Claude D. Pepper Older Americans independence Center

UM-OAIC的任务是确定和评估以运动学习为基础的运动康复的机制和效果，该康复侧重于功能的恢复和维持，以及预防使患有慢性疾病的老年人面临残疾风险的功能下降。这将通过以下方式实现：1)开展基础和临床转化研究，研究老年人在神经运动、肌肉、代谢和心血管功能领域中与流行疾病相关的功能障碍的潜在机制；2)将这些发现从实验室转化为临床，设计新颖有效的基于运动学习的运动干预/情绪，以供社区实施；3)支持PES、DPs和外部资助的研究项目，研究残疾的潜在机制、康复过程以及功能的恢复和维持；4)通过导师式的研究培训、生物统计学、信息学和转化研究、应用生理学和组织机制研究核心，促进多学科青年教师的职业发展，成为独立的老年学术科学家；以及活动功能和神经运动可塑性在研究工作组（rwg）中合作，该工作组将指导从开始到发表以及通过社区翻译的研究。为促进学者的职业发展，中心提供导师培训和教学课程；PESC提出了5项新的干预措施；一项新的rc3dp研究了平衡训练降低跌倒风险的机制。UM-OAIC多学科研究团队有能力和动力通过开发创新的、基于运动学习的运动康复项目来改变临床康复实践，这些项目将改善残疾老年人的功能和临床结果，促进他们独立生活。我们乐观地认为，UMOAlC对老年病学和康复研究的转化方法将通过开发创新的、可行的康复干预措施来改变临床实践，从而促进美国老年人的功能独立性和健康。

The mission of the UM-OAIC is to determine and evaluate the mechanisms and efficacy of motor learning based exercise rehabilitation that focuses on the restoration and maintenance of function, and the prevention of the functional decline that puts older adults with chronic diseases at risk for disability. This will be accomplished by 1) conducting basic and clinical translational research that examines the mechanisms underlying the functional impairments associated with prevalent diseases in older people across the domains of neuromotor, muscular, metabolic and cardiovascular function; 2) translating these findings from the lab to the clinic to design novel efficacious motor learning based exercise interv/entions for community implementation; 3) supporting PES, DPs and externally funded grants examining the mechanisms underlying disability, the processes of recovery and the restoration and maintenance of function and 4) fostering the career development of junior faculty from multiple disciplines into independent geriatric academic scientists through mentor- based research training, Research Cores in Biostatistics, Informatics and Translational Research, Applied Physiology and Tissue Mechanisms, and Mobility Function and Neuromotor Plasticity collaborate in Research Working Groups (RWGs) which will guide studies from inception to publication and through to community translation. The RCDC provides mentor-based training with didactic courses to promote the career development of RCDC Scholars; a PESC proposes 5 novel interventions; and a novel RC3 DP examines mechanisms by which balance training reduces fall risk. The UM-OAIC multidisciplinary research team has the skills and motivation to change clinical rehabilitation practice by developing innovative, motor learning based exercise rehabilitation programs that will improve the functional and clinical outcomes of older people with disabilities to promote independent living. We are optimistic that the UMOAlC's translational approach to geriatrics and rehabilitation research will change clinical practice by developing innovative, feasible rehabilitation interventions that will promote the functional independence and the health of older Americans.