Neuromuscular control of the human tongue
人类舌头的神经肌肉控制
基本信息
- 批准号:8315988
- 负责人:
- 金额:$ 35.99万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-09-25 至 2014-08-31
- 项目状态:已结题
- 来源:
- 关键词:Action PotentialsAxonBehaviorBreathingComplexDataDeglutitionDevelopmentDiagnosisElementsExhibitsGoalsHumanInterventionInvestigationLarynxLibrariesMasticationMotorMotor CortexMotor NeuronsMovementMuscleMuscle FibersMuscle functionNervous system structureNeuraxisOralOrganOutputPatternPhonationProcessProductionPropertyRelative (related person)RespirationRespiratory MusclesRestSkeletal MuscleSleepSpeechSpeech DisordersSynapsesSystemTechniquesTestingTherapeuticTimeTongueWorkbasebonecentral pattern generatordesignhuman subjectinsightlung volumeminimally invasiveneuromuscularneuroregulationpresynapticrelating to nervous systemresearch studyrespiratorytongue root
项目摘要
The tongue is a complex muscular organ that is critical for oro-motor behaviors such as swallowing,
breathing, speaking and chewing. The astonishing complexity and precision of the voluntary
movements performed by the tongue depend upon the coordination of intrinsic (origin and insertion
within the body of the tongue) and extrinsic (attached to bone and inserted into the base of tongue)
tongue muscles. Until recently, almost all studies of lingual muscle function whether in speech,
respiration or deglutition have concerned themselves with the study of whole muscle electromyographic
(EMG) activities. Recently, we characterized respiratory-related tongue muscle and motor unit
activities in healthy human subjects as a function of sleep/wake and in slow volitional movements. The
results of this work provided de novo insights into lingual motor function and a platform from which to
begin studies aimed at identifying how tongue muscles are controlled in more complex volitional
behaviors. The current application builds thematically on previous work by the PI and yet departs from
previous investigations in incorporating critical elements of the speech production process. Specifically,
we propose to examine tongue muscle and motor unit activities and the potential for these activities to
be modulated by inputs arising in the respiratory, phonatory (laryngeal) and/or supralaryngeal (oral-
articulatory) subsystems. Understanding muscle and MU activities as a function of these influences
separately and when successively overlaid is a logical first-step toward understanding how tongue
muscle and motor unit activities are modulated in the more complex volitional behavior that is human
speech production.
舌头是一个复杂的肌肉器官,对吞咽等口腔运动行为至关重要,
呼吸说话咀嚼志愿者的惊人的复杂性和精确性
舌头的运动取决于内在的协调(起源和插入
舌内)和外(附着于骨并插入舌根)
舌头肌肉直到最近,几乎所有关于舌肌功能的研究,
呼吸或吞咽都涉及到整个肌肉肌电图的研究
(EMG)活动最近,我们的特点与舌相关的肌肉和运动单位
活动在健康的人类受试者作为睡眠/觉醒和缓慢的意志运动的函数。的
这项工作的结果提供了对语言运动功能的重新认识,并提供了一个平台,
开始研究旨在确定舌头肌肉是如何控制在更复杂的意志
行为。目前的应用程序建立在PI以前的工作的主题上,
以前的研究纳入语音生产过程的关键要素。具体地说,
我们建议检查舌肌和运动单位的活动,以及这些活动的潜力,
通过呼吸、发声(喉)和/或喉上(口)中产生的输入来调节,
发音)子系统。了解肌肉和MU活动作为这些影响的函数
单独和连续重叠时,是理解语言如何
肌肉和运动单位的活动在人类更复杂的意志行为中受到调节
言语产生
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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E. FIONA BAILEY其他文献
E. FIONA BAILEY的其他文献
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{{ truncateString('E. FIONA BAILEY', 18)}}的其他基金
Time-efficient inspiratory muscle strength training for improving blood pressure and vascular function in older adults with sleep-disordered breathing
省时的吸气肌力量训练可改善患有睡眠呼吸障碍的老年人的血压和血管功能
- 批准号:
10045685 - 财政年份:2020
- 资助金额:
$ 35.99万 - 项目类别:
Time-efficient inspiratory muscle strength training for improving blood pressure and vascular function in older adults with sleep-disordered breathing
省时的吸气肌力量训练可改善患有睡眠呼吸障碍的老年人的血压和血管功能
- 批准号:
10264827 - 财政年份:2020
- 资助金额:
$ 35.99万 - 项目类别:
Time-efficient inspiratory muscle strength training for improving blood pressure and vascular function in older adults with sleep-disordered breathing
省时的吸气肌力量训练可改善患有睡眠呼吸障碍的老年人的血压和血管功能
- 批准号:
10413239 - 财政年份:2020
- 资助金额:
$ 35.99万 - 项目类别:
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