Claude D. Pepper Older Americans independence Center

克劳德·D·佩珀美国老年人独立中心

• 批准号: 8179917
• 负责人: ANDREW P GOLDBERG
• 金额: $ 108.78万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-15 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8179917
• 关键词: Claude; D.; Pepper; Older; Americans

The mission of the UM-OAIC is to determine and evaluate the mechanisms and efficacy of motor learning based exercise rehabilitation that focuses on the restoration and maintenance of function, and the prevention of the functional decline that puts older adults with chronic diseases at risk for disability. This will be accomplished by 1) conducting basic and clinical translational research that examines the mechanisms underlying the functional impairments associated with prevalent diseases in older people across the domains of neuromotor, muscular, metabolic and cardiovascular function; 2) translating these findings from the lab to the clinic to design novel efficacious motor learning based exercise interv/entions for community implementation; 3) supporting PES, DPs and externally funded grants examining the mechanisms underlying disability, the processes of recovery and the restoration and maintenance of function and 4) fostering the career development of junior faculty from multiple disciplines into independent geriatric academic scientists through mentor- based research training, Research Cores in Biostatistics, Informatics and Translational Research, Applied Physiology and Tissue Mechanisms, and Mobility Function and Neuromotor Plasticity collaborate in Research Working Groups (RWGs) which will guide studies from inception to publication and through to community translation. The RCDC provides mentor-based training with didactic courses to promote the career development of RCDC Scholars; a PESC proposes 5 novel interventions; and a novel RC3 DP examines mechanisms by which balance training reduces fall risk. The UM-OAIC multidisciplinary research team has the skills and motivation to change clinical rehabilitation practice by developing innovative, motor learning based exercise rehabilitation programs that will improve the functional and clinical outcomes of older people with disabilities to promote independent living. We are optimistic that the UMOAlC's translational approach to geriatrics and rehabilitation research will change clinical practice by developing innovative, feasible rehabilitation interventions that will promote the functional independence and the health of older Americans.

UM-OAIC 的使命是确定和评估基于运动学习的运动康复的机制和功效，重点是功能的恢复和维持，以及预防使患有慢性疾病的老年人面临残疾风险的功能衰退。这将通过以下方式实现：1）进行基础和临床转化研究，检查与老年人流行疾病相关的功能障碍的机制，涉及神经运动、肌肉、代谢和心血管功能领域； 2）将这些研究结果从实验室转化为临床，设计新颖有效的基于运动学习的运动干预/干预措施，供社区实施； 3) 支持 PES、DP 和外部资助的赠款，研究残疾的机制、康复过程以及功能的恢复和维持； 4) 通过基于导师的研究培训、生物统计学、信息学和转化研究、应用生理学和组织机制以及移动功能和 神经运动可塑性在研究工作组 (RWG) 中进行合作，该工作组将指导研究从开始到发表，直至社区翻译。 RCDC提供以导师为基础的培训和教学课程，以促进RCDC学者的职业发展； PESC 提出 5 项新颖的干预措施；新颖的 RC3 DP 研究了平衡训练降低跌倒风险的机制。 UM-OAIC 多学科研究团队拥有通过开发基于运动学习的创新运动康复计划来改变临床康复实践的技能和动力，这些计划将改善残疾老年人的功能和临床结果，促进独立生活。我们乐观地认为，UMOAlC 的老年病学和康复研究转化方法将通过开发创新、可行的康复干预措施来改变临床实践，从而促进美国老年人的功能独立和健康。