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TAS::75 0872::TAS UTMB-NHLBI PROTEOMIC CENTER FOR AIRWAY INFLAMMATION

TAS::75 0872::TAS UTMB-NHLBI PROTEOMIC CENTER FOR AIRWAY INFLAMMATION
塔斯马尼亚州::75 0872::塔斯马尼亚州 UTMB-NHLBI 气道炎症蛋白质组学中心
批准号：
8320843
负责人：
ALEXANDER none KUROSKY
金额：
$214.09万
依托单位：
UNIVERSITY OF TEXAS MED BR GALVESTON
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-08-15 至 2015-08-14
来源：
https://reporter.nih.gov/project-details/8320843
关键词：
AsthmaBiological MarkersCellsChronic Obstructive Airway DiseaseDevelopmentDiagnosisDiagnosticDiseaseGoalsHypersensitivityInfectionLeadLeukocytesMeasuresMedicalNational Heart, Lung, and Blood InstitutePathway interactionsPeptidesPost-Translational Protein ProcessingProteinsProteomeProteomicsSeverity of illnessStructure of parenchyma of lungTechnologyTexasTherapeutic InterventionTissuesUniversitiesairway inflammationbaseclinical applicationdesigninnovationnew technologyoutcome forecastprognosticprotein expressionrespiratory virusstressortranslational study

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中文摘要
翻译
德克萨斯大学医学分部蛋白质组学中心的目标是利用全面和创新的蛋白质组学策略来研究细胞、组织和生物液中与过敏、哮喘、慢性阻塞性肺疾病和呼吸道病毒相关的呼吸道炎症相关的蛋白质表达水平和翻译后修饰。这些研究将导致新技术的发展，以提供对影响呼吸道炎症的蛋白质组的机制和功能的了解，并识别用于诊断和预后的重要生物标志物。
英文摘要
The goal of the University of Texas Medical Branch Proteomics Center is to utilize comprehensive and innovative proteomic strategies to investigate protein expression levels and post-translational modifications in cells, tissues, and biofluids associated with airway inflammation related to allergy, asthma, COPD, and respiratory viruses. These studies will lead to the development of new technologies to provide a mechanistic and functional understanding of proteomes impacting on airway inflammation, and to identify important biomarkers for diagnosis and prognosis.
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TAS::75 0872::TAS UTMB-NHLBI PROTEOMIC CENTER FOR AIRWAY INFLAMMATION
NHLBI Research Diversity Program at UTMB
NHLBI Research Diversity Program at UTMB
NHLBI Research Diversity Program at UTMB
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