Basal forebrain and cognitive aging: Novel experimental and theraptutic avenues

基底前脑和认知衰老：新的实验和治疗途径

• 批准号: 8180233
• 负责人: JENNIFER Lynn BIZON
• 金额: $ 27.26万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8180233
• 关键词: Acetylcholine; Ache; Adopted; Affect; Age; Age-associated memory impairment; Aging; Aging-Related Process; Alzheimer' s Disease; Attenuated; Biochemical; Butyric Acids; Cessation of life; Cholinergic Receptors; Clinical; Clinical Treatment; Cognition; Cognitive; Cognitive aging; Cognitive deficits; Confocal Microscopy; Data; Diagnosis; Discrimination; Discrimination Learning; Disease; Early Diagnosis; Elderly; Exhibits; Experimental Designs; Figs - dietary; Functional disorder; GABA Agents; GABA-B Receptor; Hippocampus (Brain); Homeostasis; Human; Impaired cognition; Impairment; Individual; Individual Differences; Investigation; Laboratories; Learning; Longevity; Measures; Medial; Memory; Memory Loss; Modeling; Morphology; Muscarinic Acetylcholine Receptor; Muscarinics; Neurobiology; Neuronal Dysfunction; Neurons; Odors; Pathway interactions; Performance; Pharmaceutical Preparations; Phenotype; Population; Preparation; Process; Property; Proteins; Quality of life; Rattus; Receptor Signaling; Regimen; Reporting; Reproducibility; Research; Research Personnel; Rodent; Rodent Model; Short-Term Memory; Signal Transduction; Slice; Staging; Structure; Synapses; Synaptic Transmission; System; Techniques; Temporal Lobe; Testing; Time; Training; United States; age related; aged; basal forebrain; cholinergic; cholinergic neuron; cognitive function; cohort; effective therapy; efficacy testing; expectation; gamma-Aminobutyric Acid; improved; inhibitor/antagonist; interest; male; middle age; mild neurocognitive impairment; neural circuit; novel; programs; receptor; receptor expression; transmission process; young adult