Technology and Comp Core

技术与核心竞争力

• 批准号: 8094319
• 负责人: GARY D PAIGE
• 金额: $ 17.1万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-23 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8094319
• 关键词: Anatomy; Animal Experimentation; Animals; Behavior; Behavioral; Clinical; Collaborations; Communication; Communities; Consultations; Custom; Devices; Diagnostic; Disease; Educational process of instructing; Electronics; Engineering; Ensure; Environment; Equipment; Faculty; Fostering; Future; Goals; Growth; Histology; Human; Image; Image Analysis; Individual; Laboratories; Labyrinth; Maintenance; Mass Spectrum Analysis; Mechanics; Mediating; Modification; Molecular; Molecular Analysis; Molecular Biology; Molecular Genetics; Mus; Neurobiology; Otolaryngology; Outcome; Patients; Perception; Physiological; Population; Preparation; Process; Productivity; Protein Analysis; Proteins; Proteomics; Psychophysics; Publications; Research; Research Personnel; Rodent; Rodent Model; Sampling; Screening procedure; Services; Solutions; Structure; System; Techniques; Technology; Time; Tissues; base; design; digital; human subject; image processing; image reconstruction; improved; innovation; instrumentation; interest; member; mutant; neurophysiology; new technology; novel; programs; ranpirnase; reconstruction; relating to nervous system; repaired; technological innovation; tissue preparation; tool

The laboratories of the Core-Center are uniformly technologically sophisticated and automated. Further, the faculty are engaged in a broad range of approaches, from molecular biology to cellular neurophysiology to behavior and perception, and utilize a variety of animal subjects as well as humans and patients. These attributes form a common need for technical services across the Core-Center. The Research Services Core (RSC) provides four sets of key services. Each operates in complementary partnerships with other NIHsupported Centers and Programs, and with the Department of Neurobiology and Anatomy. This structure ensures the highest quality of services and facilities possible, while maximizing efficiency and economy. The Histology & Imaging Unit provides tissue preparation, image analysis and reconstruction technologies, An additional component is an Imaging Facility that includes digital and wet darkrooms that facilitate transforming research findings into figures and images for publication and teaching tools. All investigators in the Co re-Center that use animals have a need for histological services, and yet the need does not justify full-time commitments. A collective solution is ideal. The Electronic and Mechanical Shop provides essential services to all labs, given the common requirement for equipment repair and maintenance overtime, and modifications and construction of electronic and mechanical components and devices on a semi-regular basis. The Shop exploits modern automated design-build technologies routinely. New faculty have expanded cellular-molecular-genetic levels of inquiry within the CNCS, and these approaches entail the use of mouse and other rodent models, including mutant and genetically engineered populations. A new Animal Research Unit assists CNCS investigators using rodents with purchasing, husbandry, recordkeeping, and basic physiologic and diagnostic screening in support of their research goals. The new Proteomics Unit offers modern protein analysis technology and services, from design and consultation to purification strategies for proteins of interest and clinical sample analysis. The Unit also assists Pis in the preparation of materials mass spectrometry. The Units of the RSC provide sophisticated services across the Co re-Center that are well suited for a common and centralized structure and function. This Core offers a high quality and accessible set of services to CNCS faculty that enhances the productivity of our research and stimulates interactions across laboratories. The attractive environment produced in turn catalyzes technological and scientific collaboration, and attracts new investigators to our labs and research goals.

核心中心的实验室都是技术先进和自动化的。此外，本发明还 教师们从事广泛的方法，从分子生物学到细胞神经生理学 行为和感知，并利用各种动物科目以及人类和病人。这些 这些属性形成了整个核心中心对技术服务的共同需求。研究服务核心 (RSC)提供四大服务。每个机构都与其他NIH支持的机构建立互补的伙伴关系 中心和计划，并与神经生物学和解剖学系。这种结构 确保尽可能提供最高质量的服务和设施，同时最大限度地提高效率和经济效益。 组织学和成像部门提供组织准备、图像分析和重建 一个额外的组成部分是一个成像设施，包括数字和湿暗室， 促进将研究成果转化为数字和图像，用于出版和教学工具。所有 使用动物的核心中心的研究人员需要组织学服务，然而， 并不能证明全职工作是合理的。集体解决方案是理想的。电子和机械商店 为所有实验室提供必要的服务，考虑到设备维修和维护的共同要求 加班费，以及电子和机械部件和设备的修改和施工， 半定期的基础上。The Shop定期利用现代自动化设计-建造技术。新教师 在CNCS中扩大了细胞分子遗传学水平的调查，这些方法需要 使用小鼠和其他啮齿动物模型，包括突变体和基因工程群体。一个新 动物研究部门协助CNCS调查人员使用啮齿动物进行采购、饲养、记录， 和基本的生理和诊断筛选，以支持他们的研究目标。新 蛋白质组学部门提供现代蛋白质分析技术和服务，从设计和咨询到 用于感兴趣的蛋白质和临床样品分析的纯化策略。该股还协助私人侦探在 材料的制备质谱。 RSC的各部门在整个核心中心提供复杂的服务，非常适合 共同和集中的结构和功能。此核心提供了一套高质量和可访问的服务 CNCS教师，提高了我们的研究生产力，并刺激跨 laboratories.所产生的有吸引力的环境反过来又促进了技术和科学合作， 并吸引新的研究人员到我们的实验室和研究目标。