Administration Core

行政核心

• 批准号: 8292218
• 负责人: GARY D PAIGE
• 金额: $ 3.2万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-23 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8292218
• 关键词: Aging; Anatomy; Animal Experimentation; Animals; Arts; Behavior Control; Characteristics; Clinical; Collaborations; Commit; Communication; Communities; Community Health; Computer software; Data Analyses; Devices; Ecology; Electrical Engineering; Electronics; Elements; Engineering; Ensure; Environment; Equilibrium; Faculty; Goals; Grant; Histology; Human; Human Resources; Image; Image Analysis; Internet; Knock-out; Laboratories; Leadership; Libraries; Life; Link; Mechanics; Mission; Molecular Genetics; Motor; National Institute of Neurological Disorders and Stroke; Nervous system structure; Neurobiology; Perception; Preparation; Process; Productivity; Protein Analysis; Proteomics; Research; Research Infrastructure; Research Personnel; Resources; Schedule; Science; Screening procedure; Sensory; Services; Solutions; Stimulus; Students; Supervision; System; Technology; Time; Training; Universities; awake; college; computerized data processing; data acquisition; design; expectation; experience; human subject; image reconstruction; innovation; instrumentation; meetings; mutant; neurophysiology; novel; operation; programs; quality assurance; ranpirnase; repaired; tissue preparation; vision science

The most compelling features of daily life include the ability to navigate through our environment and to communicate with each other. These functions are fundamental to survival, but are also among the first to encounter trouble in the diseased or aging nervous system. The University of Rochester holds a set of NIHsupported research programs dedicated to the sensory, motor, integrative, and cellular mechanisms underlying navigation and communication. Research ranges from molecular and genetic approaches to cellular neurophysiology in awake animals to human perception, and includes strong translational and clinical elements. These characteristics provide a compelling framework for our P-30, Center for Navigation and Communication Sciences (CNCS). New this past grant period, the CNCS is now operating at a steadystate that exceeds all expectations, largely due to committed leadership matched by a dedicated and engaged faculty and staff, cooperative and shared core services, a strong advisory and quality assurance process, and an infrastructure and community that has proven attractive to new collaborations and new investigators. The CNCS allows investigators to efficiently share costly, time-consuming, essential but cumbersome, and innovative research services. The CNCS includes three cores: 1) a Human Subjects Core to consolidate and coordinate the recruitment, screening, scheduling, and databasing of subjects across projects; 2) a Research Services Core that includes a Histology & Imaging Unit (tissue preparation, image analysis & reconstruction), an Electronic/Mechanical Shop (repair and construction of lab components and devices), an Animal Research Unit (mutant and knockout preparations, husbandry and screening), and a Proteomics Unit (specialized protein analysis); and 3) a Technology and Computation Core, including a Lab Technology Unit (automated lab systems for stimulus and behavioral control, data acquisition, and data analysis) and a Computation Unit to support PC and network operations, software library, web support, and staff training. Some service units share support with the Department of Neurobiology & Anatomy, the Center for Visual Science (an NEI-P30), and two program projects (an NIA-P01 and an NINDS-P01). The CNCS exploits our inherently collegiate ecology and augments our lab capabilities through outstanding core personnel and facilities in dedicated space. All cores and units operate efficiently and balance the combined goals of providing both needed though sometimes mundane services as well as novel and innovative solutions that transform into tomorrow's capabilities. This ensures high-quality, efficient, and diverse services to all, in a robust infrastructure that enriches the productivity of our research, promotes collaborations among investigators, attracts new faculty and students to our research mission, facilitates further institutional support, and ultimately contributes to the health of the community and the nation.

日常生活中最引人注目的特征包括在我们的环境中导航的能力， 互相交流这些功能是生存的基础，但也是第一个 在患病或老化的神经系统中遇到麻烦。罗切斯特大学拥有一套NIH支持的 致力于感觉、运动、整合和细胞机制的研究项目 基本的导航和通信。研究范围从分子和遗传方法， 细胞神经生理学在清醒的动物对人类的感知，并包括强大的翻译和 临床元素这些特点为我们的P-30导航中心提供了一个引人注目的框架 通信科学（CNCS）在过去的赠款期间，CNCS现在处于稳定状态 这超出了所有人的预期，主要是由于坚定的领导， 参与教职员工，合作和共享的核心服务，强大的咨询和质量保证 流程，基础设施和社区已被证明对新的合作和新的 investigators. CNCS允许调查人员有效地共享昂贵，耗时，必要但繁琐的， 创新的研究服务。CNCS包括三个核心：1）人类受试者核心， 并协调项目间受试者的招募、筛选、时间安排和数据库; 2）a 研究服务核心，包括组织学和成像单元（组织制备，图像分析和 重建），电子/机械车间（实验室组件和设备的维修和建造）， 动物研究单位（突变体和敲除制备、饲养和筛选）和蛋白质组学单位 （专门的蛋白质分析）;以及3）技术和计算核心，包括实验室技术单元 （用于刺激和行为控制、数据采集和数据分析的自动化实验室系统）和 计算股支持个人计算机和网络操作、软件库、网络支持和工作人员培训。 一些服务单位与神经生物学与解剖学系，视觉中心和神经科学中心共享支持。 科学（NEI-P30）和两个计划项目（NIA-P01和NINDS-P01）。CNCS利用我们的 固有的学院生态，并通过优秀的核心人员增强我们的实验室能力， 专用空间内的设施。所有核心和单元都高效运行，并平衡以下综合目标 提供所需的，虽然有时平凡的服务，以及新颖和创新的解决方案， 转化为明天的能力。这确保了高质量，高效，多样化的服务，在一个 强大的基础设施，丰富了我们的研究生产力，促进了合作， 研究人员，吸引新的教师和学生到我们的研究使命，促进进一步的机构 支持，并最终有助于社区和国家的健康。