Health Effects of Adolescent Water Pipe Smoking with & without Cigarette Smoking

青少年吸水烟对健康的影响

• 批准号: 8232773
• 负责人: Thomas Norbert Templin
• 金额: $ 44.08万
• 依托单位: WAYNE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8232773
• 关键词: Address; Adolescence; Adolescent; Adult; Age; American; American Lung Association; Arabs; Asia; Asthma; Binding; Breathing; Carbon Monoxide; Characteristics; Chest; Cigarette; Cigarette Smoker; Communities; Comparative Study; Coronary heart disease; Cotinine; Dose; Erythrocytes; Ethnic Origin; Frequencies; Gender; Goals; Guidelines; Health; Height; High Prevalence; Home environment; Human; Intervention; Joints; Knowledge; Laboratories; Laboratory Study; Life; Link; Lung; Lung diseases; Malignant - descriptor; Malignant Neoplasms; Measures; Michigan; Middle East; Nicotine; Non-Malignant; Northern Africa; Outcome; Participant; Particulate; Pattern; Perinatal; Pipe smoker; Policies; Public Health; Pulmonary Function Test/Forced Expiratory Volume 1; Pulmonary function tests; Recording of previous events; Relative (related person); Reporting; Research; Respiratory Tract Infections; Respiratory physiology; Risk; Saliva; Schedule; Schools; Smoke; Smoking; Smoking History; Smoking Status; Societies; Spirometry; Students; Surveys; Testing; Time; Tobacco; Tobacco smoking; Tobacco use; Toxicant exposure; United States; World Health Organization; Youth; cigarette smoking; design; high school; hookah; non-smoker; older men; pipe smoking; pulmonary function; respiratory; response; smoking intervention; social; trend; twelfth grade

DESCRIPTION (provided by applicant): The World Health Organization and the American Lung Association both report a growing trend in the use of water pipes for tobacco smoking by youth around the world and in the U.S.A. Water pipe smoking by adults has been shown to be associated with many of the same health problems that result from cigarette smoking, (e.g., poor lung function,malignant and non-malignant lung disease) but little is known about the health effects of water pipe smoking in adolescents. If early and potentially serious health effects can be identified in adolescence from water pipe smoking with or without cigarette smoking, the benefit to the public health message would be enormous. Spirometric measures of lung function provide an objective and noninvasive means to identify lung damage in adolescents. A few studies have reported impaired lung function in adolescent cigarette smokers but none have examined the health effects of water pipe smoking in adolescents. One cannot assume the lung and health consequences of water pipe and cigarette smoking are the same as they are performed in different ways with different doses and with different tobacco types. In addition, they produce different volumes of smoke, particulates, and nicotine. Our hypothesis is that WP smoking significantly diminishes lung function and contributes to general health problems in adolescents. Our corollary hypothesis is that adolescents who smoke the water pipe will show differing patterns, frequency, and intensity of product use, yet manifest similar or worse health problems than those found in cigarette smokers. The proposed three-year study will be conducted in three public high schools in southeastern Michigan. These schools were selected because our prior research found a high prevalence of water pipe smoking among students with Middle Eastern and non-Middle Eastern heritage. A detailed water pipe and cigarette smoking "life time" history of tobacco use will be obtained from 3000 high school seniors. The 300 students with the longest and most severe water pipe and/or cigarette smoking histories will be asked to participate in saliva cotinine testing (to verify their smoking status) and pulmonary function testing. These students will be compared with nonsmokers (n = 300) matched on key pulmonary function variables (age, gender, height, and ethnicity). The analyses will estimate the effects of smoking status on each of the spirometry outcomes (FEV1, FVC, FEV1/FVC, FEV25-75). We will determine the joint effect of smoking both water pipes and cigarettes and the independent effects of each. The relative effects of each type of smoking will be examined in a dose response analysis and by ranking the four smoking status groups on each of the spirometric parameters. Patterns and predictors of WP and cigarette smoking initiation and progression will be identified. PUBLIC HEALTH RELEVANCE: Water pipe smoking (WPS) is a very old tradition in the Middle East, North Africa, and Asia, which is now growing in use around the world and in the United States. It is especially dangerous for adolescents whose lungs are still developing. This study will examine the effects of adolescent WPS on lung function and general health. In addition, we will determine the patterns and predictors of this form of tobacco use.

描述（由申请人提供）：世界卫生组织和美国肺脏协会均报告称，​​世界各地和美国青少年使用水烟斗吸烟的趋势呈增长趋势。成年人吸水斗已被证明与吸烟引起的许多相同的健康问题有关（例如肺功能差、恶性和非恶性肺病），但人们对青少年吸水斗对健康的影响知之甚少。如果可以在青春期发现吸烟或不吸烟的情况下吸水烟对健康的早期和潜在的严重影响，那么对公共卫生信息的好处将是巨大的。肺功能的肺活量测量提供了一种客观且无创的方法来识别青少年的肺损伤。一些研究报告了青少年吸烟者的肺功能受损，但没有一项研究研究了青少年吸烟对健康的影响。人们不能假设吸水烟和吸烟对肺部和健康的影响是相同的，因为它们以不同的方式、不同的剂量和不同的烟草类型进行。此外，它们还会产生不同量的烟雾、颗粒物和尼古丁。 我们的假设是，WP 吸烟会显着降低肺功能，并导致青少年出现一般健康问题。我们的推论假设是，吸水烟的青少年会表现出不同的产品使用模式、频率和强度，但表现出与吸烟者相似或更严重的健康问题。 拟议的为期三年的研究将在密歇根州东南部的三所公立高中进行。之所以选择这些学校，是因为我们之前的研究发现，中东和非中东裔学生吸水烟的比例很高。将从 3000 名高中生那里获得详细的水烟和吸烟“一生”吸烟史。 300名有最长和最严重吸水烟和/或吸烟史的学生将被要求参加唾液可替宁测试（以验证他们的吸烟状况）和肺功能测试。这些学生将与关键肺功能变量（年龄、性别、身高和种族）相匹配的非吸烟者（n = 300）进行比较。 分析将估计吸烟状况对每项肺活量测定结果（FEV1、FVC、FEV1/FVC、FEV25-75）的影响。我们将确定同时吸水烟和香烟的联合效应以及各自的独立效应。将在剂量反应分析中检查每种类型吸烟的相对影响，并通过对每个肺活量参数对四个吸烟状态组进行排名来检查。将确定 WP 和吸烟开始和进展的模式和预测因素。 公共健康相关性：吸水烟 (WPS) 在中东、北非和亚洲是一种非常古老的传统，目前在世界各地和美国越来越流行。对于肺部仍在发育的青少年来说尤其危险。本研究将探讨青少年 WPS 对肺功能和总体健康的影响。此外，我们将确定这种烟草使用形式的模式和预测因素。

项目成果

Health Effects Reported by Adolescent Water Pipe and/or Cigarette Smokers Compared to Nonsmokers.

与不吸烟者相比，青少年水烟和/或香烟吸烟者报告的健康影响。

• DOI: 10.1016/j.jadohealth.2018.08.027
• 发表时间: 2019
• 期刊: The Journal of adolescent health : official publication of the Society for Adolescent Medicine
• 作者: Rice,VirginiaHill;Templin,ThomasN;Harden,JanetK;Jenuwine,ElizabethS;Abdulhamid,Ibrahim;Hammad,Adnan
• 通讯作者: Hammad,Adnan