Activity, Gait, and Efficacy (AGE II): Functional Limitations and Quality of Life

活动、步态和功效 (AGE II)：功能限制和生活质量

• 批准号: 8064346
• 负责人: Edward McAuley
• 金额: $ 36.84万
• 依托单位: UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-15 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8064346
• 关键词: Adopted; Adoption; Adult; Age; American; Attention; Behavior; Censuses; Centers for Disease Control and Prevention (U.S.); Effectiveness; Elderly; Elements; Equilibrium; Evaluation; Foundations; Gait; Growth; Health; Health Status; Home environment; Illinois; Independent Living; Intervention; Life; Life Expectancy; Maintenance; Measures; Mediating; Mediation; Mediator of activation protein; Mental Health; Modeling; Modern Medicine; National Institute on Aging; Outcome Measure; Participant; Pathway interactions; Patient Self-Report; Performance; Physical Function; Physical activity; Population; Public Health; Quality of life; Randomized; Recruitment Activity; Research; Sampling; Self Efficacy; Testing; Time; Translating; United States; aged; base; compare effectiveness; design; digital; fitness; flexibility; follow-up; healthy aging; human old age (65+); improved; physical conditioning; primary outcome; programs; prospective; public health relevance; secondary outcome; sedentary; statistics

DESCRIPTION (provided by applicant): This application proposes to test the effectiveness of a DVD-delivered home-based physical activity intervention targeting flexibility, toning, and balance (FTB) activities when compared with an attention control condition to reduce functional limitations and enhance functional performance and quality of life (QOL) in older adults. It is hypothesized that participation in this 6-month FTB program will improve functional fitness and balance, reduce functional limitations, and improve overall quality of life at the end of the trial and at 6-month follow-up. A further aim is to longitudinally test the mediators of physical activity effects on functional limitations and quality of life. A final aim is to implement REAIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) principles into the design and evaluation of the proposed study in order to determine the potential public health impact of delivering physical activity via DVD media. The aims and objectives of the proposed application are consistent with the National Institute on Aging's strategies for improving the health and quality of life of older Americans. Additionally, our reach and generalizability of findings are likely to be considerable. We propose to recruit and randomly assign 250 older (65+ years) low-active adults from across central Illinois to the FTB condition to be delivered in the home by DVD or an attention control condition receiving a healthy aging DVD and equivalent contact time. The control condition will be offered the FTB program following the 6- month follow-up assessments. Primary outcome measures are functional performance and functional limitations with secondary outcomes being self-efficacy, physical activity, health status, and quality of life. All measured will be assessed at baseline, six and twelve months. All hypotheses will be tested using latent growth curve modeling within a covariance modeling framework. PUBLIC HEALTH RELEVANCE: The public health relevance of this application is considerable as it targets an element of the population that is largely sedentary and suffers from unprecedented levels of functional limitations, factors that have significant implications for compromised quality of life and independent living. By adopting a REAIM approach to the design and implementation we will be able to effectively improve the physical activity behavior of a broad class of older adults with few exclusionary criteria to study entry enhancing reach and generalizability of findings.

描述（由申请人提供）：本申请旨在测试以 DVD 形式提供的家庭身体活动干预措施的有效性，该干预措施针对灵活性、强健性和平衡性 (FTB) 活动，与注意力控制条件相比，以减少老年人的功能限制并提高功能表现和生活质量 (QOL)。据推测，参与这个为期 6 个月的 FTB 计划将改善功能健康和平衡，减少功能限制，并提高试验结束时和 6 个月随访时的整体生活质量。进一步的目标是纵向测试身体活动对功能限制和生活质量影响的中介因素。最终目标是将 REAIM（范围、有效性、采用、实施和维护）原则落实到拟议研究的设计和评估中，以确定通过 DVD 媒体提供身体活动的潜在公共健康影响。拟议应用程序的目的和目标与国家老龄化研究所改善美国老年人健康和生活质量的战略一致。此外，我们的研究结果的影响范围和普遍性可能相当大。我们建议招募并随机分配来自伊利诺斯州中部的 250 名老年人（65 岁以上）低活跃成年人到 FTB 条件下，通过 DVD 在家中交付或接受健康老年 DVD 和同等接触时间的注意力控制条件。控制条件将在 6 个月的跟踪评估后提供 FTB 计划。主要结果指标是功能表现和功能限制，次要结果是自我效能、身体活动、健康状况和生活质量。所有测量都将在基线、六个月和十二个月时进行评估。所有假设都将在协方差建模框架内使用潜在增长曲线建模进行测试。 公共卫生相关性：该应用程序的公共卫生相关性相当大，因为它针对的是大部分久坐且遭受前所未有的功能限制的人群，这些因素对生活质量和独立生活的影响具有重大影响。通过采用 REAIM 方法进行设计和实施，我们将能够有效地改善广大老年人的身体活动行为，而几乎没有排除标准来研究进入，从而提高研究结果的影响范围和普遍性。