Developmental Research Program

节目描述 发展研究计划一直是最有价值和最富有成效的孢子之一 件.卵巢癌创新转化研究概念的发展至关重要， 这取决于试点项目是否有灵活的供资。SPORE发展的目的 研究计划是鼓励和发展具有转化潜力的研究项目， 卵巢癌的发病率和死亡率或提高生存率和生活质量。实验室和临床 研究项目如属翻译性质，便可获得资助。孢子的一部分 每年划拨预算（直接费用90 000美元）用于支持试点项目。资金限制为40，000美元， 年，每个项目。我们将提供高达10,000美元的额外卵巢孢子机构匹配 资金，以便在每个项目40，000美元的水平上提供资金。至少有三个项目已经并将继续 每年资助。资助最初为一年，可续期一年;现在申请人将有 可以选择一次申请两年的资助。2年提案的第二年供资将取决于 并会与新的拨款申请竞争。 发展研究计划的目的是资助任何年龄的研究人员有前途的项目 他们的工作可能不仅仅集中在卵巢癌上，但他们提出了创新的转化研究， 卵巢癌，可以成为完整的孢子项目或竞争成功的资金以外的 孢子。 发展研究计划的目标如下： 宣传卵巢癌转化研究试点项目启动资金的可用性。 确定具有创新性并具有显著降低卵巢癌发病率潜力的项目 和死亡率，或提高生存率和生活质量。 鼓励SPORE内的科学家之间以及与SPORE外的科学家之间的合作 环境 帮助潜在的试点项目研究人员定义和阐明转化研究的目标和步骤 需要将研究成果转化为人类应用。 使用内部和外部评审员选择竞争性研究提案以获得资金， 的搜索. 为SPORE机构的研究人员和其他选定地点的科学家提供发展资金。 密切监督并与发展项目研究人员合作，以帮助他们实现翻译研究目标。 管理一个灵活的计划，其中展示承诺的试点项目遵循三个课程之一：a）他们将被资助一年，如果特别有希望，可能会有额外的支持; B）他们将被提升为完整的SPORE项目;或c）将鼓励研究者申请R 01或其他同行评审的研究支持。没有发挥其潜力的发展项目将被终止。

Program Description The Developmental Research Program has been one of the most valuable and productive of the SPORE components. The development of innovative translational research concepts in ovarian cancer is critically dependent on the availability of flexible funding for pilot projects. The purpose of the SPORE Developmental Research Program is to encourage and develop research projects with translational potential that will reduce ovarian cancer incidence and mortality or improve survival and quality of life. Both laboratory and clinical research projects are eligible for funding, provided that they are translational in nature. A portion of the SPORE budget ($90,000 in direct costs) is allocated annually to support pilot projects. Funding is limited to $40,000 per year per project. We will provide up to an additional $10,000 from the Ovarian SPORE Institutional Matching funds in order to fund at the $40,000 per project level. At least three projects have been and will continue to be funded annually. Funding was initially f o r i year and was renewable for another year; now applicants will have the option to apply for 2 years of funding at once. Second-year funding of a 2-year proposal will be dependent on the progress made in the first year, and the proposal will compete with new applications for funding. The purpose of the Developmental Research Program is to fund promising projects by investigators of any age whose work may not focus exclusively on ovarian cancer, but who propose innovative translational studies of ovarian cancer that could become full SPORE projects or compete successfully for funding outside of the SPORE. The objectives of the Developmental Research Program are as follows: Publicize the availability of start-up funding for pilot projects in ovarian cancer translational research. Identify projects that are innovative and have significant potential for reducing ovarian cancer incidence and mortality or for improving survival and quality of life. Encourage collaborations among scientists within the SPORE and with scientists outside the SPORE environment. Help potential pilot project investigators define and articulate translational research goals and the steps required to beneficially translate research into application in humans. Select competing research proposals for funding using internal and external reviewers applying specific criteria. Provide developmental funding for investigators in the SPORE institution and scientists at other selected sites. Closely monitor and work with the Developmental Project investigators to assist them in achieving their translational research goals. Administer a flexible program in which pilot projects that demonstrate promise follow one of three courses: a) They will be funded for another year, possibly with additional support if particularty promising; b) They will be elevated to full SPORE projects; or c) Investigators will be encouraged to apply for an R01 or other peer-reviewed research support. Developmental projects that do not reach their potential will be terminated.