China Health and Retirement Longitudinal Study

描述（由申请人提供）：本申请请求支持2011年秋季在中国健康与退休纵向研究（CHARLS）中采集的静脉血生物标志物样本的测定。这是对现有R01赠款的竞争性修订，该赠款将支持CHARLS小组的前两个国家波的收集，第一个是 第一次在2011年，第二次在2013年。中国健康与退休纵向研究（CHARLS）是一项针对中国老年人的调查，由北京大学国家发展研究院（中国经济研究中心）和中国卫生部疾病预防控制中心（CDC）共同开展。它是基于成员年龄在45岁及以上的家庭的样本。它旨在建立一个高质量的公共微型数据库，提供从社会经济状况到健康状况的广泛信息，以满足中国老年人科学研究的需要。CHARLS还旨在与健康和退休研究（HRS）系列研究中的其他研究进行比较。在本申请所要求的支持下，我们将分析在国家研究的第1波中从约17，600人中采集的静脉血，用于炎症水平、糖化血红蛋白、血糖、血脂和肾功能指标。这将允许将这些生物标志物的水平与中国的社会经济、行为和背景变量进行比较，与其他国际调查的水平和与其他变量的联系进行比较。 公共卫生相关性：中国健康与退休纵向研究（CHARLS）将丰富老龄化研究的国际格局。CHARLS紧密遵循世界上现有的健康与退休研究的格式和内容，以便为学者提供进行比较研究以及研究中国特殊情况的能力。查尔斯的前两次全国性浪潮定于2011年和2013年举行。这一竞争性修订将使CHARLS能够增加第一波数据收集期间收集的静脉血样本中重要生物标志物的结果。

DESCRIPTION (provided by applicant): This application requests support for the assay of venous blood biomarker samples now collected in the fall of 2011 in the China Health and Retirement Longitudinal Study (CHARLS). This is a competing revision to an existing R01 grant that will support the collection of the first two national waves of the CHARLS panel, the first was fielded in 2011 and the second in 2013. The China Health and Retirement Longitudinal Study (CHARLS) is a survey of the elderly in China, run by the National School for Development (China Center for Economic Research) at Peking University, together with the Chinese Center for Disease Control and Prevention (CDC) in the Ministry of Health. It is based on a sample of households with members aged 45 years and older... It is designed to produce a high quality public micro-database, which can provide a wide range of information from socio-economic status to health conditions, to serve the needs of scientific research on the elderly in China. CHARLS is also designed to allow comparisons with other studies in the Health and Retirement Study (HRS) family of studies. With the support requested in this application we will assay venous blood collected in wave 1 of the national study from approximately 17,600 people for indicators of the level of inflammation, glycosylated hemoglobin, plasma glucose, lipids, and kidney functioning This will allow the comparison of levels of these biomarkers with socioeconomic, behavioral and contextual variables within China, with the comparison of levels and links with other variables other international surveys. PUBLIC HEALTH RELEVANCE: The China Health and Retirement Longitudinal Study (CHARLS) will enrich the international landscape of aging studies. CHARLS follows closely the format and content of existing Health and Retirement Studies around the world in order to provide the capability for scholars to engage in comparative studies as well as studies of the special conditions in China. The first two national waves of CHARLS are scheduled for 2011 and 2013. This competitive revision will enable CHARLS to add results on important biomarkers from venous blood samples collected during the first wave of data collection.