权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Lab. Animal

实验室。

基本信息

批准号：
8296645
负责人：
Sandra Sexton
金额：
$ 38.41万
依托单位：
ROSWELL PARK CANCER INSTITUTE CORP
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/8296645
关键词：
Accreditation Adopted Air American Animal Care and Use Committees Animal Experimentation Animal Husbandry Animal Technicians Animals Antineoplastic Agents Ascites Backcrossings Beds Budgets Cancer Center Support Grant Canis familiaris Carcinogens Caring Certification Collection Complex Cost Control Crossbreeding Decontamination Development Diagnostic Ensure Environment Equipment and supply inventories Faculty Food Funding Grant Health Health Services Research Horizontal Disease Transmission Human Resources Hybridomas Image Immune Inbreeding Incineration Institutes International Knockout Mice Laboratories Laboratory Animal Medicine Laboratory Animal Science Laboratory Animals Licensing Livestock Maintenance Medical Medical Research Modeling Mus New York Peer Review Procedures Process Production Protocols documentation Rattus Registries Research Personnel Residencies Resources Rodent Roswell Park Cancer Institute Safety Services Sterility Stream Techniques Technology Training Training Programs Transgenic Mice Transgenic Organisms Veterinarians Water Woodchuck Work animal care animal resource cancer cell cost effective high standard human disease irradiation knockout gene laboratory facility meetings member monoclonal antibody production mouse model mutant pathogen polyclonal antibody prevent programs square foot standard of care tool tumor wasting

项目摘要

The Laboratory Animal Resource is responsible for promoting the humane care of laboratory animals used by CCSG investigators. In June 2005, the Association for the Assessment and Accreditation of Laboratory Animal Care International (AAALAC International) reviewed and re-accredited the Resource for a full three years. The Resource provides specialized animal husbandry; veterinary medical care; animal health surveillance; diagnostic laboratory facilities; irradiation services, research technical services, and faculty training to support more than 150 Institute Animal Care and Use Committee (IACUC) -approved animal use protocols. Additional services include immune-deficient rodent production, imaging facilities, import and export of animals, and hybridoma ascites production and collection in mice. Daily animal inventories of 24,000 to 28,000 include primarily rodents, but also include woodchucks, dogs and occasionally farm animals. The Resource Director is a New York State licensed veterinarian who completed a residency-training program in Laboratory Animal Medicine. Eighteen members of the technical staff are certified through the Certification and Registry Board of the American Association for Laboratory Animal Science (AALAS). The Laboratory Animal Resource is located in the four-story 39,000 net square feet (nsf) Vivarium, which opened in 1998, is adjacent to the Medical Research Complex (MRC). An additional 8,000 nsf of newly renovated space is available in the Cancer Cell Center. Laboratories for work with gene knockout and transgenic technologies in mice are immediately adjacent to animal holding rooms. Continued support through the CCSG will permit the Resource to provide a standard of care and use that meets or exceeds applicable state and federal standards, maintain full AAALAC International accreditation, and furnish investigators with a comprehensive program for safe, appropriate and cost effective research animal use. The Laboratory Animal Resource serves investigators from all six CCSG programs and offers continuing training opportunities to enhance animal safety and resource usage. The Resource remains an important tool for recruitment and retention of peer-reviewed investigators due to high efficiency, dedicated well-trained staff and low chargebacks to investigators made possibly by RPCI subsidy. Over the last grant period, CCSG Developmental funds were allocated to expand a new and unique service titled, Mouse Tumor Model Resource (MTMR). The MTMR provides services for specialized techniques, as well as mouse models of human disease. The Resource is used by all six CCSG Programs and 93% of users are CCSG members. $168,487 in CSCG support is requested, representing 6% of the total operating budget.

实验动物资源部负责促进实验动物的人道关怀 CCSG调查人员使用的。2005年6月，评估和认证协会实验动物护理国际组织（AAALAC International）审查并重新认证了整整三年。资源提供专业畜牧业;兽医医疗保健;动物卫生监督;诊断实验室设施;辐照服务，研究技术服务，以及教师培训，以支持150多个研究所动物护理和使用委员会（IACUC）批准动物使用方案。其他服务包括免疫缺陷啮齿动物生产，成像设施，动物进出口、小鼠杂交瘤腹水生产和收集。每日动物 24，000至28，000的库存主要包括啮齿动物，但也包括土拨鼠，狗和偶尔也有农场动物。资源总监是一名纽约州执业兽医，完成了住院培训实验动物医学实验室18名技术人员通过了美国实验动物科学协会（AALAS）认证和注册委员会。的实验室动物资源位于四层楼高的39,000平方英尺（nsf）的动物园， 1998年，毗邻医学研究综合体（MRC）。新增8，000 nsf新装修癌症细胞中心有空位。基因敲除和转基因实验室在小鼠中使用的技术紧邻动物饲养室。继续支持通过 CCSG将允许资源提供符合或超过适用状态的护理和使用标准和联邦标准，保持完整的AAALAC国际认证，并为研究者提供安全、适当和具有成本效益的研究动物使用的综合计划。实验室动物资源为所有六个CCSG项目的研究者提供服务，提供持续培训机会，以提高动物安全和资源利用。资源仍然是这是征聘和留住经过同行审查的调查员的重要工具，因为它效率高，训练有素的工作人员和低收费的研究人员可能由RPCI补贴。在上一个赠款期间，CCSG发展基金被分配用于扩大一个新的和独特的小鼠肿瘤模型资源（Mouse Tumor Model Resource，MTMR）MTMR为专业人员提供服务技术，以及人类疾病的小鼠模型。该资源被CCSG所有六个计划使用，93%的用户是CCSG成员。$168，487 在CSCG的支持，要求占总运营预算的6%。