2011 Oxidative Stress and Disease Gordon Research Conference

描述（由申请人提供）：戈登研究会议（GRC）的氧化应激和疾病的目的是提供科学家从广泛的学科与氧化应激在各种疾病过程中的作用的最新研究成果，重点是共享机制。该研究会议自1999年以来每两年举行一次;它是GRC将于2011年组织的150多个会议的一部分，GRC是一个以其会议的高质量，前沿性而闻名的国际组织。虽然是一个相对年轻的GRC会议，但自十多年前成立以来，出席会议的人数稳步增长。2011年关于氧化应激和疾病的GRC将于2011年3月14日至18日在加利福尼亚州文图拉的喜来登四点/假日快捷酒店举行。本申请中描述的会议计划已围绕“氧化应激和疾病研究中的新兴研究领域”的主题进行了组装，这些研究领域最近共同改变了我们思考氧化应激对人类疾病中涉及的细胞机制的影响的方式。这些将包括氧化应激对例如表观遗传学、microRNA、干细胞和线粒体动力学的影响。与这些新研究领域相关的发现反过来可能会影响基础研究转化为氧化应激相关疾病干预措施的方式。本次戈登研究会议将汇集与氧化应激和疾病的各个方面相关的广泛兴趣的国际领先专家，并将创建一个高质量的科学论坛，讨论基本机制的最新发现及其转化实施为旨在治疗新疾病的干预措施。此外，在本次会议的历史上第一次，会前戈登凯南研究研讨会将由博士后水平的初级研究人员组织。研讨会期间的活动将面向初级调查员，目的是：（1）为他们提供有关氧化应激和疾病的共同机制的基本背景，以最大限度地提高他们对将在随后的会议上讨论的科学的理解，（2）从该领域的专家那里获得关于他们正在进行的研究项目的反馈，以及（3）促进他们与该科学界高级成员的互动，以促进该领域初级和高级研究人员之间的网络联系。我们完全期待本次会议参与者之间的科学讨论，研究会谈，海报会议和其他非正式互动将有助于推进我们对氧化应激相关人类疾病所涉及的新分子机制的理解，并将为开发旨在促进这些疾病新治疗方法的合作干预奠定基础。 公共卫生相关性：戈登研究会议氧化应激和疾病连同会前戈登凯南研究研讨会将汇集领导人在各种科学学科相关的氧化应激相关疾病的研究和初级研究人员构成未来一代的研究人员在这一领域。本次会议期间的科学报告，讨论和研讨会旨在扩大我们对氧化应激可能导致疾病过程的机制的理解。预计本次会议传统上特有的合议和合作气氛将为这组相关疾病的新疗法的智力开发和实施提供完美的环境。

DESCRIPTION (provided by applicant): The Gordon Research Conference (GRC) on Oxidative Stress and Disease is designed to provide scientists from a wide range of disciplines with the latest research findings on the role of oxidative stress in a variety of disease processes with emphasis on shared mechanisms. This research conference has been held every 2 years since 1999; it is part of over 150 conferences that will be organized in 2011 by the GRC, an organization internationally known for the high- quality, cutting edge nature of its meetings. Although a comparatively young GRC conference, attendance at the meeting has grown steadily since its inception over ten years ago. The 2011 GRC on Oxidative Stress and Disease will be held March 14-18, 2011 at the Sheraton Four Point/Holiday Inn Express in Ventura, CA. The program for the meeting described in this application has been assembled around the theme of "Emerging research areas in the study of oxidative stress and disease" which have recently collectively changed the way in which we think about the impact of oxidative stress on cellular mechanisms involved in human disease. These will include the impact of oxidative stress on, for example, epigenetics, microRNAs, stem cells, and mitochondrial dynamics. Findings associated with these novel areas of research are in turn likely to affect the manner in which basic research is translated into interventions for oxidative stress-related disorders. This Gordon Research Conference will bring together leading international experts with a broad range of interests related to diverse aspects of oxidative stress and disease and will create a high quality scientific forum for discussion of the latest findings on basic mechanisms and their translational implementation into interventions aimed at novel disease therapies. In addition, for the first time in the history of this conference, a pre-conference Gordon-Kenan Research Seminar will be organized by junior investigators at the postdoctoral level. Activities during the Seminar will be oriented to junior investigators and are intended to: (1) provide them with the basic background on common mechanisms involved in oxidative stress and disease necessary to maximize their understanding of the science which will be discussed in the subsequent conference, (2) receive feedback on their ongoing research projects from experts in the field, and (3) facilitate their interaction with senior members of this scientific community to promote networking between junior and more senior researchers in the field. We fully anticipate that the scientific discussions, research talks, poster sessions, and other informal interactions between the participants of this conference will contribute to advancing our understanding of novel molecular mechanisms involved in oxidative stress- related human disease and will set the basis for the development of collaborative interventions aimed at promoting new therapeutic treatments for these disorders. PUBLIC HEALTH RELEVANCE: The Gordon Research Conference on Oxidative Stress and Disease together with the pre- meeting Gordon Kenan Research Seminar will bring together leaders in a variety of scientific disciplines relevant to the study of oxidative stress-related disorders and junior investigators constituting the future generation of researchers in this field. The scientific presentations, discussions and workshops during this conference are designed to expand our understanding of the mechanisms by which oxidative stress may contribute to disease processes. It is anticipated that the collegial and cooperative atmosphere that has traditionally characterized this conference will provide the perfect setting for the intellectual development and implementation of novel therapeutics for this set of related diseases.