权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Lab. Animal

实验室。

基本信息

批准号：
8296645
负责人：
Sandra Sexton
金额：
$ 38.41万
依托单位：
ROSWELL PARK CANCER INSTITUTE CORP
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/8296645
关键词：
Accreditation Adopted Air American Animal Care and Use Committees Animal Experimentation Animal Husbandry Animal Technicians Animals Antineoplastic Agents Ascites Backcrossings Beds Budgets Cancer Center Support Grant Canis familiaris Carcinogens Caring Certification Collection Complex Cost Control Crossbreeding Decontamination Development Diagnostic Ensure Environment Equipment and supply inventories Faculty Food Funding Grant Health Health Services Research Horizontal Disease Transmission Human Resources Hybridomas Image Immune Inbreeding Incineration Institutes International Knockout Mice Laboratories Laboratory Animal Medicine Laboratory Animal Science Laboratory Animals Licensing Livestock Maintenance Medical Medical Research Modeling Mus New York Peer Review Procedures Process Production Protocols documentation Rattus Registries Research Personnel Residencies Resources Rodent Roswell Park Cancer Institute Safety Services Sterility Stream Techniques Technology Training Training Programs Transgenic Mice Transgenic Organisms Veterinarians Water Woodchuck Work animal care animal resource cancer cell cost effective high standard human disease irradiation knockout gene laboratory facility meetings member monoclonal antibody production mouse model mutant pathogen polyclonal antibody prevent programs square foot standard of care tool tumor wasting

项目摘要

The Laboratory Animal Resource is responsible for promoting the humane care of laboratory animals used by CCSG investigators. In June 2005, the Association for the Assessment and Accreditation of Laboratory Animal Care International (AAALAC International) reviewed and re-accredited the Resource for a full three years. The Resource provides specialized animal husbandry; veterinary medical care; animal health surveillance; diagnostic laboratory facilities; irradiation services, research technical services, and faculty training to support more than 150 Institute Animal Care and Use Committee (IACUC) -approved animal use protocols. Additional services include immune-deficient rodent production, imaging facilities, import and export of animals, and hybridoma ascites production and collection in mice. Daily animal inventories of 24,000 to 28,000 include primarily rodents, but also include woodchucks, dogs and occasionally farm animals. The Resource Director is a New York State licensed veterinarian who completed a residency-training program in Laboratory Animal Medicine. Eighteen members of the technical staff are certified through the Certification and Registry Board of the American Association for Laboratory Animal Science (AALAS). The Laboratory Animal Resource is located in the four-story 39,000 net square feet (nsf) Vivarium, which opened in 1998, is adjacent to the Medical Research Complex (MRC). An additional 8,000 nsf of newly renovated space is available in the Cancer Cell Center. Laboratories for work with gene knockout and transgenic technologies in mice are immediately adjacent to animal holding rooms. Continued support through the CCSG will permit the Resource to provide a standard of care and use that meets or exceeds applicable state and federal standards, maintain full AAALAC International accreditation, and furnish investigators with a comprehensive program for safe, appropriate and cost effective research animal use. The Laboratory Animal Resource serves investigators from all six CCSG programs and offers continuing training opportunities to enhance animal safety and resource usage. The Resource remains an important tool for recruitment and retention of peer-reviewed investigators due to high efficiency, dedicated well-trained staff and low chargebacks to investigators made possibly by RPCI subsidy. Over the last grant period, CCSG Developmental funds were allocated to expand a new and unique service titled, Mouse Tumor Model Resource (MTMR). The MTMR provides services for specialized techniques, as well as mouse models of human disease. The Resource is used by all six CCSG Programs and 93% of users are CCSG members. $168,487 in CSCG support is requested, representing 6% of the total operating budget.

实验动物资源负责促进实验动物的人文关怀由CCSG调查人员使用。2005年6月，评估和认可协会国际实验动物保护协会(AAALAC International)对资源进行了审查和重新认证整整三年。该资源提供专门的畜牧业；兽医医疗；动物健康监测；诊断实验室设施；辐射服务、研究技术服务和支持150多个研究所动物保护和使用委员会(IACUC)的教师培训-批准动物使用协议。其他服务包括免疫缺陷啮齿动物的生产、成像设施、动物进出口，杂交瘤小鼠腹水的生产和采集。日常生活动物 2.4万至2.8万的物种主要包括啮齿动物，但也包括土拨鼠、狗和偶尔会有农场的动物。资源总监是一名纽约州注册兽医，完成了住院医师培训实验动物医学专业。18名技术人员通过美国实验动物科学协会(AALAS)认证和注册委员会。这个实验室动物资源位于四层楼高的3.9万平方英尺(NSF)的隔间内，开放 1998年，毗邻医学研究综合体(MRC)。新翻修的额外8,000 NSF 癌症细胞中心有空位。用于基因敲除和转基因工作的实验室老鼠身上的技术紧邻动物拘留室。通过以下方式继续提供支持 CCSG将允许资源提供符合或超过适用州的护理和使用标准和联邦标准，保持完全的AAALAC国际认证，并为调查人员提供安全、适当和经济高效的研究动物使用的综合计划。实验动物资源为来自CCSG所有六个项目的研究人员提供服务持续培训机会，以加强动物安全和资源利用。该资源仍然是招聘和留住同行评议的调查员的重要工具，因为效率高、专职训练有素的员工和对调查人员的低按存储容量使用计费可能是由RPCI补贴造成的。在上一个授权期内，CCSG开发基金被分配用于扩展一个新的和独特的服务名为，小鼠肿瘤模型资源(MTMR)。MTMR为专业人士提供服务技术，以及人类疾病的老鼠模型。该资源被所有六个CCSG计划使用，93%的用户是CCSG成员。168,487美元在CSCG中，请求提供支助，占业务预算总额的6%。