-making. The conference directly addresses the most pressing issues and gaps in optimally defining collateral status that limits the realization of stroke therapies around the world. Decisive challenges include generalizability of optimal triage and selection paradigms based on collateral status for definitive treatment of ischemic stroke, rapid dissemination of expert methods and transformative advances, and the urgent need to leverage networking opportunities for stroke education and science related to hemodynamics of collaterals to the brain. The aims of this conference will convene faculty from around the world to connect on-site participants at the state-of-the-art facility with remote audiences in more than 75 countries and regions. Detailed presentation topics have been arranged around themes relating to the basic science, translational, clinical research, routine clinical aspects, imaging, endovascular therapy, and systems of care issues of collaterals in the brain. The confirmed program of this 3-day conference is structured into 40-minute sessions devoted to key issues in translating the collaterome in stroke therapy across the globe. Of particular importance is the interval progress on the use of hemodynamics in stroke that will be presented based on the annual country-based surveys. The dedicated sessions for debates, solutions, and the early career and basic science moderated poster session, hands-on neurovascular device workshop and interspersed networking opportunities will enhance collaborative initiatives in this burgeoning field. Rapid dissemination of electronic posters, proceedings, and other publications, as in past meetings, will intensify the impact of this unique and esteemed annual Symposium. Dedicated efforts for appropriate representation have already been delineated to have parity in the numbers of women, recruit underrepresented minorities and persons with disabilities, culminating in an extremely diverse spectrum of participants. Trainee awards for underrepresented minorities from the local region will markedly enhance the educational impact of this meeting. Measurable outcomes will quantify the impact of this symposium on the NINDS mission to enhance knowledge of collaterals and reduce the burden of neurological disease due to stroke. This unique forum of expertise extending from a state-of-the-art venue across the world emphasizes the timely impact of collaterals on a monumental scale, encouraging maximal participation, rapid diffusion, and added value of networking resources.

项目摘要/摘要 第八届国际大脑抵押品研讨会是一个多学科科学会议，旨在涉及缺血性中风的副作用。该提案要求为一次会议提供部分支持，该会议具有广泛的长期目标，该会议将推动当前关于附带血流的研究，并确定全球当前治疗策略中的差距。考虑到脑缺血的副标或个人能力抵消大脑中缺血的能力以及确定有利的附带概况的确定已成为关键因素，并考虑了脑缺血和中风的精确药物，以推动个性化的医疗决策。会议直接解决了最紧迫的问题和差距，以最佳定义附带地位，从而限制了世界各地的中风疗法的实现。决定性的挑战包括最佳分类和选择范式的概括性，基于附带状态的选择范式，以确定治疗缺血性中风的确定性，专家方法的快速传播和变革性的进步，以及迫切需要利用与大脑血流动力学相关的中风教育和科学的网络机会。这次会议的目的将召集来自世界各地的教师，将最先进设施的现场参与者与75多个国家和地区的偏远受众联系起来。已经围绕与基础科学，翻译，临床研究，常规临床方面，成像，血管内治疗以及大脑侧支护理问题的系统有关的主题安排了详细的演示主题。这项为期三天的会议的确认计划构成了40分钟的会议，该课程致力于转化全球中风疗法中的二线蛋白酶的关键问题。特别重要的是，将根据年度基于国家的调查提出的血液动力学在中风中使用的间隔进展。辩论，解决方案以及早期职业和基础科学的专门会议主持海报会议，动手神经血管设备工作坊和散布的网络机会，将增强该领域中新兴领域的协作计划。像过去的会议一样，电子海报，会议记录和其他出版物的快速传播将加剧这一独特而受人尊敬的年度研讨会的影响。已经划定了为适当代表做出的专门努力，以使妇女人数均等，招募代表性不足的少数群体和残疾人，并以极为多样化的参与者为顶点。来自本地地区代表性不足的少数群体奖学金将显着增强这次会议的教育影响。可衡量的结果将量化该研讨会对NINDS使命的影响，以增强侧支知识并减轻中风引起的神经系统疾病的负担。这个独特的专业知识论坛从全世界的最先进的场所扩展到，强调了抵押品在巨大规模上的及时影响，鼓励最大程度地参与，快速扩散和网络资源的附加值。