SWAN NJ-Quantitative and Qualitative cohort Research

项目主任/首席调查员(最后、第一、中间)：桑托罗，纳内特 项目总结(见说明)： 《全国妇女健康研究》是一项多种族、多地点的中年妇女研究项目。 已经活跃了10多年的美国。天鹅-新泽西队列的社会经济水平最低 状况，基线上最差的健康指标，并遭受了大量后续行动的损失和障碍 继续研究。尽管有大量的人员流失，但新泽西州的天鹅-西语裔女性的比例仍然最高 发生代谢综合征和2型糖尿病，并报告更多的症状和更多的不良反应 与天鹅队列的其他成员相比，更年期过渡期的症状。我们也认识到有必要 为了更好地了解我们关于西班牙裔女性的数据与队列中其他人在以下方面的关键差异 补充和替代药物的使用以及每日总热量摄入量的报告。因此，我们建议3 具体目标，将只关注其余拉美裔队列成员(n=150)，并寻求融入 调查的定量和定性方法：目标1将继续收集定量数据；实物 我们拉美裔队列成员的测量、血液和简短调查数据以及SCID访谈，称为 5月，总体来说，天鹅FV假说是可行的，并特别检验了西班牙裔女性将成为 更有可能：a.获得代谢综合征和糖尿病；b.报告更多的血管舒缩症状和经历更多 然而，与天鹅的其他族裔相比，他们寻求治疗的频率较低。Aim 2将检查 西班牙裔队列和天鹅其他人之间的差异，以检验西班牙裔女性的假设：A.不 将更年期视为一种需要治疗的疾病；B.由于缺乏，使用比人们认为的更多的CAM治疗 C.因缺乏种族适宜而少报的卡路里消耗量 调查中使用的食物选择。目标3将探索与更年期相关的态度和益处，调查 女性体验更年期症状的概念性视角，并调查和检查 通过使用叙述性访谈(定性的)，利用应对机制和实践，例如CAM和饮食 研究)与西班牙裔妇女的关系。 相关性(请参阅说明)： 定量和定性方法的结合旨在最大限度地利用可以 从难以招募和留住的女性人群中获得，对她们来说，留住是一种 这是一项挑战，并将为今后致力于研究拉美裔妇女混合群体的研究提供信息。 这些发现可以应用于在少数民族中进行临床研究所涉及的挑战。 项目/

Program Director/Principal Investigator (Last, First, Middle): SantOrO, Nanette PROJECT SUMMARY (See instructions): SWAN, the Study of Women's Health Across the Nation, is a multi-ethnic, multi-site study of mid life women in the United States that has been active for over 10 years. The SWAN-New Jersey cohort had the lowest socio-economic status, the poorest health indicators at baseline and has suffered from substantialloss to follow up and impediments to continued research. Despite substantial attrition, SWAN-New Jersey Hispanic women continue to have the highest rate of incident metabolic syndrome and type 2 diabetes, and report more symptoms with more adverse reactions to their symptoms over the menopause transition compared to the rest of the SWAN cohort. We have also recognized the need to better understand key discrepancies between our data on Hispanic women and the rest of the cohort with respect to the use of complementary and alternativemedicineand the reporting of total daily caloric intake. We thus propose 3 specific aims that will focus exclusively on the remaining Hispanic cohort members (n=150) and seek to integrate quantitative and qualitative methods of inquiriy: Aim 1 will continue to collect quantitative data;physical measurements, blood and abbreviated survey data and SCID interviewson our Hispanic cohort members to address as may overall SWAN FVhypotheses as are feasible and to test specificallythe hypothesies that Hispanic women will be more likely to: a. acquire metabolic syndrome and diabetes; b. report more vasomotor symptoms and experience greater distress from them yet seek medical treatment less frequently than other ethnic groups in SWAN . Aim 2 will examine discrepancies between the Hispaniccohort and the rest of SWAN to test the hypotheses that Hispanic women: a. do not view menopause as a medical conditionthat requires treatment; b. utlize more CAM treatment than believed due to lack of ethnically appropriate survey use and c. under-reported calories consumed due to a lack of ethnically appropriate food choices on the surveys used. Aim 3 will explore attitudesand benefits associated with menopause, investigate the conceptual perspective through which women experience menopausal symptoms, and investigate and examine what coping mechanisms and practices are utilized such as CAM and diet through the use of narrative interviews (qualitative research) with Hispanic women. RELEVANCE fSee instructions): The combination of quantitative and qualitative approaches is intended to maximize the information that can be obtained from a difficult-to-recruit and retain population of women for whom retention has been a challenge, and will serve to inform future research dedicated to study of a mixed group of Hispanic women. These findings can be applied to the challenges involved in conducting clinical research in ethnic minorities. PROJECT/