INVESTIGATION OF CHARGE-TRANSFER COMPLEXES OF ORTHO- AND PARA- SEMIQUINONES

邻半醌和对半醌的电荷转移络合物的研究

• 批准号: 8364028
• 负责人: DMITRIY TIPIKIN
• 金额: $ 3.82万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8364028
• 关键词: Albumins; Biological; Charge; Complex; Cyclodextrins; Fingerprint; Funding; Grant; Investigation; Libraries; National Center for Research Resources; Optics; Principal Investigator; Quercetin; Research; Research Infrastructure; Resources; Source; Structure; Technology; Time; United States National Institutes of Health; Work; charge transfer complex; cost; quantum chemistry; semiquinone; tool

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. High field EPR is a useful tool for investigating change transfer complex formation between unsubstituted o-semiquinones and different organic compounds (quercetin, cyclodextrin, albumin) The formation of charge transfer complexes was verified by observation of the optical spectrum of the charge transfer band. The high-field EPR spectra reveal for the first time a well-resolved g-tensor with a unique fingerprint for every type of complex. Subsequent work will use high-field EPR and quantum chemistry in order to calculate the exact structure of the complex in order to develop a spectral library for identifying various biological molecules containing charge transfer complexes.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 高场EPR是一种有用的工具，用于研究未取代的O-链氨喹酮与不同有机化合物（槲皮素，环糊精，白蛋白）之间的变化转移复合物的形成，通过观察电荷传递带的光谱验证了电荷传递复合物的形成。 高场EPR光谱首次揭示了解决各种复合物的独特指纹的精确的G量。随后的工作将使用高场EPR和量子化学，以计算复合物的确切结构，以开发光谱文库，以识别包含电荷转移复合物的各种生物分子。