RHYTHM: Restoring Health in You (and Your Partner) Through Movement

描述（由申请人提供）：促进癌症幸存者的健康和福祉是一项重要的公共卫生目标。相对较少的幸存者研究涉及妇科癌症幸存者。确定有效改善这一人群生活质量的生活方式干预措施仍有机会。此外，研究表明，癌症幸存者的配偶/伴侣的生活质量也会受到影响。相对未知的是如何设计和提供干预措施，以促进癌症幸存者及其配偶/伴侣的健康和福祉。在本研究中，我们有以下目的：(1)建立基于夫妻的舞蹈干预（RHYTHM）在妇科癌症幸存者及其配偶/伴侣中的可行性和可接受性；(2)量化对以下终点的潜在影响（和变化）：健康相关生活质量（HRQOL）、关系调整、身体活动和功能；(3)识别调解干预与结果之间关系的理论结构；(4)确定干预对参与者的成本。方法：我们将采用等候名单对照设计，从肿瘤诊所和阿拉巴马州癌症登记处招募50名妇科癌症幸存者及其配偶/伴侣。幸存者将完成他们的初级癌症治疗。干预组的参与者将接受由Fred Astaire舞蹈工作室提供的为期12周的舞蹈课程（以情侣为基础的舞蹈）。HRQOL（即SF36）、关系调整、体力活动与身体功能（即6分钟步行测试）、

DESCRIPTION (provided by applicant): Promoting the health and well-being of cancer survivors is an important public health goal. Relatively little survivorship research has engaged gynecological cancer survivors. Opportunities remain to identify lifestyle interventions efficacious in improving quality of life in this population. Moreover, research suggests that quality of life is also compromised in the spouses/partners of cancer survivors. Relatively unknown is how to design and deliver interventions that promote the health and well-being of both the cancer survivor and their spouse/partner. In the proposed study, we have the following Aims: (1) Establish the feasibility and acceptability of a couples-based dance intervention (RHYTHM) among gynecological cancer survivors and their spouses/partners; (2) Quantify potential effects (and variation) on the following endpoints: health-related quality of life (HRQOL), relationship adjustment, physical activity and functioning; (3) Identify theoretical constructs that mediate the relationship between the intervention and outcomes; and (4) Determine the cost of the intervention to participants. Methods: We will use a wait-list control design and enroll 50 gynecological cancer survivors and their spouses/partners recruited from oncology clinics and the Alabama State Cancer Registry. Survivors will have completed their primary cancer treatment. Participants in the intervention arm will receive dance lessons over a 12-week period (couples-based dance) provided by Fred Astaire Dance studios. HRQOL (i.e., SF36), relationship adjustment, physical activity and physical function (i.e., 6-minute walk test), will be assessed at baseline, immediately post-intervention, and 6 months post- intervention. Outcomes will be measured in both cancer survivors and their partners. Significance: Delivering quality cancer care across the cancer continuum is a national priority. Our partner-based dance intervention is a novel approach to enhancing quality of life, enhancing relationship outcomes, and promoting a healthy lifestyle in gynecologic cancer survivors and their partners. Results of this exploratory study will inform initiatives that seek to maintain the health and well-being of cancer survivors and those they love. Public Health Impact: Consistent with the Institute of Medicine's goal to deliver cancer care that promotes a healthy lifestyle and improves quality of life of cancer survivors, our novel study will explore the potential of an intervention (couple-based dance) on improving these outcomes for both cancer survivors and their partners. In this unique approach, we test the efficacy of an intervention already available in many communities. If dance interventions are deemed efficacious, the potential for broad based dissemination of similar programs is great. PUBLIC HEALTH RELEVANCE: Maintaining the health and well-being of cancer survivors is an important public health goal. In this innovative study, we will engage gynecological cancer survivors and their spouses/partners in a couple-based dance intervention. We will establish the feasibility and acceptability of delivering this intervention and assess its impact on quality of lfe, physical activity and function, and relationship adjustment in both cancer survivors and their spouses/partners.