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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The BUSM Center for Biomedical Mass Spectrometry website (www.bumc.bu.edu/bucbm) links those of the MS Resource, the Cardiovascular Proteomics Center and the Shared Instrumentation Laboratory. The Boston University School of Medicine Mass Spectrometry Resource website (www.bumc.bu.edu/msr) remains a very useful point of contact with the community and is used to disseminate information about our projects. Information useful for present and potential collaborators, as well as educational material and meeting/seminar notices and lists of Resource publications and presentations are posted, updated and revised as necessary. A section of the website is devoted to the Boston University Data Analysis (B.U.D.A.) program that we are developing for handling data analysis and interpretation of the highly complex FTMS data. The website covers some of the relevant parts of the amyloid project with the list of transthyretin variants and the list of references wherein these genetic mutations are reported. The site also lists the current group members, addresses and contact information for alumni, and provides information on some of the research projects that have already been reported to the community. Material related to our graduate-level course "Mass Spectrometry, Proteomics, and Functional Genomics" is also posted. Links to other relevant sites are provided. The web site is regularly updated with the latest findings related to the MSR technical research and development projects and collaborative projects.
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Methods for measuring matrisome molecule similarity during disease processes
Methods for measuring matrisome molecule similarity during disease processes
  • 批准号:
    10580774
  • 项目类别:
  • 资助金额:
    $41.25万
  • 财政年份:
    2022
  • 负责人:
    JOSEPH ZAIA
  • 依托单位:
Methods for measuring matrisome molecule similarity during disease processes
  • 批准号:
    10330789
  • 项目类别:
  • 资助金额:
    $27.23万
  • 财政年份:
    2022
  • 负责人:
    JOSEPH ZAIA
  • 依托单位:
Methods for determination of glycoprotein glycosylation similarities among disease states
  • 批准号:
    10194553
  • 项目类别:
  • 资助金额:
    $42.08万
  • 财政年份:
    2019
  • 负责人:
    JOSEPH ZAIA
  • 依托单位:
国内基金
海外基金
基于聚金属氧酸盐对Amyloid蛋白的定点化学修饰及其在阿尔茨海默症治疗中的应用
  • 批准号:
    22077118
  • 项目类别:
    面上项目
  • 资助金额:
    63.0万元
  • 批准年份:
    2020
  • 负责人:
    高楠
  • 依托单位:
基于S1P通路探究Amyloid-β在干性年龄相关性黄斑变性中的作用
  • 批准号:
    81870666
  • 项目类别:
    面上项目
  • 资助金额:
    57.0万元
  • 批准年份:
    2018
  • 负责人:
    王海燕
  • 依托单位:
Amyloid-beta-PirB 相互作用介导小胶质细胞表型和功能变化参与AD进展的机制研究
  • 批准号:
    81601123
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    17.0万元
  • 批准年份:
    2016
  • 负责人:
    都瑾
  • 依托单位:
Beta-amyloid寡聚体特有的抗原表位多肽疫苗的研究
  • 批准号:
    30971012
  • 项目类别:
    面上项目
  • 资助金额:
    35.0万元
  • 批准年份:
    2009
  • 负责人:
    刘瑞田
  • 依托单位: