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Claude D. Pepper Older Americans independence Center

克劳德·D·佩珀美国老年人独立中心

基本信息

批准号：
8316152
负责人：
ANDREW P GOLDBERG
金额：
$ 107.71万
依托单位：
UNIVERSITY OF MARYLAND BALTIMORE
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-09-15 至 2016-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8316152
关键词：
Acute Aerobic Aging American Balance training Biometry Cardiovascular Physiology Cardiovascular system Caring Cessation of life Chronic Disease Clinic Clinical Communities Community Practice Disabled Persons Discipline Disease Elderly Environment Event Exercise Faculty Fatigue Fostering Functional disorder Funding Geriatrics Goals Grant Health Hip Fractures Impaired cognition Impairment Independent Living Informatics Institutionalization Interdisciplinary Study Intervention Laboratory Finding Life Expectancy Maintenance Mentors Metabolic Metabolic syndrome Mission Morbidity - disease rate Motivation Muscle Myocardial Infarction Outcome Phenotype Physiological Physiology Prevention Preventive Medicine Process Publications Randomized Clinical Trials Recovery Rehabilitation Outcome Rehabilitation Research Rehabilitation therapy Research Research Design Research Training Risk Scientist Stroke Tissues Training Translating Translational Research Translations base bench to bedside career development clinical practice community intervention design disability fall risk functional decline functional disability functional restoration improved innovation motor learning neuropsychological novel prevent programs public health priorities rehabilitation science rehabilitation strategy research clinical testing restoration sarcopenia skills translational approach working group

项目摘要

The mission of the UM-OAIC is to determine and evaluate the mechanisms and efficacy of motor learning based exercise rehabilitation that focuses on the restoration and maintenance of function, and the prevention of the functional decline that puts older adults with chronic diseases at risk for disability. This will be accomplished by 1) conducting basic and clinical translational research that examines the mechanisms underlying the functional impairments associated with prevalent diseases in older people across the domains of neuromotor, muscular, metabolic and cardiovascular function; 2) translating these findings from the lab to the clinic to design novel efficacious motor learning based exercise interv/entions for community implementation; 3) supporting PES, DPs and externally funded grants examining the mechanisms underlying disability, the processes of recovery and the restoration and maintenance of function and 4) fostering the career development of junior faculty from multiple disciplines into independent geriatric academic scientists through mentor- based research training, Research Cores in Biostatistics, Informatics and Translational Research, Applied Physiology and Tissue Mechanisms, and Mobility Function and Neuromotor Plasticity collaborate in Research Working Groups (RWGs) which will guide studies from inception to publication and through to community translation. The RCDC provides mentor-based training with didactic courses to promote the career development of RCDC Scholars; a PESC proposes 5 novel interventions; and a novel RC3 DP examines mechanisms by which balance training reduces fall risk. The UM-OAIC multidisciplinary research team has the skills and motivation to change clinical rehabilitation practice by developing innovative, motor learning based exercise rehabilitation programs that will improve the functional and clinical outcomes of older people with disabilities to promote independent living. We are optimistic that the UMOAlC's translational approach to geriatrics and rehabilitation research will change clinical practice by developing innovative, feasible rehabilitation interventions that will promote the functional independence and the health of older Americans.

UM-OAIC的使命是确定和评估基于运动学习的运动康复的机制和疗效，该运动康复的重点是恢复和维持功能，并防止使患有慢性病的老年人面临残疾风险的功能衰退。这将通过以下方式实现：1)进行基础和临床转化研究，检查与老年人常见疾病相关的神经运动、肌肉、代谢和心血管功能领域的功能损害的潜在机制；2)将这些发现从实验室转化到临床，为社区实施设计新的有效的基于运动学习的运动干预；3)支持PES、DPS和外部资助的赠款，研究残疾的潜在机制、康复过程以及功能的恢复和维持；4)通过以导师为基础的研究培训、生物统计学、信息学和翻译研究的研究核心、应用生理学和组织机制以及研究工作组(RWGs)中的行动功能和神经运动可塑性合作，促进来自多个学科的初级教师的职业发展，使其成为独立的老年学术科学家。RCDC提供以导师为基础的培训和授课课程，以促进RCDC学者的职业发展；PESC提出5种新的干预措施；新的RC3 DP研究平衡训练降低跌倒风险的机制。UM-OAIC多学科研究团队有能力和动力通过开发创新的、基于运动学习的运动康复计划来改变临床康复实践，这些计划将改善老年残疾人的功能和临床结果，以促进独立生活。我们乐观地认为，UMOAlC在老年病学和康复研究方面的翻译方法将通过开发创新、可行的康复干预措施来改变临床实践，从而促进美国老年人的功能独立和健康。