Mayo Clinic Center for Translational Science Activities

梅奥诊所CTSA的总体目标是继续为 梅奥诊所的临床和转化科学(CTS)，最终将改善人类健康。在这 在此背景下，我们寻求使Mayo CTSA及其利用的资源成为效率的引擎 临床和转化性研究，同时也是创新的驱动力。我们还寻求将我们的 与财团范围内旨在协调和调整的当地活动。为了实现我们的目标，我们 这次更新有六个最重要的具体目标：目标1-培训和保持卓越的 多学科临床和转化科学工作人员。这支队伍包括这两个团队 调查人员和支持人员。目标2--消除翻译工作中的障碍。这将是 通过a)继续努力精简监管和合规，b)提供 为调查人员提供出色的设计、生物统计和伦理支持，以及c)进一步整合支持 服务。目标3-与提供者和社区合作，改善医疗保健提供和 社区卫生。这包括对基于实践的研究、社区参与的实质性承诺 研究并将比较有效性研究转化为临床实践。目标4-部署 先进的设施等核心资源，增加临床研究的价值。有价值的 在本文中定义为质量和成本的商，目标是提高质量，降低成本，并 为全面的临床和转化性研究提供资源。目标5--刺激小说 通过有针对性地支持创新的试点和可行性研究以及 促进新方法的发展。目标6-利用信息学整合和促进 临床和翻译研究。这包括信息学的广泛视角，包括：a) 为CTS开发标准化的电子数据捕获和分析工具，b)强有力的协商和 医疗信息学工具，利用梅奥对电子临床系统的承诺，以及c) 生物信息学服务和能力，将有助于促进“新生物学”在临床上的应用 和翻译调查。这一愿景与梅奥诊所所宣称的使命完全一致： 通过综合的临床实践、教育和 研究。“

The overall goal of the Mayo Clinic CTSA is to continue to build a broad-based and integrated home for clinical and translational science (CTS) at Mayo Clinic that will ultimately improve human health. In this context, we seek to make the Mayo CTSA and the resources it leverages both an engine of efficiency for clinical and translational research and at the same time a driver of innovation. We also seek to integrate our local activities with consortium wide efforts directed at coordination and alignment. To achieve our goal we have six overarching specific aims for this renewal: Aim 1 - Train and maintain an outstanding multidisciplinary clinical and translational sciences workforce. This workforce includes teams of both investigators and support staff. Aim 2 - Eliminate barriers to the work of translation. This will be accomplished through a) continued efforts at regulatory and compliance streamlining, b) provision of outstanding design, biostatistics, and ethics support for investigators, and c) further integration of support services. Aim 3 - Collaborate with providers and communities to improve health care delivery and community health. This includes substantial commitments to practice-based research, communityengaged research and translating comparative effectiveness research into clinical practice. Aim 4 - Deploy advanced facilities and other core resources to increase the value of clinical research. With value defined in this context as the quotient of quality and cost, the goal is to increase quality, decrease costs, and provide resources to the full spectrum of clinical and translational investigation. Aim 5 - Stimulate novel research directions and methodologies by targeted support of innovative pilot and feasibility studies and fostering the development of novel methodologies. Aim 6 - Employ informatics to integrate and facilitate clinical and translational investigation. This encompasses a broad view of informatics including: a) developing a standardized electronic data capture and analysis tools for CTS, b) robust consultation and tools for medical informatics that leverage Mayo's commitments to electronic clinical systems, and c) bioinformatics services and capabilities that will help facilitate the application of the "new biology" to clinical and translational investigation. This vision is entirely consistent with the stated mission of Mayo Clinic: "To provide the best care to every patient every day through integrated clinical practice, education, and research."