The Maya Angelou Center for Health Equity

糖尿病是美国（US）死亡和残疾的主要原因。2011年发表的最新估计表明，约有2600万美国人患有糖尿病，约占美国人口的8.3%。另有7900万美国人患有糖尿病前期，这使他们面临患2型糖尿病的高风险。糖尿病的公共卫生负担在大多数种族和少数民族群体中更为明显。非裔美国人和西班牙裔美国人的2型糖尿病及其相关并发症（包括死亡率）患病率较高，这是北卡罗来纳州和美国最大的种族/少数民族群体。尽管在国家糖尿病预防和控制研究中取得了成功，但人们对如何在“真实的世界”环境中充分实施和采用这些研究和其他研究的结果，以使最易受这种常见和昂贵疾病影响的人群受益，仍然缺乏了解。最近在联邦一级强调以社区为基础的转化研究，特别是强调转化科学知识以影响社区的“T4”研究，这可能是解决这些差距的一个关键方面。这一办法要求在进行文化上适当的研究方面受过充分培训的科学家与社区内的代表共同努力。对于拟议的COE，Maya Angelou健康公平中心将制定和实施多管齐下的方法，总体重点是转换循证的生活方式策略，以消除糖尿病预防和控制中的健康差异。 该中心将实现以下目标，这些目标与将生活方式方法转化为消除糖尿病差异的总体目标有关：（1）设计和开展两项以社区为基础的干预研究，重点是糖尿病预防和控制。

Diabetes mellitus is a leading cause of death and disability in the United States (US). Recent estimates published in 2011 indicate that about 26 million Americans have diabetes, or about 8.3% of the US population. An additional 79 million Americans have pre-diabetes, placing them at high risk for developing type 2 diabetes. The public health burden of diabetes is even more pronounced in most racial and ethnic minority groups. The prevalence of type 2 diabetes and its associated complications, including mortality, are higher for African Americans and Hispanics, the largest racial/ethnic minority groups in North Carolina and the US. Despite the successes seen in national diabetes prevention and control studies, there is a glaring lack of understanding in the ways in which the findings of these and other studies can be adequately implemented and adopted in "real world" settings to provide benefit to the populations that are most vulnerable to this common and costly disease. The recent emphasis on community-based and translational research at the federal level, especially "T4" research, which emphasizes the translation of scientific knowledge to impact the community, can be a key aspect to addressing these disparities. This approach requires a concerted effort between scientists adequately trained in conducting culturally appropriate research and representatives within the community. For the proposed COE, the Maya Angelou Center for Health Equity will develop and implement a multi-pronged approach with the overall focus on translating evidence-based, lifestyle strategies to eliminate health disparities In diabetes prevention and control. The MACHE COE will achieve the following aims pertinent to the overall goal of translating lifestyle approaches for eliminating diabetes disparities: (1) Design and conduct two community-based intervention studies focusing on diabetes prevention and control.