Administrative Module

行政安排 首席调查员：琳达·M·赞威尔。博士 Linda Zangwill博士拥有担任加州大学圣地亚哥分校NEI愿景研究核心的PI所需的领导和管理技能及经验。作为临床研究联席主任和影像数据评估与分析(IDEA)阅读中心主任，她一直负责汉密尔顿青光眼中心临床研究企业的发展和扩张。自1995年以来，Zangwill博士一直在为青光眼诊断创新研究(DIGS)的结构评估提供ROI资金，这导致我们在以下方面的能力得到显著提高：1)检测青光眼结构损伤和变化，2)了解视盘损伤和视野丧失之间的复杂关系，3)测量结构变化的速度，4)预测谁将出现进行性视野丧失。此外，作为NEI资助的非洲人下降和青光眼评估研究(ADAGE)、OHTS和EGPS：使用共焦扫描激光眼底镜检测青光眼以及OHTS的CSLO辅助研究的联合研究员，Zangwill博士拥有成熟的领导和管理技能，协调大型国内和国际多中心研究，与合作研究人员设定优先事项，并在保持极具成效的合作研究计划的同时满足最后期限。此外，她还负责开发一个集成的数据管理系统，提供(在安全的共享服务器上)阅读中心审查从挖掘和谚语中获得的结构、功能、临床和人口统计数据，供合作研究人员分析。这个数据管理系统需要她的计算机组(3个全时工作人员)、阅读中心工作人员(4个全职工作人员)和临床研究人员(4个工作人员)以及(加州大学圣地亚哥分校和其他地方的)临床研究人员和统计学家之间的协调。作为加州大学圣地亚哥分校愿景研究核心的PI，她将利用她的管理专业知识与模块主任和咨询委员会合作，实施透明的决策过程，建立具有明确时间表的现实预期，并确保及时回应调查人员和工作人员的关切。

ADMINISTRATIVE ARRANGEMENTS Principal Investigator: Linda M. Zangwill. PhD Dr. Linda Zangwill has the necessary leadership and management skills and experience to serve as PI of the UCSD NEI Vision Research Core. As Co-Director of Clinical Research, and as Director of the Imaging Data Evaluation and Analysis (IDEA) Reading Center, she has been responsible for development and expansion of the clinical research enterprise at the Hamilton Glaucoma Center. Dr. Zangwill has had continuous ROI funding since 1995 for the Diagnostic Innovations in Glaucoma Study (DIGS): Structural Assessment, which has led to significant improvements in our ability to 1) detect glaucomatous structural damage and change, 2) understand the complex relationship between optic disc damage and visual field loss, 3) measure the rate of structural change, 4) predict who will develop progressive visual field loss. In addition, as PI for the NEI funded African Descent and Glaucoma Evaluation Study (ADAGES), OHTS and EGPS: Glaucoma detection using Confocal Scanning Laser Ophthalmoscopy and co-Investigator for the CSLO Ancillary Study to the OHTS, Dr. Zangwill has proven leadership and management skills coordinating large national and international multi-center studies, working with collaborating investigators to set priorities, and meet deadlines while maintaining an extremely productive collaborative research program. Moreover, she has been responsible for the development of an integrated data management system that provides (on a secure shared server), reading center reviewed structural, functional, clinical and demographic data acquired from the DIGS and ADAGES to collaborating researchers for analysis. This data management system required the coordination between her computer group (3 FTEs), Reading Center staff (4 FTEs) and clinical research staff (4 staff) as well as collaborating clinical researchers (at UCSD and elsewhere) and statisticians. As PI for the UCSD Vision Research Core she will bring her management expertise to work with module directors and the Advisory committee to implement a transparent decision-making process, to establish realistic expectations with clear timelines and to ensure timely response to investigator and staff concerns.