Vanderbilt Training Program in Molecular and Genetic Epidemiology of Cancer

范德比尔特癌症分子和遗传流行病学培训计划

• 批准号: 8545121
• 负责人: DOUGLAS CORBETT HEIMBURGER
• 金额: $ 52.83万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-13 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8545121
• 关键词: Address; Applications Grants; Bioinformatics; Biology; Biometry; Blood; Cancer Center; Cancer Etiology; Chemistry; Cohort Studies; Communities; Complement; Complex; DNA; Data; Development; Discipline; Disease; Disease Marker; Doctor of Philosophy; Education; Educational Curriculum; Environment; Epidemiologic Studies; Epidemiologist; Epidemiology; Ethnic Origin; Exposure to; Faculty; Funding; Funding Agency; Future; Genetic; Genetic Predisposition to Disease; Genetic Research; Grant; Haplotypes; Home environment; Human Genetics; International; Journals; Knowledge; Laboratories; Lead; Life Cycle Stages; Malignant Neoplasms; Maps; Measures; Mentors; Methodology; Molecular Biology; Molecular Epidemiology; Molecular Genetics; Outcome; Paper; Participant; Peer Review; Persons; Population; Postdoctoral Fellow; Preparation; Publishing; Recording of previous events; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Technics; Research Training; Resources; Saliva; Sampling; Science; Scientist; Solid; Surveys; Technology; Tissues; Training; Training Programs; Training and Education; Tumor Tissue; United States; United States National Institutes of Health; Urine; Work; Writing; anticancer research; base; cancer epidemiology; career; design; experience; frontier; genetic epidemiology; human DNA sequencing; interest; lifestyle factors; multidisciplinary; population based; programs; stem; symposium; tool

DESCRIPTION (provided by applicant): The rapid development and advancement of technologies and knowledge in molecular biology and genetics have led to major breakthroughs in cancer etiology research. While the field of cancer epidemiology is moving rapidly toward a new era where interdisciplinary and multidisciplinary collaborative research is the central theme, there is a severe shortage of scientists working at the interfaces of the epidemiology, molecular biology, and genetics. We propose to establish the Vanderbilt Training Program in Molecular and Genetic Epidemiology of Cancer (Vanderbilt-MAGEC) to equip postdoctoral fellows from a variety of disciplines with the methodological tools, practical laboratory and survey-research knowledge, and hands-on research and grant writing experience necessary to launch an independent career in the molecular and genetic epidemiology of cancer. The specific aims of the Vanderbilt MAGEC are: (1) To recruit exceptional, ethnically diverse candidates (2 MD and 5 PhD) with strong backgrounds in epidemiology, genetics, and/or biology. Candidates will be recruited locally and nationally from among persons who have recently completed PhD degrees in relevant sciences (particularly epidemiology, genetics, biology, chemistry, biostatistics) or MDs with serious interests in cancer epidemiology research. (2) To develop and deliver individualized didactic training tailored to complement each trainee's prior training background and launch them along their desired career paths (molecular or genetic epidemiology of cancer). Specific training will consist of courses, seminars, studios, and a journal club. (3) To establish a multidisciplinary mentor team for each trainee and integrate all trainees into NCI-funded cancer epidemiology research projects. (4) To evaluate the impact of the Vanderbilt-MAGEC by tracking short- and long-term outcomes. Expected short-term outcomes for all trainees include publishing papers in high-impact, peer-reviewed journals and submitting an NIH-quality grant proposal to an internal or external funding agency. Long-term outcomes will include cancer research career placements and NIH grant funding. This program, built upon an outstanding research and education training environment, an excellent body of researchers and educators, multiple, ongoing, cutting-edge research projects, exceptional data/biospecimen and population resources, and the rich history of interdisciplinary training at Vanderbilt, has an outstanding infrastructure and faculty to create an exemplary training program in the molecular and genetic epidemiology of cancer.

描述（申请人提供）：分子生物学和遗传学技术和知识的快速发展和进步，导致癌症病因学研究取得重大突破。虽然癌症流行病学领域正迅速走向一个以跨学科和多学科合作研究为中心主题的新时代，但在流行病学、分子生物学和遗传学的界面上工作的科学家严重短缺。我们建议建立范德比尔特癌症分子和遗传流行病学培训计划（Vanderbilt- magec），为来自不同学科的博士后提供方法学工具、实用实验室和调查研究知识，以及在癌症分子和遗传流行病学领域开展独立职业所需的动手研究和写作经验。