UNZA-Vanderbilt Training Partnership for HIV-NCD Research (UVP-2)

UNZA-范德比尔特 HIV-NCD 研究培训合作伙伴关系 (UVP-2)

• 批准号: 10240755
• 负责人: DOUGLAS CORBETT HEIMBURGER
• 金额: $ 28.93万
• 依托单位: UNIVERSITY OF ZAMBIA
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-06-15 至 2026-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10240755
• 关键词: Address; Africa; Africa South of the Sahara; Applications Grants; Career Choice; Chronic; Clinical; Collaborations; Detection; Doctor of Philosophy; Ensure; Epidemiology; Faculty; Fellowship; Funding; Goals; Grant; Growth; HIV; HIV therapy; Individual; Infrastructure; Institution; Investigation; Investments; Leadership; Mentorship; Modeling; Nutritional Study; Output; Persons; Prevention; Publications; Research; Research Ethics; Research Institute; Research Personnel; Research Training; Resource Development; Science; Scientist; Structure; Training; Training Programs; Universities; Visit; Writing; Zambia; antiretroviral therapy; base; career development; doctoral student; experience; implementation science; innovation; post-doctoral training; programs; research and development; sabbatical

As access to antiretroviral therapy for HIV has expanded in sub-Saharan Africa, millions of persons with HIV are surviving for decades on treatment, but they are developing chronic non-communicable disease (NCD) complications that require new science and new directions in prevention, detection, and treatment. Recogniz- ing that investigation and control of NCDs can be most effectively undertaken by highly trained local investiga- tors, the University of Zambia (UNZA)-Vanderbilt Partnership for HIV Nutrition Research Training (UVP-1) has supported PhD training for 11 Zambian scientists pursuing a wide range of HIV-NCD research and has helped strengthen the UNZA PhD program and the culture of mentorship at UNZA. We are now transitioning the UNZA-Vanderbilt Training Partnership for HIV-NCD Research (UVP-2) to UNZA as the prime institution. Our goals are to build UNZA’s research capacity by continuing our “sand- wich” model of PhD training and by using a similar model to develop a postdoctoral training program, with a view to creating a pipeline of independent UNZA scientists. We will also introduce new research training mechanisms and support structures at UNZA to ensure sustainability. Specifically, we will: 1. Train five (5) UNZA PhD students and four (4) UNZA postdoctoral scientists in advanced basic, clini- cal/translational, epidemiologic, and implementation sciences to address the complications and comorbidi- ties most relevant to lifelong HIV management in sub-Saharan Africa This aim focuses on training individuals. Both training programs will use our very successful “sandwich” for- mat with Africa- and U.S.-based components. Postdoctoral training is itself innovative for UNZA, and we will leverage Vanderbilt’s investments in postdoctoral research career development and intensive grant writing training through the Vanderbilt’s very successful Institute for Research Development and Ethics (VIRDE). 2. Strengthen UNZA’s capacity to train researchers, attract research funding, and generate high-impact research outputs across a broad range of HIV-NCD investigations This aim focuses on UNZA’s research training capacity. UVP-2 will support UNZA’s new postdoctoral fel- lowship mechanism by replicating key Vanderbilt career development resources at UNZA, principally those associated with successful grant applications, and three-month sabbaticals for four (4) UNZA Visiting Faculty Scholars at Vanderbilt, focused on developing collaborations and submitting grant applications. 3. Ensure and document UVP’s long-term impact under experienced UNZA leadership This aim focuses on program impact, which we will evaluate by tracking careers, grants, publications, re- search teams, and discoveries. The UNZA-Vanderbilt Partnership has proven highly efficient in catalyzing re- search capacity at UNZA. The addition of the new postdoctoral fellowship and the formation of infrastructure to increase UNZA’s grant support will usher in a new era of research growth and impact.

随着撒哈拉以南非洲获得艾滋病毒抗逆转录病毒疗法的机会增加， 在治疗中存活了几十年，但他们正在发展慢性非传染性疾病（NCD） 这些并发症需要新的科学和新的预防、检测和治疗方向。- - 认识到非传染性疾病的调查和控制可以由训练有素的地方卫生官员最有效地进行， 赞比亚大学（UNZA）-范德比尔特艾滋病毒营养研究培训伙伴关系（UVP-1） 支持对11名赞比亚科学家进行广泛的艾滋病毒-非传染性疾病研究的博士培训， 帮助加强了UNZA博士课程和UNZA的导师文化。 我们现在正在将UNZA-范德比尔特艾滋病毒-非传染性疾病研究培训伙伴关系（UVP-2）过渡到 UNZA作为主要机构。我们的目标是通过继续我们的“沙- “wich”博士培养模式，并利用类似模式开发博士后培养计划， 以期建立一个独立的UNZA科学家管道。我们还将介绍新的研究 确保可持续性。具体而言，我们将： 1.培训五（5）UNZA博士生和四（4）UNZA博士后科学家在先进的基础，临床， cal/translational，流行病学和实施科学，以解决并发症和合并症， 与撒哈拉以南非洲终身艾滋病毒管理最相关的联系 这一目标侧重于培训个人。两个培训项目都将使用我们非常成功的“三明治”- 与非洲-和美国-基于组件。博士后培训本身就是UNZA的创新，我们 将利用范德比尔特在博士后研究职业发展和密集的赠款写作方面的投资 通过范德比尔特非常成功的研究发展和道德研究所（VIRDE）进行培训。 2.加强UNZA培训研究人员、吸引研究资金和产生重大影响的能力 在广泛的艾滋病毒-非传染性疾病调查中的研究成果 这一目标的重点是非洲开发区的研究培训能力。UVP-2将支持UNZA的新博士后fel- 通过在UNZA复制关键的范德比尔特职业发展资源， 与成功申请补助金有关的补助金，以及四（4）名UNZA访问教师的三个月休假 范德比尔特的学者们专注于发展合作和提交赠款申请。 3.确保并记录UVP在经验丰富的UNZA领导下的长期影响 这一目标的重点是计划的影响，我们将通过跟踪职业生涯，赠款，出版物，重新评估， 搜索团队和发现。UNZA-范德比尔特伙伴关系已被证明在促进重新 UNZA的搜索能力。增加新的博士后奖学金和基础设施的形成， 增加UNZA赠款支持将迎来一个研究增长和影响的新时代。