Evaluation of a Lifestyle Intervention for Employees with Prediabetes

描述(由申请人提供)：在美国，大约40%的人口患有某种高血糖状况。工作场所干预措施为向糖尿病前期患者提供公共卫生干预提供了一个有希望的框架，因为工作场所在他们成年后的大部分时间里覆盖了很大一部分人口。通过工作场所获得长期跟踪和支持的机会可能比通过诊所或社区项目更大。雇员和雇主都有维护劳动力健康和控制医疗费用的既得利益。因此，这项研究的目的是评估俄亥俄州立大学(OSU)18-65岁糖尿病前期成年人(n=76)工地干预与常规护理的影响。俄亥俄州立大学是美国第二大公立大学，拥有一流的医学中心。参与者将被随机分配到工作地点进行为期16周的以小组为基础的生活方式干预，或接受常规护理。这项为期16周的小组干预改编自糖尿病预防计划，强调减少饮食脂肪和能量摄入，以及每周至少150分钟的适度体力活动。将确定干预对体重(主要结果)、空腹血糖、血脂、血压、体重参数、饮食摄入量(通过食物频率问卷评估)、体力活动、生活质量以及与解决问题和目标设定理论相关的结构的影响，并在干预后和3个月的随访中与常规护理进行比较。这项研究的结果将使研究人员能够完善招聘策略和干预程序，为更大规模的转化性临床试验制定一项潜在的可持续的大学计划，用于前驱糖尿病患者。 公共卫生相关性：工作场所干预提供了一个有希望的框架，为糖尿病前期患者提供更多的护理，因为工作场所覆盖了很大一部分成年人口。旨在促进减肥的结构化生活方式干预的效果 并将预防2型糖尿病与平时护理进行比较，以确定。这些发现将被用来为员工提供有效的干预，并通过大学工作场所的环境来维持。

DESCRIPTION (provided by applicant): In the U.S., approximately 40% of the population has some hyperglycemic condition. Worksite interventions offer a promising framework for delivering public health interventions to people with prediabetes, since worksites reach a large segment of the population for most of their adult life. The opportunity for long-term follow-up and support may be greater through worksites than through clinic- or community-based programs. Both the employee and employer have a vested interest in maintaining the health of the workforce and controlling health care costs. Therefore, the purpose of this study is to evaluate the impact of a worksite intervention compared to usual care among adults aged 18-65 years with prediabetes (n=76) at The Ohio State University (OSU). OSU is the second largest public university in the U.S. and includes a premier medical center. Participants will be randomly assigned to either a 16-week, group-based, lifestyle intervention delivered at the worksite or to usual care. The 16-week group- based intervention, adapted from the Diabetes Prevention Program, emphasizes reduction in dietary fat and energy intake and at least 150 minutes/week of moderate physical activity. The impact of the intervention on percent change in weight (primary outcome), fasting glucose, lipid panel, blood pressure, weight parameters, dietary intake (via food frequency questionnaire assessment), physical activity, quality of life, and constructs related to problem solving and goal setting theories will be determined and compared to usual care post-intervention and at 3-month follow-up. The findings from this study will enable the investigators to refine recruitment strategies and intervention procedures to develop a potentially sustainable university-based program for employees with prediabetes for a larger translational clinical trial. PUBLIC HEALTH RELEVANCE: Worksite interventions offer a promising framework for delivering greater care to people with prediabetes, since worksites reach a large segment of the adult population. The effect of a structured lifestyle intervention designed to promote weight loss and prevent type 2 diabetes compared to usual care will be determined. The findings will be used to deliver an effective intervention to employees that can be sustained through university worksite settings.