Mood, Physiological Arousal, and Alcohol Use

情绪、生理唤醒和饮酒

• 批准号: 8453159
• 负责人: Rachel Lynn Tomko
• 金额: $ 3.4万
• 依托单位: UNIVERSITY OF MISSOURI-COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-19 至 2014-09-18
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8453159
• 关键词: Address; Affect; Affective; Alcohol abuse; Alcohol consumption; Alcohols; Arousal; Autonomic nervous system; Awareness; Behavior; Behavioral; Borderline Personality Disorder; Characteristics; Communities; Coupled; Data; Data Analyses; Data Collection; Diagnosis; Disease; Disinhibition; Electronics; Emotional; Emotions; Environment; Evaluation; Fellowship; Goals; Heart Rate; Hour; Individual; Intervention; Journals; Laboratories; Lead; Learning; Life; Literature; Measurement; Measures; Methods; Modeling; Moods; Nature; Negative Reinforcements; Nervous System Physiology; Outpatients; Participant; Patient Self-Report; Pattern; Physiological; Physiology; Population; Psychopathology; Psychophysiology; Punishment; Reporting; Research; Research Training; Rewards; Risk; Risk Factors; Sampling; Stimulus; Stress; Testing; Time; Training; Translational Research; alcohol related problem; alcohol use disorder; approach behavior; base; career; diaries; drinking; driving behavior; emotion regulation; endophenotype; experience; heart rate variability; high risk; innovative technologies; meetings; negative mood; programs; response

DESCRIPTION (provided by applicant): This project will examine the relation between mood, autonomic hyper-arousal, and alcohol use in real-time, and determine whether autonomic hyper-arousal responses to standard stimuli in the laboratory are related to affect-alcohol relations in daily life. Method Using ambulatory physiological and self-report assessments, participants with difficulties in emotion regulation (i.e., meet criteria for borderline personalit disorder) and community controls will provide information regarding mood and drinking over the course of a week. Autonomic hyper-reactivity will also be assessed in the laboratory, in order to provide a comparison for real-time data. Long-Term Objectives Results from this project will inform negative reinforcement models of alcohol use and help identify physiological endophenotypes for alcohol use disorders. Training Aims The fellowship applicant will learn about autonomic nervous system functioning, analysis of psychophysiological data, analysis of intensive longitudinal data, and will gain experience communicating findings from this study in appropriate scientific journals. This will prepare the applicant for a career using translational research to study physiological and affective risk factors for alcohol use. PUBLIC HEALTH RELEVANCE: The proposed project will help identify subjective and autonomic factors that increase risk for alcohol-related problems. Thus, this project may influence preventative and intervention efforts by educating the public regarding specific emotional and autonomic states that may lead to alcohol abuse. With increased awareness of specific risk factors, individuals can make better behavioral decisions regarding alcohol use.

描述（由申请人提供）：本项目将实时检查情绪，自主神经过度觉醒和酒精使用之间的关系，并确定实验室中对标准刺激的自主神经过度觉醒反应是否与日常生活中的情感-酒精关系有关。方法采用动态生理和自我报告评估，参与者在情绪调节困难（即，符合边缘人格障碍的标准）和社区控制将提供一周内有关情绪和饮酒的信息。还将在实验室中评估自主神经高反应性，以提供实时数据的比较。长期目标本项目的结果将为酒精使用的负强化模型提供信息，并有助于识别酒精使用障碍的生理内表型。奖学金申请人将学习自主神经系统功能，心理生理数据分析，密集的纵向数据分析，并将获得在适当的科学期刊上交流本研究结果的经验。这将为申请人的职业生涯做好准备，使用转化研究来研究酒精使用的生理和情感风险因素。 公共卫生相关性：拟议的项目将有助于确定增加酒精相关问题风险的主观和自主因素。因此，该项目可能会影响预防和干预工作，教育公众关于特定的情绪和自主状态，可能会导致酗酒。随着对特定风险因素的认识的提高，个人可以在饮酒方面做出更好的行为决定。