Activity, Gait, and Efficacy (AGE II): Functional Limitations and Quality of Life

活动、步态和功效 (AGE II)：功能限制和生活质量

• 批准号: 8286247
• 负责人: Edward McAuley
• 金额: $ 36.17万
• 依托单位: UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-15 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8286247
• 关键词: Adopted; Adoption; Adult; Age; American; Attention; Behavior; Censuses; Centers for Disease Control and Prevention (U.S.); Effectiveness; Elderly; Elements; Equilibrium; Evaluation; Foundations; Gait; Growth; Health; Health Status; Home environment; Illinois; Independent Living; Intervention; Life; Life Expectancy; Maintenance; Measures; Mediating; Mediation; Mediator of activation protein; Mental Health; Modeling; Modern Medicine; National Institute on Aging; Outcome Measure; Participant; Pathway interactions; Patient Self-Report; Performance; Physical Function; Physical activity; Population; Public Health; Quality of life; Randomized; Recruitment Activity; Research; Sampling; Self Efficacy; Testing; Time; Translating; United States; aged; base; compare effectiveness; design; digital; fitness; flexibility; follow-up; healthy aging; human old age (65+); improved; physical conditioning; primary outcome; programs; prospective; public health relevance; secondary outcome; sedentary; statistics

DESCRIPTION (provided by applicant): This application proposes to test the effectiveness of a DVD-delivered home-based physical activity intervention targeting flexibility, toning, and balance (FTB) activities when compared with an attention control condition to reduce functional limitations and enhance functional performance and quality of life (QOL) in older adults. It is hypothesized that participation in this 6-month FTB program will improve functional fitness and balance, reduce functional limitations, and improve overall quality of life at the end of the trial and at 6-month follow-up. A further aim is to longitudinally test the mediators of physical activity effects on functional limitations and quality of life. A final aim is to implement REAIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) principles into the design and evaluation of the proposed study in order to determine the potential public health impact of delivering physical activity via DVD media. The aims and objectives of the proposed application are consistent with the National Institute on Aging's strategies for improving the health and quality of life of older Americans. Additionally, our reach and generalizability of findings are likely to be considerable. We propose to recruit and randomly assign 250 older (65+ years) low-active adults from across central Illinois to the FTB condition to be delivered in the home by DVD or an attention control condition receiving a healthy aging DVD and equivalent contact time. The control condition will be offered the FTB program following the 6- month follow-up assessments. Primary outcome measures are functional performance and functional limitations with secondary outcomes being self-efficacy, physical activity, health status, and quality of life. All measured will be assessed at baseline, six and twelve months. All hypotheses will be tested using latent growth curve modeling within a covariance modeling framework. PUBLIC HEALTH RELEVANCE: The public health relevance of this application is considerable as it targets an element of the population that is largely sedentary and suffers from unprecedented levels of functional limitations, factors that have significant implications for compromised quality of life and independent living. By adopting a REAIM approach to the design and implementation we will be able to effectively improve the physical activity behavior of a broad class of older adults with few exclusionary criteria to study entry enhancing reach and generalizability of findings.

描述（由申请人提供）：本申请旨在测试DVD递送的以灵活性、调节和平衡（FTB）活动为目标的基于家庭的身体活动干预与注意力控制条件相比的有效性，以减少老年人的功能限制并增强功能表现和生活质量（QOL）。假设参加这项为期6个月的FTB计划将改善功能健康和平衡，减少功能限制，并改善试验结束时和6个月随访时的整体生活质量。另一个目的是纵向测试身体活动对功能限制和生活质量影响的介质。最终目的是将REAIM（范围、有效性、采用、实施和维护）原则应用到拟议研究的设计和评价中，以确定通过DVD媒体进行体力活动的潜在公共卫生影响。拟议申请的目的和目标与国家老龄问题研究所改善美国老年人健康和生活质量的战略一致。此外，我们的研究结果的范围和普遍性可能是相当大的。我们建议招募并随机分配250名来自伊利诺伊州中部的老年（65岁以上）低活动成年人到FTB条件下，通过DVD或注意力控制条件在家中提供，接受健康的老龄化DVD和同等的接触时间。在6个月的随访评估后，将为对照组提供FTB计划。主要结局指标为功能表现和功能限制，次要结局为自我效能、体力活动、健康状况和生活质量。将在基线、6个月和12个月时对所有测量值进行评估。将在协方差建模框架内使用潜在增长曲线建模对所有假设进行检验。 公共卫生相关性：这一应用的公共卫生相关性相当大，因为它针对的是一个基本上久坐不动并遭受前所未有的功能限制的人群，这些因素对生活质量和独立生活有重大影响。通过采用REAIM方法的设计和实施，我们将能够有效地改善广泛的老年人的体育活动行为，几乎没有排除标准来研究进入增强研究结果的可及性和普遍性。