Training in Mechanisms and Clinical Presentation of Pain

描述（由申请人提供）：这个拟议的培训计划的总体目标是整合当前匹兹堡大学疼痛研究中丰富的培训环境的跨学科和转化方面。除了让受训者了解疼痛机制和疼痛表现的基本原理外，我们还将建立新的项目元素（临床经验、多实验室项目、课程），这些通常是单个研究者很难支持的。我们致力于采用综合方法来研究疼痛，因为该领域的重大突破只能通过多学科方法来实现，因此将纳入并促进[1]实验室（横向整合）和[2]研究人员和临床医生（纵向整合）之间的互动。因此，横向和纵向整合将是该培训计划的重要组成部分，该培训计划将包括三个核心要素：1)研究-不仅鼓励，而且期望多学科研究项目，以及接触疼痛/疼痛相关问题的临床管理。这些整合将通过组建多学科指导委员会来实现，该委员会将在四人委员会中至少包括一名临床教员。2)理论-学员将参加四门必修的学分课程：疼痛的机制和临床表现，疼痛杂志俱乐部，双周的当前疼痛研究报告，一门新课程疼痛模型-基本原理，测试和解释，以及每月的疼痛研讨会系列，学员将与著名的疼痛研究人员互动。3)实践-学员将通过第二门新课程-疼痛视角-接触到慢性疼痛患者的评估，诊断和治疗，这将为学员提供机会跟随疼痛医生，因为他们在匹兹堡大学医学中心的疼痛医学项目中面试，诊断和管理慢性疼痛患者。

DESCRIPTION (provided by applicant): The overarching goal of this proposed training program is to integrate interdisciplinary and translational aspects of the current, rich training environment in pain research at the University of Pittsburgh. In addition to exposure of trainees to fundamental principles of pain mechanisms and pain presentation, we will establish new program elements (clinical experiences, multi-laboratory projects, courses) that are typically very difficult for individual investigators to support. We are committed to an integrated approach to the study of pain because major breakthroughs in this field can only be achieved through multidisciplinary approaches, and thus will incorporate and facilitate interactions between [1] laboratories (horizontal integration) and [2] researchers and clinicians (vertical integration). Accordingly, horizontal and vertical integration will be essential components of this training program, which will consist of three core elements: 1) Research - Multidisciplinary research projects will not only be encouraged, but expected, as will exposure to clinical management of pain/pain-related problems. These integrations will be achieved through formation of multidisciplinary mentoring committees which will include at least one clinical faculty member among a four-member committee. 2) Theory - Trainees will participate in four required for-credit courses: Mechanisms and Clinical Presentation of Pain, Pain Journal Club, bi-weekly Current Research on Pain presentations, a new course Pain Models - Rationale, Testing and Interpretation as well as the monthly Pain Seminar Series, where trainees interact with prominent pain researchers. 3) Practice - Trainees will be exposed to the assessment, diagnosis and treatment of chronic pain patients through a 2nd new course - Pain Perspectives - that will provide trainees the opportunity to shadow pain physicians as they interview, diagnose and manage chronic pain patients within the Pain Medicine Program at the University of Pittsburgh Medical Center. PUBLIC HEALTH RELEVANCE: Pain is the principal reason for seeking medical attention. It respects no boundaries, is not restricted to any one disease or medical discipline, is distributed across the life span and experienced by all irrespective of status (economic, educational, etc.) or gender. Many tissue insults lead to chronic pain states which are poorly managed because the mechanisms underlying pain are incompletely understood. Thus, there is a compelling need to enhance and broaden the training of the next generation of pain researchers.