Administration Core

日常生活中最引人注目的特征包括在我们的环境中导航的能力和 相互交流。这些功能是生存的基础，但也是第一批 在患病或老化的神经系统中遇到麻烦。罗切斯特大学拥有一套NIH支持的 致力于感觉、运动、整合和细胞机制的研究项目 基础导航和通信。研究范围从分子和遗传方法到 清醒动物对人类感知的细胞神经生理学，包括强烈的翻译和 临床要素。这些特点为我们的P-30导航中心提供了一个引人注目的框架 和传播科学(CNCS)。在过去的授权期内，CNCS现在处于稳定状态 这超出了所有人的预期，很大程度上是因为一位敬业的、 敬业的教职员工，合作共享的核心服务，强有力的咨询和质量保证 流程、基础设施和社区，事实证明对新的协作和新的 调查人员。 CNCS允许调查人员高效地分享昂贵、耗时、必要但繁琐的 和创新的研究服务。CNCS包括三个核心：1)要巩固的人类主体核心 协调各项目科目的招募、筛选、日程安排和数据库管理；2)a) 研究服务核心，包括一个组织学和成像股(组织准备、图像分析和 1个电子/机械车间(修理和建造实验室部件和设备)、1个 动物研究股(突变和基因敲除准备、饲养和筛选)和蛋白质组学股 (专门的蛋白质分析)；和3)技术和计算核心，包括实验室技术股 (用于刺激和行为控制、数据采集和数据分析的自动化实验室系统)和 计算股，以支持个人电脑和网络操作、软件库、网络支持和工作人员培训。 一些服务单位与神经生物学和解剖学系、视觉中心共享支持 科学(NEI-P30)和两个项目(NIA-P01和NINDS-P01)。CNCS利用我们的 与生俱来的大学生态，通过杰出的核心人员和 专用空间内的设施。所有核心和单元都高效运行，并平衡 既提供所需的服务，有时也提供平凡的服务，以及新颖和创新的解决方案 转变为明天的能力。这将确保在 强大的基础设施，丰富了我们的研究工作效率，促进了 研究人员，吸引新的教职员工和学生加入我们的研究使命，促进进一步的机构 支持，并最终为社区和国家的健康做出贡献。

The most compelling features of daily life include the ability to navigate through our environment and to communicate with each other. These functions are fundamental to survival, but are also among the first to encounter trouble in the diseased or aging nervous system. The University of Rochester holds a set of NIHsupported research programs dedicated to the sensory, motor, integrative, and cellular mechanisms underlying navigation and communication. Research ranges from molecular and genetic approaches to cellular neurophysiology in awake animals to human perception, and includes strong translational and clinical elements. These characteristics provide a compelling framework for our P-30, Center for Navigation and Communication Sciences (CNCS). New this past grant period, the CNCS is now operating at a steadystate that exceeds all expectations, largely due to committed leadership matched by a dedicated and engaged faculty and staff, cooperative and shared core services, a strong advisory and quality assurance process, and an infrastructure and community that has proven attractive to new collaborations and new investigators. The CNCS allows investigators to efficiently share costly, time-consuming, essential but cumbersome, and innovative research services. The CNCS includes three cores: 1) a Human Subjects Core to consolidate and coordinate the recruitment, screening, scheduling, and databasing of subjects across projects; 2) a Research Services Core that includes a Histology & Imaging Unit (tissue preparation, image analysis & reconstruction), an Electronic/Mechanical Shop (repair and construction of lab components and devices), an Animal Research Unit (mutant and knockout preparations, husbandry and screening), and a Proteomics Unit (specialized protein analysis); and 3) a Technology and Computation Core, including a Lab Technology Unit (automated lab systems for stimulus and behavioral control, data acquisition, and data analysis) and a Computation Unit to support PC and network operations, software library, web support, and staff training. Some service units share support with the Department of Neurobiology & Anatomy, the Center for Visual Science (an NEI-P30), and two program projects (an NIA-P01 and an NINDS-P01). The CNCS exploits our inherently collegiate ecology and augments our lab capabilities through outstanding core personnel and facilities in dedicated space. All cores and units operate efficiently and balance the combined goals of providing both needed though sometimes mundane services as well as novel and innovative solutions that transform into tomorrow's capabilities. This ensures high-quality, efficient, and diverse services to all, in a robust infrastructure that enriches the productivity of our research, promotes collaborations among investigators, attracts new faculty and students to our research mission, facilitates further institutional support, and ultimately contributes to the health of the community and the nation.