Gene Therapy for Canine X-linked SCID

犬 X 连锁 SCID 的基因治疗

• 批准号: 8259611
• 负责人: Peter J Felsburg
• 金额: $ 62.61万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-15 至 2013-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8259611
• 关键词: 11 year old; 2 year old; Accounting; Adverse effects; Aftercare; Animal Disease Models; Animal Model; B-Lymphocytes; Blood; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; CD34 gene; Canis familiaris; Cell Count; Cells; Characteristics; Clinical; Clinical Trials; Development; Disease; Engraftment; Evaluation; Gene Transfer; Genetic; Goals; Hematological Disease; Hematopoiesis; Hematopoietic; Homing; Human; Immune; Immune System Diseases; Immunologic Deficiency Syndromes; Infusion procedures; Interleukin 2 Receptor; Intravenous; Kinetics; Length; Lentivirus Vector; Life; Link; Modeling; Monitor; Mutation; Myelogenous; Neonatal; Pathway interactions; Patients; Principal Investigator; Production; Property; Research Design; Research Methodology; Retroviral Vector; Safety; Site; Stem cells; Stromal Cells; System; T-Cell Leukemia; T-Lymphocyte; Testing; Time; Tissues; X-Linked Severe Combined Immunodeficiency; boys; cytokine; gene correction; gene therapy; gene therapy clinical trial; human disease; improved; in vivo; novel; pre-clinical; preclinical study; pressure; progenitor; programs; reconstitution; self-renewal; therapeutic transgene; vector

Program Director/Principal Investigator (Last, First, Middle): Felsburg, Peter J. 2R01 AI043745-11A2

项目主任/首席调查员(最后、第一、中间)：费尔斯堡，Peter J.2R01 AI043745-11A2