Lab. Animal
实验室。
基本信息
- 批准号:8296645
- 负责人:
- 金额:$ 38.41万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:
- 资助国家:美国
- 起止时间:至
- 项目状态:未结题
- 来源:
- 关键词:AccreditationAdoptedAirAmericanAnimal Care and Use CommitteesAnimal ExperimentationAnimal HusbandryAnimal TechniciansAnimalsAntineoplastic AgentsAscitesBackcrossingsBedsBudgetsCancer Center Support GrantCanis familiarisCarcinogensCaringCertificationCollectionComplexCost ControlCrossbreedingDecontaminationDevelopmentDiagnosticEnsureEnvironmentEquipment and supply inventoriesFacultyFoodFundingGrantHealthHealth Services ResearchHorizontal Disease TransmissionHuman ResourcesHybridomasImageImmuneInbreedingIncinerationInstitutesInternationalKnockout MiceLaboratoriesLaboratory Animal MedicineLaboratory Animal ScienceLaboratory AnimalsLicensingLivestockMaintenanceMedicalMedical ResearchModelingMusNew YorkPeer ReviewProceduresProcessProductionProtocols documentationRattusRegistriesResearch PersonnelResidenciesResourcesRodentRoswell Park Cancer InstituteSafetyServicesSterilityStreamTechniquesTechnologyTrainingTraining ProgramsTransgenic MiceTransgenic OrganismsVeterinariansWaterWoodchuckWorkanimal careanimal resourcecancer cellcost effectivehigh standardhuman diseaseirradiationknockout genelaboratory facilitymeetingsmembermonoclonal antibody productionmouse modelmutantpathogenpolyclonal antibodypreventprogramssquare footstandard of caretooltumorwasting
项目摘要
The Laboratory Animal Resource is responsible for promoting the humane care of laboratory animals
used by CCSG investigators. In June 2005, the Association for the Assessment and Accreditation of
Laboratory Animal Care International (AAALAC International) reviewed and re-accredited the Resource for a
full three years. The Resource provides specialized animal husbandry; veterinary medical care; animal
health surveillance; diagnostic laboratory facilities; irradiation services, research technical services, and
faculty training to support more than 150 Institute Animal Care and Use Committee (IACUC) -approved
animal use protocols. Additional services include immune-deficient rodent production, imaging facilities,
import and export of animals, and hybridoma ascites production and collection in mice. Daily animal
inventories of 24,000 to 28,000 include primarily rodents, but also include woodchucks, dogs and
occasionally farm animals.
The Resource Director is a New York State licensed veterinarian who completed a residency-training
program in Laboratory Animal Medicine. Eighteen members of the technical staff are certified through the
Certification and Registry Board of the American Association for Laboratory Animal Science (AALAS). The
Laboratory Animal Resource is located in the four-story 39,000 net square feet (nsf) Vivarium, which opened
in 1998, is adjacent to the Medical Research Complex (MRC). An additional 8,000 nsf of newly renovated
space is available in the Cancer Cell Center. Laboratories for work with gene knockout and transgenic
technologies in mice are immediately adjacent to animal holding rooms. Continued support through the
CCSG will permit the Resource to provide a standard of care and use that meets or exceeds applicable state
and federal standards, maintain full AAALAC International accreditation, and furnish investigators with a
comprehensive program for safe, appropriate and cost effective research animal use.
The Laboratory Animal Resource serves investigators from all six CCSG programs and offers
continuing training opportunities to enhance animal safety and resource usage. The Resource remains an
important tool for recruitment and retention of peer-reviewed investigators due to high efficiency, dedicated
well-trained staff and low chargebacks to investigators made possibly by RPCI subsidy.
Over the last grant period, CCSG Developmental funds were allocated to expand a new and unique
service titled, Mouse Tumor Model Resource (MTMR). The MTMR provides services for specialized
techniques, as well as mouse models of human disease.
The Resource is used by all six CCSG Programs and 93% of users are CCSG members. $168,487
in CSCG support is requested, representing 6% of the total operating budget.
实验动物资源负责促进实验动物的人文关怀
由CCSG调查人员使用。2005年6月,评估和认可协会
国际实验动物保护协会(AAALAC International)对资源进行了审查和重新认证
整整三年。该资源提供专门的畜牧业;兽医医疗;动物
健康监测;诊断实验室设施;辐射服务、研究技术服务和
支持150多个研究所动物保护和使用委员会(IACUC)的教师培训-批准
动物使用协议。其他服务包括免疫缺陷啮齿动物的生产、成像设施、
动物进出口,杂交瘤小鼠腹水的生产和采集。日常生活动物
2.4万至2.8万的物种主要包括啮齿动物,但也包括土拨鼠、狗和
偶尔会有农场的动物。
资源总监是一名纽约州注册兽医,完成了住院医师培训
实验动物医学专业。18名技术人员通过
美国实验动物科学协会(AALAS)认证和注册委员会。这个
实验室动物资源位于四层楼高的3.9万平方英尺(NSF)的隔间内,开放
1998年,毗邻医学研究综合体(MRC)。新翻修的额外8,000 NSF
癌症细胞中心有空位。用于基因敲除和转基因工作的实验室
老鼠身上的技术紧邻动物拘留室。通过以下方式继续提供支持
CCSG将允许资源提供符合或超过适用州的护理和使用标准
和联邦标准,保持完全的AAALAC国际认证,并为调查人员提供
安全、适当和经济高效的研究动物使用的综合计划。
实验动物资源为来自CCSG所有六个项目的研究人员提供服务
持续培训机会,以加强动物安全和资源利用。该资源仍然是
招聘和留住同行评议的调查员的重要工具,因为效率高、专职
训练有素的员工和对调查人员的低按存储容量使用计费可能是由RPCI补贴造成的。
在上一个授权期内,CCSG开发基金被分配用于扩展一个新的和独特的
服务名为,小鼠肿瘤模型资源(MTMR)。MTMR为专业人士提供服务
技术,以及人类疾病的老鼠模型。
该资源被所有六个CCSG计划使用,93%的用户是CCSG成员。168,487美元
在CSCG中,请求提供支助,占业务预算总额的6%。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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