HEARING IN MICE AND CHICKENS

小鼠和鸡的听力

• 批准号: 8365803
• 负责人: Edwin W Rubel
• 金额: $ 0.65万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365803
• 关键词: Biological; Biology; Cessation of life; Cochlear nucleus; Funding; Fungal Genome; Grant; Lead; Methods; Mus; National Center for Research Resources; Neurons; Newborn Animals; Principal Investigator; Research; Research Infrastructure; Resources; Signal Pathway; Source; Synapses; United States National Institutes of Health; cost; critical period; deprivation; genetic analysis; mature animal; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We will continue investigating the intercellular and intracellular signaling pathways that lead to neuronal death (or survival) following the elimination of excitatory synaptic input to the mammalian cochlear nucleus. A major initiative during the current grant period has been to use modern genetic analysis methods to begin assessing the biological mechanisms underlying differential responses of neonatal and adult animals to afferent deprivation (a critical period) of the mouse cochlear nucleus.

这个子项目是利用这些资源的众多研究子项目之一