Project 6. Ecological Momentary Assessment of Emotional Regulation

项目6.情绪调节的生态瞬时评估

• 批准号: 8278012
• 负责人: Timothy J Trull
• 金额: $ 31.2万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8278012
• 关键词: Acute; Address; Affect; Affective; Alcohol abuse; Alcohol consumption; Alcohol or Other Drugs use; Alcoholism; Alcohols; Antisocial Personality Disorder; Attenuated; Behavior; Biological Models; Blood alcohol level measurement; Body Weight; Borderline Personality Disorder; CCL7 gene; Calculi; Characteristics; Cigarette; Clinical; Cognitive Therapy; Comorbidity; Consumption; Data; Data Analyses; Data Collection; Disease; Disinhibition; Emotional; Emotions; Environment; Etiology; Event; Exhibits; Foundations; Frequencies; Funding; General Population; Grant; Impulsive Behavior; Impulsivity; Individual; Individual Differences; Lead; Life; Limb structure; Maintenance; Mental disorders; Modeling; Moods; Negative Reinforcements; Odds Ratio; Outpatients; Participant; Patients; Pattern; Play; Population; Positive Reinforcements; Prevention; Process; Progress Reports; Psychological reinforcement; Recreation; Regulation; Reporting; Research; Research Personnel; Research Project Grants; Risk; Role; Sampling; Self-Injurious Behavior; Self-control as a personality trait; Smoke; Smoking; Symptoms; Testing; Time; Tobacco use; Training; alcohol effect; alcohol use disorder; base; clinically significant; comparison group; coping; design; drinking; effective therapy; emotion regulation; hangover; hedonic; interest; negative mood; population based; positive emotional state; positive mood; response; sex; social; theories; trait; treatment strategy

This study extends currently ongoing research on both drinking and smoking (current Project 6) using ecological momentary assessment (EMA) to examine the use of alcohol with and without conjoint smoking to regulate emotions, and the effects of these regulation strategies on subsequent mood. We add a comparison group of Borderline Personality Disorder (BPD) patients. BPD exhibits high comorbidity with alcohol use disorders (AUDs) in both clinical and population-based samples. Cardinal symptoms of BPD, impulsivity and affective instability, are central constructs in theories of AUD etiology, so BPD represents a type of "model system" for studying the role of emotion regulation and disordered self-control in the genesis of AUD. We will collect EMA data from both random and event-based (e.g., drinking, smoking) assessments to address our aims. We will test the following hypotheses: (1) drinking episodes in BPD patients will be presaged by both positive and negative moods; drinking in non-affected controls (CON) will be presaged by positive but not negative moods; impulsivity will moderate these mood-substance use relations. (2) BPD patients' drinking episodes will be associated with heavier consumption (sex and body weight adjusted) than CON; group differences will be moderated by both affective instability and by impulsivity. Drinks consumed will be moderated by number of cigarettes in both groups. (3) Alcohol consumption's effect on mood will be characterized by both positive and negative reinforcement; smoking will attenuate the degree of reinforcement due to acute cross-tolerance effects in both groups. In BPD patients, underlying affective instability will attenuate the duration of alcohol-related, salutary effects on mood. (4) Negative post-drinking effects of alcohol on mood will be larger in BPD patients than controls because of additive effects of hedonic rebound effects of alcohol and negative affectivity in BPD patients; smoking will increase these effects in both groups. This study will provide important information about the role mood dysregulation plays in the etiology and maintenance of AUD, and how impulsivity and smoking may interact with mood dysregulation to lead to increased drinking. These results will have implications for both prevention and treatment of alcohol problems.

这项研究扩展了目前正在进行的关于饮酒和吸烟的研究(当前项目6)，使用 生态瞬时评估(EMA)，以检查酒精与吸烟和不吸烟的使用情况 调节情绪，以及这些调节策略对后续情绪的影响。我们添加了一个比较 边缘人格障碍(BPD)患者组。BPD与饮酒表现出高度的共病 临床和基于人群的样本中的疾病(AUD)。BPD的主要症状，冲动和 情绪不稳定是AUD病因学理论中的核心概念，因此BPD代表了一种类型的“模型” 研究情绪调节和紊乱的自我控制在AUD发生中的作用。我们将 从随机和基于事件(如饮酒、吸烟)的评估中收集EMA数据，以解决我们的 目标。我们将检验以下假设：(1)BPD患者的饮酒发作将由以下两个因素预示 积极和消极的情绪；非受影响对照组(CON)的饮酒将由积极而不是 消极情绪；冲动会调节这些情绪-物质使用关系。(2)BPD患者饮酒情况 与CON；组相比，发作将与更多的消费(调整后的性别和体重)相关 情感上的不稳定和冲动都会缓和分歧。所消费的饮料将是 在两组中都受到香烟数量的影响。(3)饮酒对情绪的影响将是 同时具有积极和消极强化的特点；吸烟会减轻 两组均有急性交叉耐受强化作用。对于BPD患者，潜在的情感 不稳定会减弱酒精对情绪的有益影响的持续时间。(4)饮酒后阴性 酒精对BPD患者情绪的影响将比对照组更大，因为享乐的相加效应。 酒精和负性情感在BPD患者中的反弹效应；吸烟将在 两组都是。这项研究将提供重要的信息，关于情绪失调在 AUD的病因和维持，以及冲动和吸烟可能如何与情绪失调相互作用 导致饮酒量增加。这些结果将对酒精的预防和治疗产生影响。 有问题。