NEI Center Core Grant for Vision Research

总结 整体 视觉研究核心补助金的总体目的是提供核心服务和资源， 提高和加速视觉研究社区的生产力和影响力在大学 加州，圣地亚哥。具体来说，视觉研究核心赠款将利用优秀的基本 国家眼科研究所的科学和临床研究专业知识通过提供重要的 资源和服务分为以下4个不同的核心。 1.生物统计学核心将为视觉研究社区提供专门的统计专业知识， 加州大学圣地亚哥分校有几个常见的分析主题和统计问题可以有效地解决 并通过拥有熟悉眼科研究的专业生物统计学家来分析视力相关数据， 并确保结果的严谨性和透明度。 2.动物结构和功能核心将提供共享仪器和技术人员提供协助 在动物的眼部结构成像和功能成像中。 3.计算眼科核心提供i）专用高性能CPU和GPU 计算资源ii）计算机程序员，iii）机构软件许可证和iv）安全文件 共享和备份服务，以支持UCSD的细胞，动物和人类视觉研究。 4.组织处理和组织学核心提供眼组织的快速表征， 组织学、免疫组织化学和共聚焦显微镜检查，由辅助仪器和一名技术员进行 其熟悉眼解剖学和正确处理眼组织所需的技术。 这些核心将提高UCSD视觉科学家的效率，生产力和影响力， 个人调查员无法获得的核心服务。核心赠款基础设施和资源 还利用每个参与研究者的专业知识，加强多学科合作， 整个UCSD视觉研究社区的利益。

SUMMARY Overall The overall purpose of the Vision Research Core Grant is to provide core services and resources to enhance and accelerate the productivity and impact of the vision research community at University of California, San Diego. Specifically, the Vision Research Core grant will leverage the outstanding basic science and clinical research expertise of National Eye Institute funded investigators by providing important resources and services organized into the following 4 distinct cores. 1. The Biostatistics Core will provide dedicated statistical expertise for the vision research community at UCSD. There are several common analysis themes and statistical issues that can be addressed effectively and efficiently by having a dedicated biostatistician familiar with eye research to analyze vision related data and to ensure rigor and transparency of the results. 2. The Animal Structure and Function Core will provide shared instrumentation and a technician to assist with ocular structural imaging and functional imaging in animals. 3. The Computational Ophthalmology core provides i) dedicated high-performance CPU and GPU computing resources ii) a computer programmer, iii) institutional software licenses and iv) secure file sharing and backup services to support UCSD's cellular, animal and human vision research studies. 4. The Tissue Processing and Histology Core provides rapid characterization of eye tissue with respect to histology, immunohistochemistry and confocal microscopy by supporting instrumentation and a technician who is familiar with ocular anatomy and techniques required to properly process ocular tissues. These cores will improve the efficiency and productivity and impact of UCSD vision scientists by providing core services that are unavailable to individual investigators. The core grant infrastructure and resources also leverages the expertise of each participating investigator to enhance multidisciplinary collaboration for the benefit of the entire UCSD vision research community.