A QUANTITATIVE COMPARISON OF NIRS AND FMRI ACROSS MULTIPLE COGNITIVE TASKS

跨多个认知任务的 NIRS 和 FMRI 的定量比较

• 批准号: 8362914
• 负责人: Xu Cui
• 金额: $ 1.3万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362914
• 关键词: Adult; Age; Annual Reports; Back; Brain; Cognitive; Disadvantaged; Fingers; Functional Magnetic Resonance Imaging; Funding; Grant; Hemoglobin; Inferior; Judgment; Left; Magnetic Resonance; Magnetic Resonance Imaging; Measures; National Center for Research Resources; Near-Infrared Spectroscopy; Noise; Principal Investigator; Reading; Relative (related person); Research; Research Infrastructure; Resolution; Resources; Short-Term Memory; Signal Transduction; Source; Stimulus; Structure; Technology; United States National Institutes of Health; Visit; Visuospatial; abstracting; cost; male

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. INTRODUCTION: Near-infrared spectroscopy (NIRS) is an increasingly popular technology for studying brain function. NIRS offers several advantages relative to functional magnetic resonance imaging (fMRI), including the ability to measure concentration changes of both oxygenated and deoxygenated hemoglobin, finer temporal resolution, and ease of administration, as well as disadvantages, most prominently inferior spatial resolution, inability to directly measure signals from deep-brain structures, and decreased signal-to-noise ratio (SNR). In this study, we compared NIRS and fMRI signals to assess spatial and temporal similarities. METHODS: Thirteen healthy adults (mean age 27.9, age range 21-42, 6 males) underwent simultaneous NIRS and fMRI scanning while they completed four experimental paradigms: left finger tapping (tap), go/no-go (nog), judgment of line orientation (jlo), and an N-back working memory task using visuospatial stimuli (vis). We performed detailed comparisons of the signals in both temporal and spatial domains. To read about other projects ongoing at the Lucas Center, please visit http://rsl.stanford.edu/ (Lucas Annual Report and ISMRM 2011 Abstracts)

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 前言：近红外光谱(NIRS)是研究脑功能的一种日益流行的技术。近红外光谱 提供与功能磁共振成像(FMRI)相关的几个优势，包括测量 氧合和去氧血红蛋白的浓度变化，更好的时间分辨率，以及更容易 管理也有缺点，最突出的是空间分辨率较低，无法直接测量信号 并降低了信噪比(SNR)。在这项研究中，我们比较了近红外光谱和功能磁共振成像信号 以评估空间和时间的相似性。 方法：13名健康成人(平均年龄27.9岁，年龄21-42岁，6名男性)同时接受近红外光谱和功能磁共振成像。 扫描时完成四个实验范式：左手指敲击(TAP)、进行/不进行(NOG)、线条判断 定向(JLO)，以及使用视觉空间刺激(VIS)的N-back工作记忆任务。我们进行了详细的比较 在时间域和空间域中的信号。 要了解卢卡斯中心正在进行的其他项目，请访问http://rsl.stanford.edu/(卢卡斯年度报告和 ISMRM 2011年摘要)